Clinical trials: Energy Expenditure, active
Cardiovascular Diseases, Natriuretic Peptides
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes…
- Conditions
- Cardiovascular Diseases, Natriuretic Peptides, Cardiometabolic Diseases, Energy Expenditure
- Trial name
- NCT05216042
- Testing
- Study diet, Exercise capacity VO2 max determination, Exercise Challenge
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Energy Expenditure, Physical Activity
Seasonal Variation in Energy Expenditure, Water Turnover, and Physical Activity in Adults
This prospective observational study will investigate seasonal variation in total energy expenditure, water turnover, and physical activity in healthy adults living in or near Aberdeen, Scotland.
- Trial name
- NCT07856316
- Testing
- Seasonal Environmental Exposure
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Resting Energy Expenditure, Indirect Calorimetry
Comparison of the Effects of SIMV-PC and SIMV-VC Ventilation Modes on Resting Energy Expenditure
The primary objective of this prospective observational study is to compare the effects of synchronized intermittent mandatory ventilation in pressure-controlled mode (SIMV-PC) and volume-controlled mode (SIMV-VC) on resting…
- Trial name
- NCT07790341
- Testing
- Volume-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- 41 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Targeted Temperature Management, Cardiac Arrest
Resting Energy Expenditure and Substrate Consumption in Cardiac Arrest Patients Under Target Temperature Management
This study is a single-center, prospective, observational study. According to the sample size formula, an estimated 40 cases should be collected, all of whom are from the emergency intensive care unit.
- Conditions
- Targeted Temperature Management, Cardiac Arrest, Resting Energy Expenditure, Nutrition
- Trial name
- NCT06575101
- Testing
- Target Temperature Management Treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tang Ziren
Energy Expenditure, Body Composition
Energy Expenditure and Body Composition of Infants and Young Children (6-24 Months Old) in Asia
This project is a collaboration between International Atomic Energy Agency (IAEA), FAO Regional Office for Asia and The Pacific, and Mahidol University, Thailand to carry out the study on doubly-labeled water for assessment of…
- Conditions
- Energy Expenditure, Body Composition, Infants and Young Children, Infant and Young Child Feeding
- Trial name
- NCT06287697
- Testing
- No intervention
- Where
- Thailand
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Stroke, Osteopathic Medicine
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
Stroke remains the leading cause of severe disability, and survivors frequently have incomplete recovery. More than half of older survivors have impaired mobility which contributes to poorer quality-of-life (QoL) and suffering.
- Conditions
- Stroke, Osteopathic Medicine, Physical Examination, Heart Rate Variability (HRV)
- Trial name
- SOMADC-CC (NCT07737873)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Diabetes Mellitus, Cardiovascular Diseases
NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reasons for this are incompletely understood.
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases, Insulin Sensitivity/Resistance, Metabolic Disease
- Trial name
- NCT04055428
- Testing
- Sacubitril, Valsartan 97-103 mg Oral Tablet, Valsartan 160 mg, Intravenous Glucose Tolerance Test
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Energy Balance, Energy Expenditure
Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females
There is growing evidence that males and females may exhibit different acute responses and long-term adaptations to exercise training.
- Conditions
- Energy Balance, Energy Expenditure, Males and Females, Resistance Exercise
- Trial name
- NCT07444021
- Testing
- resistance exercise (males), resistance exercise (females)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Glucose Intolerance, Energy Expenditure
Effects of Acute Sleep Deprivation on Health
This study will investigate whether various types of regular exercise can provide protective effects against metabolic abnormalities induced by sleep restriction.
- Conditions
- Glucose Intolerance, Energy Expenditure, Vascular Stiffness, Cognition
- Trial name
- NCT07403864
- Testing
- Normal sleep, Partial sleep deprivation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Metabolic Regulation, Energy Expenditure
Effects of Intermittent Running on Metabolic Health
The purpose of this study is to investigate the suitability of intermittent exercise of long and short intervals at lower intensities than HIIE on energy expenditure during and post-exercise compared to MICE, as well as determine…
- Trial name
- NCT06962605
- Testing
- Moderate-intensity continuous running (MICE: 60% V̇O2max), 5-minute interval running (5MIN), 2-minute interval running (2MIN)
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Cardiovascular Diseases, Insulin Sensitivity/Resistance
VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway
This study investigates the potential of vericiguat, a soluble guanylate cyclase stimulator, to improve cardiometabolic health in obese Black individuals with insulin resistance by directly enhancing cyclic guanosine…
- Conditions
- Cardiovascular Diseases, Insulin Sensitivity/Resistance, Metabolic Disease, Metabolism
- Trial name
- VITAL-IMPACT (NCT06320951)
- Testing
- Vericiguat 10 MG, Insulin Sensitivity Test, Resting Energy and Exercise Energy Expenditure Assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Human Energy Expenditure
Measurements of Water in Breath and Saliva
This study proposes to demonstrate the feasibility of measuring 2H:1H and 18O:16O in saliva and breath by comparing the natural abundances of 2H:1H and 18O:16O in saliva and urine of un-dosed humans.
- Trial name
- NCT03233256
- Testing
- Feasibility of measuring 2H:1H and 18O:16O in saliva and breath.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infant Body Composition and Metabolism, Metabolism
Studying Phenotypic Risks for Obesity and Underlying Traits in Young Infants
The purpose of this research study is to understand how infants metabolize different meals and to develop clinical tools which identify infants as having two different phenotypes.
- Conditions
- Infant Body Composition and Metabolism, Metabolism, Energy Expenditure, Infant Formula
- Trial name
- SPROUT (NCT07096011)
- Testing
- Meal Test - Human Milk, Meal Test - Infant Formula
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Energy Expenditure, Exercise
Sources and Mechanisms of Energy Compensation
Excess energy, obesity and obesity-related diseases are important global health issues. Although it is known that obesity is an issue of energy balance, the components of energy expenditure seem to be inter-related in complex…
- Conditions
- Energy Expenditure, Exercise, Energy Intake, Food Preferences
- Trial name
- NCT06432517
- Testing
- Power Bike（Ergoselect 100P）
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Energy Expenditure, Obesity
Brown Fat Activation and Browning Efficiency Augmented by Chronic Cold and Nutraceuticals for Brown Adipose Tissue-mediated Effect Against Metabolic Syndrome (BEACON BEAMS Study)
Our body fat (adipose tissue) is largely made up of white adipose tissue (WAT) that stores surplus energy as white fat depots. In addition, adult humans have another type of fat similar to the brown fat in babies that burns up…
- Conditions
- Energy Expenditure, Obesity, Brown Adipose Tissue
- Trial name
- NCT04595006
- Testing
- Cold Stimulation (CS), Browning Nutraceutical (BN), Cold Stimulation and Browning Nutraceutical (CSBN)
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Energy Expenditure, Metabolic Syndrome
The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome
During this study, the effect of short-chain fatty acids on blood lipaedemia, glycemia, anthropometrics, blood pressure and energy expenditure will be investigated.
- Conditions
- Energy Expenditure, Metabolic Syndrome, Anthropometry, Body Composition
- Trial name
- 12OATS (NCT06951386)
- Testing
- with short-chain fatty acids enriched drink, unenriched oat drink
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- KU Leuven
Postmenopause, Energy Expenditure
Resting Energy Expenditure in Postmenopausal Women
Obesity and its associated comorbidities are rising at an alarming rate, particularly among postmenopausal women. Menopause, characterized by a decline in estradiol and progesterone levels, is often accompanied by weight gain.
- Conditions
- Postmenopause, Energy Expenditure, Hormone Replacement Therapy
- Trial name
- MenoBOLISM (NCT06905886)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern