Clinical trials: Endovascular Surgery
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vascular Disease
Transferability and Cost-effectiveness of PROSPECT in Surgical Trainees
To design, validate and prove cost-effectiveness of a comprehensive endovascular simulation curriculum consisting of cognitive and psychomotor skills training for endovascular management of symptomatic vascular disease in the…
- Trial name
- PROSPECT (NCT01965860)
- Testing
- additional curriculum (E-learning + simulation), additional E-learning
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Ghent
Atherosclerosis, Ischemia Limb
Efficacy and Safety Comparison of the Open Surgical and Endovascular Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Above the Knee, TASC II, Type D.
Endovascular revascularization and open bypass grafting above the knee show comparable results in primary 2-year patency (about 65%) in medium-length lesions - TASC II, C (Pereira et al, 2006).
- Conditions
- Atherosclerosis, Ischemia Limb, Superficial Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- NCT04588571
- Testing
- Endovascular recanalization with angioplasty and stenting with the biomimetic interwoven nitinol stent, Femoropopliteal proximal bypass
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Radiation Exposure
Suspended Personal Protection System Versus Conventional Protection (Aka Zero-Gravity vs Shield and Apron)
This trial investigates operator radiation doses when performing standardized procedures using two different means of radiation protection, namely conventional lead shield and apron versus suspended protection system…
- Trial name
- NCT04078165
- Testing
- Zero-Gravity, Conventional radiation protection
- Where
- Finland
- Volunteers
- 72 people
- Sponsor
- Helsinki University Central Hospital
Failure in Endovascular Therapy, Splanchnic Aneurysm
Salvage Surgeries for Splanchnic Artery Aneurysms After Failed Endovascular Therapies: Cases Series
A retrospective review was performed for consecutive patients (from 2019 to 2021) who underwent salvage surgeries following failed endovascular therapies for splanchnic artery aneurysms in a tertiary referral center.
- Conditions
- Failure in Endovascular Therapy, Splanchnic Aneurysm, Mass Effect, Surgery
- Trial name
- NCT05727956
- Testing
- Aneurysmectomy
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- China Medical University Hospital
Peripheral Arterial Disease
A Study Evaluating the Endovascular Treatment of Subjects With Stenotic or Restenotic Lesions of the Common Femoral Artery With the Supera Vascular Mimetic Implant Compared to Surgical Common Femoral Artery Endarterectomy
The SUPERSURG RCT trial investigates the efficacy and safety of the endovascular treatment of stenosis or restenosis in the common femoral artery (CFA) of patients presenting with Rutherford classification 2,3 or 4 with a Supera…
- Trial name
- SUPERSURG-RCT (NCT04349657)
- Testing
- Supera Peripheral Stent System treatment group, Endarterectomy treatment group
- Where
- 13 sites in Belgium, Netherlands and 1 more
- Volunteers
- 286 people
- Sponsor
- KANDO Research
Cytogenetic Abnormality, Radiation Exposure
Genomic Instability in Vascular Surgeons
The past two decades have witnessed the development and growth of the endovascular techniques, however, this new technology is not exempt from risks, since its use requires an ionizing radiation exposure to both patients and…
- Trial name
- IRADIENT (NCT04363190)
- Testing
- Cytogenetic analysis
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Endovascular Carotid Surgery, Preoperative Hypotension
Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery
The effects on brain perfusion of the two currently vasopressors used to treat accidental hypotension occurring during carotid surgery (i.e.
- Trial name
- VP-hTA-XCar (NCT01794273)
- Testing
- ephedrine and phenylephrine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Carotid Stenosis, Coronary Artery Disease
Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients
Prospective, single-center, clinical registry of patients with symptomatic/critical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and/or severe valvular heart…
- Conditions
- Carotid Stenosis, Coronary Artery Disease, Valvular Heart Disease, Myocardial Infarction
- Trial name
- SIM-GUARD (NCT04973579)
- Testing
- Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
The Use of Cardiovascular Biomarkers in Abdominal Aortic Surgery
The aim of the present study is the evaluation of cardiovascular biomarkers in patients with abdominal aortic aneurysms (AAA) or abdominal aortic occlusive disease AOD) undergoing open (OR) or endovascular aortic repair (EVAR)…
- Trial name
- BIAS (NCT02122497)
- Testing
- abdominal aortic surgery
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Prim PD Dr Afshin Assadian
Vascular Surgical Procedures, COVID-19
Outcomes of Vascular Surgery in COVID-19 Infection: National Cohort Study
There is an urgent need to understand the outcomes of COVID-19 infected patients who undergo surgery, specially vascular surgery.
- Conditions
- Vascular Surgical Procedures, COVID-19, Postoperative Complications
- Trial name
- Covid-VAS (NCT04333693)
- Testing
- Vascular surgery
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
AVM (Arteriovenous Malformation) Intracranial
Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment
Cerebrovascular malformations (CVMs) are a heterogeneous group of disorders and can be classified histopathologically into five main categories: arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVDs)…
- Trial name
- NCT05729295
- Testing
- Endovascular embolization or surgery
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Wound
The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System
The objective of this trial is to demonstrate the safety and effectiveness of the Rex Medical Closer Vascular Sealing System in sealing femoral arterial access sites.
- Trial name
- Closer (NCT02136004)
- Testing
- Closer VSS
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rex Medical
Aortic Aneurysm
Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)
A multi-center, randomized clinical trial that will compare endovascular repair with standard open surgery in the repair of abdominal aortic aneurysms (AAA).
- Trial name
- OVER (NCT00094575)
- Testing
- Endovascular Repair, Standard Open Repair
- Where
- 42 sites in United States
- Volunteers
- 881 people
- Sponsor
- VA Office of Research and Development
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Endovascular Procedure, Hemodialysis
Medico-economic Evaluation of the Creation of Arteriovenous Access for Hemodialysis Between Surgical Technique and Endovascular Technique in Patients with End-stage Renal Disease
This multicenter 1 :1 randomized controlled trial aims at comparing the cost-effectiveness of endovascular arteriovenous fistula (AVF) creation using Ellipsys® and WaveLinQ® devices with traditional surgical AVF creation for…
- Trial name
- ENDOFAV (NCT06679907)
- Testing
- WaveLinQ® device, Ellipsys® device, No device
- Where
- 11 sites in France
- Volunteers
- 252 people
- Sponsor
- University Hospital, Bordeaux
Aortic Arch, Aortic Diseases
CILCA Arch Registry: Management and Outcomes of Open and Endovascular Repair
This registry aims to provide insights on the pathogenic mechanisms that expose subjects with CILCA arch to the increased risk of postoperative complications.
- Conditions
- Aortic Arch, Aortic Diseases, Bovine Arch
- Trial name
- NCT04995640
- Testing
- open cardiovascular repair or endovascular treatment (TEVAR)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Donato
Near-Infrared Spectroscopy in Endovascular Neurosurgery
The Relationship Among rSO2, MAP, et al by Near-Infrared Spectroscopy in Endovascular Neurosurgery
record,describe and discuss the relationship among rSO2, MAP,CAM value, vital organ disfunction and the outcome of patients after operation by Near-Infrared Spectroscopy in Endovascular Neurosurgery
- Trial name
- NCT02356133
- Volunteers
- 43 people
- Sponsor
- China International Neuroscience Institution
Abdominal Aortic Aneurysm, Carotid Atherosclerosis
Preconditioning Shields Against Vascular Events in Surgery
Major vascular surgery involves operations to repair swollen blood vessels, clear debris from blocked arteries or bypass blocked blood vessels.
- Conditions
- Abdominal Aortic Aneurysm, Carotid Atherosclerosis, Critical Lower Limb Ischaemia
- Trial name
- SAVES (NCT01691911)
- Testing
- Remote preconditioning
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Central Retinal Vein Occlusion
Phase I RVC With Ocriplasmin for CRVO
In central retinal vein occlusion (CRVO) a blood clot blocks the venous outflow of the entire retinal circulation. This leads to retinal and vitreous hemorrhages, retinal edema and neovascularization.
- Trial name
- RVC_CRVO (NCT02747030)
- Testing
- Ocriplasmin intravenously
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven