Clinical trials: Erectile Dysfunction
Diabete Mellitus, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Impact of Pilates Exercises on Diabetic Erectile Dysfunction.
Erectile dysfunction (ED) has a prevalence of 52.5% in diabetic male patients, as described in a meta-analysis of 145 studies, including 88,577 men with type 1 and type 2 diabetes.
- Conditions
- Diabete Mellitus, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Pilates Exercise, Pelvic Floor Muscle Exercise
- Trial name
- PilatesDED2025 (NCT07293156)
- Testing
- Pilate Exercises, Home based pelvic floor muscle training, Sildenafil therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Erectile Dysfunction
Registry for Patients Undergoing Penile Prosthesis Implantation for Male Erectile Dysfunction
Prospective collection of pre-defined parameters on the surgical treatment of male erectile dysfunction using Penile Prosthesis Implants (PPIs).
- Trial name
- PHOENIX (NCT03849586)
- Where
- 30 sites in Belgium, France and 6 more
- Volunteers
- 1,076 people
- Sponsor
- European Association of Urology Research Foundation
Erectile Dysfunction
L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction
Erectile dysfunction is a common male sexual health problem that may affect quality of life and sexual relationships. Tadalafil 5 mg once daily is an established oral treatment for erectile dysfunction.
- Trial name
- NCT07642505
- Testing
- L-Citrulline, Tadalafil
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Beni-Suef University
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Erectile Dysfunction
Penile Rehabilitation in Patients With Erectile Dysfunction After Pelvic Fracture Urethral Injury Using Low-intensity Shock Wave.
the efficacy and safety of low intensity shock wave therapy (LiSWT) as an ED treatment. Olsen et al. demonstrated that LiSWT might be a possible solution in some ED patients of organic origin .
- Trial name
- NCT07460167
- Testing
- ELvation® Piezowave² linear focused piezoelectric shock wave device (Richard Wolf, Vernon Hills, IL, USA) effect of itsshockwaves on Erectile dysfunction
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- South Valley University
Prostate Cancer Adenocarcinoma
Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C)
Reduction of dose to or 'sparing' of neurovascular structures during stereotactic ablative body radiotherapy (SAbR) for localized prostate cancer will improve retention of sexual potency, while retaining excellent oncologic…
- Trial name
- POTEN-C (NCT03525262)
- Testing
- 30Gy (Gray) planning target volume (PTV)
- Where
- 8 sites in United States
- Volunteers
- 124 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Erectile Dysfunction
Impact of Depression Severity on Sexual Dysfunction
Assess the relationship and the prevalence…" "To determine the prevalence of erectile dysfunction and premature ejaculation among depressed male patients and evaluate their association with depression severity."
- Conditions
- Depression, Erectile Dysfunction, Premature Ejaculation
- Trial name
- IODOEDPE (NCT07627477)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Erectile Dysfunction
Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction
The purpose of this research study is to evaluate whether the combination of Shock Wave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and…
- Trial name
- COCKTAIL (NCT05048667)
- Testing
- Shock Wave therapy (SWT), Platelet Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Miami
Erectile Dysfunction (ED), Erectile Dysfunctions
A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction
This is a single arm dose escalation trial of a mucoadhesive intraurethral polymer suspension of alprostadil (ST-04) and will investigate the efficacy of 3 dose levels of ST-04 in adult males with a clinical diagnosis of Erectile…
- Conditions
- Erectile Dysfunction (ED), Erectile Dysfunctions, Erectile Function
- Trial name
- NCT07601646
- Testing
- ST-04
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Ryan Flannigan, MD
Erectile Dysfunction
Platelet-Rich Plasma With or Without Tadalafil for Erectile Dysfunction
Platelet-rich plasma is being studied as a regenerative treatment option for erectile dysfunction, but it is unclear whether adding daily tadalafil gives additional benefit over platelet-rich plasma alone.
- Trial name
- NCT07602608
- Testing
- Tadalafil, Intracavernosal Platelet-Rich Plasma Injection
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Radical Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy
EVERiST: Impact of Image Detected Accessory Pudendal Artery on Erection Recovery After Nerve Sparing Prostatectomy
Prostate cancer is the most common cancer amongst men in the United Kingdom, and two common curative treatments are surgery to remove the prostate (radical prostatectomy) or radiotherapy.
- Conditions
- Radical Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Due to Arterial Insufficiency, Robotic Radical Prostatectomy
- Trial name
- EVERiST (NCT07597798)
- Testing
- Robotic Radical Prostatectomy, Penile doppler ultrasound
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College, London
Erectile Dysfunction
A Single Arm Study of Extracorporeal Shockwave Therapy for Management of Erectile Dysfunction
This is a device study (while the device has been patented and cleared by the FDA, the indication of the use for Erectile Dysfunction has been yet approve).
- Trial name
- EXSTACY (NCT07592533)
- Testing
- Shockwave therapy
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of California, San Francisco
Erectile Dysfunction
Autologous PRP and Focal Shock Waves for Erectile Dysfunction
The goal of this clinical trial is to learn if Platelet-rich plasma (PRP) combined with Shock-wave therapy (SWT) works to treat moderate or mild to moderate erectile dysfunction.
- Trial name
- NCT06433596
- Testing
- Platelet-rich plasma, Shock waves therapy
- Where
- Spain
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Elexial Research Limited
Erectile Dysfunction, Left Ventricular Diastolic Dysfunction
Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome
Metabolic syndrome is associated with an increased risk of cardiovascular disease and is commonly accompanied by erectile dysfunction and subclinical cardiac dysfunction.
- Conditions
- Erectile Dysfunction, Left Ventricular Diastolic Dysfunction, Metabolic Syndrome
- Trial name
- METDDED (NCT07563647)
- Testing
- Tadalafil 5 mg, SGLT-2 inhibitor, Tadalafil plus SGLT2 inhibitors
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Penile Injection Therapy, Erectile Dysfunction
Penile Injection Anxiety
The purpose of this study is to help us understand more about your experience with penile injection therapy. Many men become anxious when thinking about penile injections. We would like to understand more about this anxiety.
- Conditions
- Penile Injection Therapy, Erectile Dysfunction, Radical Pelvic Surgery
- Trial name
- NCT00582231
- Testing
- Questionnaires.
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Erectile Dysfunction
A Prospective Comparative Study of Autologous Bone Marrow-Derived and Adipose Tissue-Derived Mesenchymal Stem Cells Versus Platelet-Rich Plasma and Standard Therapy in Patients With Organic Erectile Dysfunction
Erectile dysfunction (ED) is a common condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual activity.
- Trial name
- NCT07544537
- Testing
- Autologous Bone marrow-derived Mesenchymal Stem Cells (BMSC), Autologous Platelet-Rich Plasma (4 mL), Autologous Platelet-Rich Plasma (6 mL)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- National Scientific Medical Center, Kazakhstan
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy
This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- MPE-RP (NCT07520916)
- Testing
- Mobile-Based Perioperative Education Program, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Giresun University
Prostate Cancer, Erectile Dysfunction
Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery
The purpose of this study is to test two different ways to help men with sexual rehabilitation.
- Trial name
- NCT02706561
- Testing
- questionnaires, three in-person sessions, monthly phone calls
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Erectile Dysfunction
Radial Shockwave Therapy for Erectile Dysfunction
Objective: To evaluate the efficacy and safety of radial shock waves for the treatment of erectile dysfunction [ED]. Patients and methods: Randomized, double-blind clinical trial.
- Trial name
- NCT03596047
- Testing
- Radial wave therapy
- Where
- Colombia
- Volunteers
- 80 people
- Sponsor
- Boston Medical Group
Erectile Dysfunction With Diabetes Mellitus
Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction
The goal of this prospective randomized controlled clinical study is to evaluate the effectiveness and safety of intracavernosal injections of umbilical cord-derived mesenchymal stem cells (MSCs) and umbilical cord-derived…
- Trial name
- NCT07480161
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cells, Umblical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent