Clinical trials: Erectile Dysfunction
Impotence, Erectile Dysfunction
The Management of Erectile Dysfunction With Placebo Only
Placebo-controlled randomized clinical trials (RCT) are the gold standard to provide applicable evidence for clinical practice. A vast number of RCTs for treatment of several disorders has shown a mean placebo effect of 30%.
- Trial name
- DAFA06 (NCT00882934)
- Testing
- Induction to efficient treatment, Doubt to the efficacy of treatment, Induction to ineffective treatment
- Volunteers
- 123 people
- Sponsor
- Rio de Janeiro State University
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Sildenafil in Treating Erectile Dysfunction in Patients With Prostate Cancer
RATIONALE: Sildenafil may be effective in helping patients who have undergone treatment for prostate cancer to have an erection for sexual activity and may improve sexual satisfaction and quality of life.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Radiation Toxicity, Sexual Dysfunction
- Trial name
- NCT00057759
- Testing
- sildenafil citrate
- Where
- 30 sites in United States
- Volunteers
- 115 people
- Sponsor
- Radiation Therapy Oncology Group
Male Erectile Disorder, Prostate Cancer
L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors
RATIONALE: L-arginine supplements may improve the quality of life and erectile function in men who are prostate cancer survivors.
- Conditions
- Male Erectile Disorder, Prostate Cancer, Radiation Toxicity
- Trial name
- NCT01105130
- Testing
- Oral L-Arginine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Wake Forest University Health Sciences
Biochemical Relapse Free Survival, Complications Rates (Erectile Dysfunction, GI, GU Complications)
HDR Brachytherapy vs SABR in Early-intermediate Prostate Cancer
This is single center prospective phase 2 randomized trial aiming to compare biochemical and clinical relapse free survival and toxicity profiles of stereotactic body radiotherapy (SBRT) versus high dose rate brachytherapy (HDRB)…
- Trial name
- NCT04870567
- Testing
- Stereotactic ablative radiotherapy, High dose rate brachytherapy
- Where
- Russia
- Volunteers
- 350 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Erectile Dysfunction
Low Intensity Shockwaves Therapy for the Treatment of Erectile Dysfunction. 12- Month Follow-Up
The purpose of this study is to evaluate the safety and effectiveness of the shockwave therapy to treat Erectile Dysfunction.
- Trial name
- NCT03670628
- Testing
- Shockwave therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Miami
Prostate Cancer, Erectile Dysfunction
A Study to Assess the Efficacy of Tadalafil to Treat Erectile Dysfunction After Radiotherapy of Prostate Cancer
This study has been designed to evaluate the efficacy and safety of a 20-mg dose of tadalafil administered "on demand" to patients with erectile dysfunction (ED) after external-beam radiotherapy (EBRT) of prostate cancer.
- Trial name
- NCT00122499
- Testing
- tadalafil
- Where
- Netherlands
- Sponsor
- Erasmus Medical Center
Erectile Dysfunction
Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot Study
The study involved the administration of pharmacotherapy and cognitive behavior psychotherapy to individuals suffering from erectile dysfunction. The study was randomized controlled trial with two arms involving a control group.
- Trial name
- NCT04179747
- Testing
- Cognitive Behavioral Psychotherapy, Sildenafil Citrate 50Mg Tab
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- International Islamic University, Islamabad
Erectile Dysfunction, Sexual Dysfunction, Physiological
Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
A study to assess the efficacy of vardenafil, taken as a tablet both nightly or 'as needed' (immediately before intended sexual activity) compared to placebo, to evaluate its tolerability and if it can help in recovery of…
- Trial name
- NCT00492635
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 86 sites in United States, Austria and 13 more
- Volunteers
- 628 people
- Sponsor
- Bayer
Erectile Dysfunction
Daily Avanafil for Erectile Dysfunction
In this study, the investigators tried to study the effect of daily avanafil on the serum level of endothelial function markers, as well as its impact on the erectile function in males with erectile and endothelial dysfunction by…
- Trial name
- NCT04374994
- Testing
- Avanafil 50 MG
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- University of Alexandria
Prostate Cancer, Erectile Dysfunction
The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy
Despite technological advances, incontinence and impotence remain significant side effects of radical prostatectomy (RP). Strategies have been developed to reduce the injury to the erection nerves (i.e.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Urinary Incontinence
- Trial name
- NCT04577222
- Testing
- Technical modification during radical prostatectomy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Rectal Cancer, Erectile Dysfunction
Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery
Erectile dysfunction (ED) is one of the commonest complications in men after rectal cancer treatment. The purpose of this study is to assess the safety and efficacy of autologous bone marrow mononuclear cells (BMMCs) or…
- Trial name
- NCT02648386
- Testing
- Laparoscopic surgery, NeuroRegen scaffold transplantation, NeuroRegen scaffold/BMMCs transplantation
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Chinese Academy of Sciences
Erectile Dysfunction
A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.
The purpose of this study is primarily to evaluate whether taking avanafil with alcohol causes the blood pressure to fall.
- Trial name
- NCT01054859
- Testing
- avanafil, alcohol
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction Due to Arterial Insufficiency
Platelet-rich Plasma (PRP) Injection for Treatment of Erectile Function
The primary objective of the present study is to investigate and compare the treatment efficacy of PRP injection vs placebo treatment in men with mild-moderate vasculogenic ED, as measured by IIEF.The secondary objective of the…
- Trial name
- NCT04050020
- Testing
- Platelet-Rich Plasma (PRP), Normal saline injection
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Erectile Dysfunction
Low-intensity Shockwaves Therapy for the Treatment of Patients With Moderate Vasculogenic Erectile Dysfunction
This is a double-blind, sham-controlled randomized, 2 parallel arms, clinical trial with a 12-month recruitment period. All patients will be PDE5I users/responders.
- Trial name
- NCT03518983
- Testing
- Dornier Aries2 device
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Erectile Dysfunction Due to Diseases Classified Elsewhere, Multiple Sclerosis, Relapsing-Remitting
Effect of Bio-electromagnetic Energy Regulation Therapy on Erectile Dysfunction in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is an inflammatory disease that affects the brain and spinal cord. There are potential impacts on neurological functions, including sensory and autonomic functions.
- Trial name
- NCT05615454
- Testing
- bio-electromagnetic energy regulation therapy (BEMER) machine model type: B.BOX CLASSIC, model NO: 420100, 12-15 Volt, (BEMER Int.AG, Liechtenstein product).
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction
BAY38-9456, 5/10/20mg, vs.Placebo in Erectile Dysfunction
Purpose of the study is:- To assess the efficacy and tolerability of vardenafil in male subjects suffering from erectile dysfunction as compared to placebo- To assess the influence of vardenafil on the self-esteem and…
- Trial name
- NCT00665054
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bayer
Vasculogenic Erectile Dysfunction
Endothelial Markers and Tadalafil Response
This prospective cohort study will recruit eligible men attending the Urology/Andrology outpatient clinic. Baseline assessment will include demographic and clinical data, cardiovascular risk assessment, erectile-function…
- Trial name
- NCT07773103
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Prostate Cancer
Androcur Non-interventional Study Among Patients With Carcinoma of the Prostate
Cyproterone acetate (CPA) is a steroidal antiandrogen which has affinity with progesterone and with glucocorticoid receptors. Cyproterone acetate is long-term proven effective treatment of inoperable carcinoma of the prostate.
- Trial name
- ANES (NCT00919022)
- Testing
- Cyproterone Acetate (Androcur, BAY94-8367)
- Where
- Czechia
- Volunteers
- 194 people
- Sponsor
- Bayer
Urinary Incontinence, Erectile Dysfunction
Effectiveness of Physiotherapy to Treat the Urinary Incontinence and Erectile Dysfunction Post Retropubic Prostatectomy
The prostate cancer is the most common parenchymal neoplasia in men over 45 years old. Radical prostatectomy is curative treatment is most used today.
- Trial name
- NCT02226237
- Testing
- group of pelvic floor exercises, anal electrostimulation group
- Where
- Brazil
- Volunteers
- 237 people
- Sponsor
- Barretos Cancer Hospital