Clinical trials: Erectile Dysfunctions
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Pudendal Nerve Injury, Erectile Dysfunction
Efficacy of Low-dose Percutaneous Electrical Stimulation in Patients With Erectile Dysfunction.
Erectile dysfunction is known as any alteration that produces a modification in the erectile response, whether it is due to organic, psychogenic or relational causes.
- Conditions
- Pudendal Nerve Injury, Erectile Dysfunction, Electric Stimulation
- Trial name
- Low-NEEP (NCT06397612)
- Testing
- Low Dose
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Camilo Jose Cela University
Erectile Dysfunction, Electric Stimulation
Treatment With Peripheral Nerve Stimulation of the Pudendal Nerve in Patients With Erectile Dysfunction
Erectile dysfunction is known as any alteration that produces a modification in the erectile response, whether of organic, psychogenic or relational cause.
- Conditions
- Erectile Dysfunction, Electric Stimulation, Pudendal Nerve
- Trial name
- NEEP (NCT06397625)
- Testing
- Percutaneous electrical neurostimulation
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Camilo Jose Cela University
Erectile Dysfunction, Peyronie's Disease
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis
This trial will study the safety and efficacy of intravenous and intracavernosal or interstitial delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Peyronie's disease…
- Conditions
- Erectile Dysfunction, Peyronie's Disease, Interstitial Cystitis
- Trial name
- NCT05147779
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Erectile Dysfunction, Coronary Artery Disease
Erectile and Ejaculatory Function Following Coronary Revascularization
This observational, cross-sectional study aims to compare erectile and ejaculatory function between men with a history of coronary revascularization and men without known coronary artery disease.
- Conditions
- Erectile Dysfunction, Coronary Artery Disease, Ejaculation Disorders
- Trial name
- NCT07878260
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Peyronie Disease, Erectile Dysfunction
Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.
- Trial name
- NCT06065436
- Testing
- Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Erectile Dysfunction Due to Venous Disorder, Erectile Dysfunction (ED)
Embolosclerotherapy Versus Deep Dorsal Vein Revascularization in Venogenic Erectile Dysfunction
Venous leakage is one of the causes of erectile dysfunction and can be managed using different treatment modalities, including surgical ligation and percutaneous embolization.
- Trial name
- venogenic ED (NCT07604194)
- Testing
- Endovascular embolosclerotherapy, Revacularization of deep dorsal vein
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Hospital
Erectile Dysfunction
IT Matters: The Erectile Restoration Registry
The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses
- Trial name
- NCT04200937
- Testing
- Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
- Where
- 25 sites in United States, China and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction, Urinary Incontinence
Male Pelvic Floor Muscle Rehabilitation Exercises
Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.
- Conditions
- Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
- Trial name
- NCT07451808
- Testing
- Male Pelvic Floor Rehabilitation #1
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction
The Impact of a Plant-based Meat Meal Versus an Animal Meat Meal on Erectile Function in Healthy Men.
The goal of this study is to determine whether erectile function is differentially impacted by a single plant-based meat meal versus a single animal meat meal in healthy men with normal erectile function.
- Trial name
- ERECTION 2 (NCT06273592)
- Testing
- Animal-based meal, Plant-based meat meal
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Erectile Dysfunction, Erectile Dysfunction (ED)
Satisfaction of Patients With Erectile Dysfunction With the Use of Sildenafil Oral Suspension Compared to Orodispersible Tablets
The goal of this observational retrospective study is to to evaluate treatment satisfaction with sildenafil oral suspension in patients with mild-to-moderate ED who were previously taking orodispersible sildenafil.
- Trial name
- SILOROS (NCT07676617)
- Testing
- Sildenafil Oral Suspension Compared to Orodispersible Tablets
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Prostate Cancer (Post Prostatectomy), Urinary Incontinence
Effects of Hypopressive Exercises on Urinary Incontinence and Erectile Dysfunction After Radical Prostatectomy
This randomized controlled trial investigates the effects of hypopressive exercises on urinary incontinence and erectile dysfunction in men following radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence, Erectile Dysfunction Following Radical Prostatectomy, Pelvic Floor Muscle Training
- Trial name
- NCT07101731
- Testing
- Pelvic Floor Muscle Training (PFMT), Hypopressive Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bartın Unıversity
Erectile Dysfunctions
The Purpose of This Study is to Evaluate the Efficacy and Safety of W2505.
The purpose of this study is to evaluate the efficacy and safety of W2505.
- Trial name
- NCT07859202
- Testing
- W2505, W2505-P1, W2505-R
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- GL Pharm Tech Corporation
Multiple Sclerosis, Erectile Dysfunction
Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis
The purpose of the study is to determine the effects of testosterone treatment on erectile function, fatigue, depression, cognitive function, quality of life, urinary incontinence, pain, and damage to neurons in male Multiple…
- Conditions
- Multiple Sclerosis, Erectile Dysfunction, Testosterone Deficiency
- Trial name
- NCT04601233
- Testing
- XYOSTED 75 milligram (mg) in 0.5 ML Auto-Injector
- Where
- United States
- Sponsor
- Tulane University
Coronary Artery Disease, Erectile Dysfunction
Pudendal Atherosclerosis by IVUS-NIRS in Men With Coronary Artery Disease
This prospective, single-center, exploratory study will evaluate the association between atherosclerotic and lipid plaque burden in the internal pudendal arteries, assessed by intravascular ultrasound and near-infrared…
- Conditions
- Coronary Artery Disease, Erectile Dysfunction, Atherosclerosis
- Trial name
- PUDENDAL-NIRS (NCT07856199)
- Testing
- Selective Pudendal Angiography, Pudendal IVUS-NIRS Imaging
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Central Militar
Erectile Dysfunction
Shockwave Therapy on Treating Erectile Dysfunction Following Nerve-sparing Radical Prostatectomy.
This study will investigate whether low-intensity extracorporeal shockwave therapy (LiESWT) can help men recover erectile function after nerve-sparing prostate cancer surgery.
- Trial name
- REVIVE (NCT07819084)
- Testing
- Low-Intensity Extracorporeal Shockwave Therapy, Standard of Care
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Erectile Dysfunction
Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
Adult subjects with mild to moderate and moderate ED who meet the study eligibility criteria will be enrolled in the study. The enrolled subjects will be randomized by a 1:1 ratio to receive the Active or Sham VERTICA® treatment.
- Trial name
- NCT06167733
- Testing
- VERTICA Active device
- Where
- 6 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- OHH-MED Medical Ltd
Hypogonadism, Male, Secondary Hypogonadism
AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism
AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…
- Trial name
- AIM-TEST (NCT07761546)
- Testing
- Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Varol TUNALI
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Tractography-Guided Nerve-Sparing in Prostate Cancer
Radical prostatectomy (RP) is an effective treatment leading to a high rate of oncological control. However, despite advances in robot-assisted RP, the genito-urinary function, especially erectile function and urinary continence…
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence Following Surgical Procedure
- Trial name
- PRO-TRACT (NCT07847385)
- Testing
- Prostate Tractography for Nerve-Sparing
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Massimo Valerio