Clinical trials: Environmental Impact
Bariatric Surgery Candidate
Impact of Bariatric Surgery on the Gut Environment
The purpose of this study is to investigate the impact of bariatric surgery on the gut health. Patients operated with Roux-en-Y gastric bypass or sleeve gastrectomy and obese patients who want too loose weight with a traditional…
- Trial name
- IMPORTUNE (NCT04345328)
- Where
- Belgium
- Volunteers
- 151 people
- Sponsor
- KU Leuven
Clinician Perception, Clinician Attention
How Does Task Loading in PICU Impact on Clinician Situational Awareness and Awareness of the Passage of Time?
There is little published literature on the subject of clinician perception of trends in patient observations on PICUs (Paediatric Intensive Care Units) and how this situational awareness is impacted on by clinical tasks.
- Trial name
- NCT05383222
- Testing
- Technical task, Administrative task
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Mediastinal and Hilar Lymphadenopathy
Study of Procedural Efficiency in EBUS With Dual Versus Single NEEDLEs: Evaluating the Value of a Second Needle in EBUS as it Pertains to Economic and Environmental Impact
Currently, the EBUS bronchoscopy procedure uses either one or two needles to perform the biopsy of the lymph node based on physician preference.
- Trial name
- SPEED NEEDLE (NCT07218042)
- Testing
- We randomized patients to the two arms above; there was no specific intervention performed other than randomizing patients to one or two needles.
- Where
- 3 sites in United States
- Volunteers
- 126 people
- Sponsor
- Christopher Kapp
Asthma
Asthma in the Delta Region of Arkansas: Characterization of Disease and Impact of Environmental Factors
The purpose of the study is to evaluate asthma and examine the homes of children with asthma living in rural areas of the state.
- Trial name
- ADRA (NCT00590304)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Breast Cancer, Mastectomy
Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer
The goal of this clinical trial is to learn if the AMADeuS care pathway is as safe as usual hospital care and works as well for pain control in women having mastectomy with immediate prepectoral breast reconstruction.
- Conditions
- Breast Cancer, Mastectomy, Prepectoral Breast Reconstruction, ERAS Programmes
- Trial name
- AMADeuS (NCT07510698)
- Testing
- AMADeuS Perioperative Pathway, Usual Perioperative Care
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Oral Feeding Outcomes, Neurodevelopment Outcome
Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)
Infants born with congenital defects may require major surgery in the neonatal period. These infants are at risk for neurodevelopmental impairments.
- Trial name
- H-HOPE (NCT07372898)
- Testing
- H-HOPE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Diarrhea, Malaria
Impact Evaluation of Community-Based Health Programs in Rwanda
Community Health Clubs to improve local sanitation, hygiene and health conditions have been implemented in several countries in Africa and Asia with some success.
- Trial name
- CBEHPP (NCT01836731)
- Testing
- Classic Intervention, Minimum Intervention
- Where
- 2 sites in Rwanda
- Volunteers
- 8,718 people
- Sponsor
- Georgetown University
Bowel Disease, Liver Diseases
The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
Major abdominal surgery - like non-laparoscopic bowel resection, liver, gastric, or pancreas surgery - is performed under general anesthesia.
- Conditions
- Bowel Disease, Liver Diseases, Pancreas Disease, Anesthesia; Functional
- Trial name
- NCT04021264
- Testing
- Ropivacaine-Sufentanil, Dextrose 5
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Homeless Persons, Wound and Injuries
The WARM Study is a Pilot Study That Aims to Investigate the Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg.
Providing healthcare to homeless people is a key and challenging task, both for society as a whole and for medical and psychosocial professionals.
- Conditions
- Homeless Persons, Wound and Injuries, Chronic Wound Care, Homelessness
- Trial name
- WARM (NCT07640672)
- Testing
- Wound care at the University Hospital and in the Johanniter mobile wound care unit
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Augsburg
Hepatocellular Carcinoma
Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the 6th most common cancer in the world but the 2nd most important cause of cancer death. Because of its highly heterogeneous nature, the current approach to identifying druggable targets have…
- Trial name
- PLANET (NCT03267641)
- Where
- 6 sites in Malaysia, Philippines and 2 more
- Volunteers
- 86 people
- Sponsor
- National Cancer Centre, Singapore
Diet Pattern Analysis, Environmental Impact
Dairy Product Consumption and Impact on Nutritional Adequacy, Environment and Diet Cost
This is a secondary analysis of dietary, demographic and health parameter data collected in the 2008/09-2011/12 National Diet and Nutrition Survey (NDNS), UK to determine the roles of dairy products in sustainable diets by…
- Conditions
- Diet Pattern Analysis, Environmental Impact, Nutrient Intakes, Cardio-metabolic Health
- Trial name
- NCT03407248
- Where
- United Kingdom
- Volunteers
- 1,655 people, healthy volunteers welcome
- Sponsor
- University of Reading
Obesity, Food Labeling
Nudging Nutrition With Monetary Incentives Environmental Cues
The investigators hypothesize that monetary incentives and messaging, such as making nutritious foods relatively less expensive than less nutritious foods and framing the price difference in a positive or negative way, will…
- Conditions
- Obesity, Food Labeling, Health Behavior, Diet
- Trial name
- NCT02461108
- Testing
- Subsidy, Tax, Tax and subsidy
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Cornell University
Myocardial Infarction
Impact of Environmental Exposure at Home Address on One-year Post-myocardial Infarction Survival
Numerous studies have explored the effects of environmental exposure to noise, air pollution and proximity to "natural" areas on various conditions.
- Trial name
- ENVI-MI (NCT05449912)
- Testing
- Collection of environmental exposure data
- Where
- France
- Volunteers
- 982 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Decision-making
Impact of Perceptive, Executive and Emotional Factors on Decision-making of Pedestrian Face to Autonomous Vehicles.
The VASIS project aims to assess the impact of perceptual, executive and emotional factors on decision-making in the context of pedestrian crossing in an industrial environment involving autonomous vehicle traffic (forklift).
- Trial name
- VASIS (NCT06255275)
- Testing
- neurocognitifs tests + pedestrian crossign whith virtual reality
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Enteropathy
The Impact of Legumes vs Corn-soy Flour on Environmental Enteric Dysfunction in Rural Malawian Children 6-11 Months
To determine if 6 months of legume-based complementary foods is effective in reducing or reversing EED and linear growth faltering in a cohort of Malawian children, aged 6-11 months to see if these improvements are correlated…
- Trial name
- NCT02472262
- Testing
- Cow pea complementary food, Corn soy flour, Common bean
- Where
- Malawi
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Atopic Dermatitis
Atopic Dermatitis: Sub-Saharan Africa vs. Central Europe
Many people are affected by atopic dermatitis (AD) worldwide. However, clinical studies on AD in Sub-Saharan Africa are rare and there is a lack of knowledge about possible differences in pathogenesis between European and African…
- Trial name
- NCT05363904
- Testing
- Observation
- Where
- 3 sites in Madagascar, Switzerland and 1 more
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Heat Stress, Diet Induced Thermogenesis
Carbohydrate or Protein Drinks Before Exercise in the Heat
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1.
- Conditions
- Heat Stress, Diet Induced Thermogenesis, Protein Consumption
- Trial name
- NCT07646990
- Testing
- Protein shake, Carbohydrate shake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Providence College
Choice Behavior, Dietary Habits
Plant-Based Defaults
In this study, participants at six different academic events were randomly assigned to one of two conditions: (1) a default meat group, where the default choice was a meal with meat and participants had the option of opting out…
- Trial name
- NCT06554743
- Testing
- Default Veg, Default Meat
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cognitive Impairment, Mild, Sleep
Are Cognition and Sleep Affected by Exposure to Carbon Dioxide and Bio Effluents During Sleep?
The aim of the project is to examine whether children's sleep and cognition are affected by exposure to CO2 and other bio effluents during sleep.
- Conditions
- Cognitive Impairment, Mild, Sleep, Environmental Exposure
- Trial name
- NCT03558698
- Testing
- Good ventilation, Ventilation CO2, Poor Ventilation
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada