Clinical trials: Endotracheal Aspiration
Secretion Removal Above ETT Cuff
Evaluation of Above the Cuff Suctioning During General Anesthesia
The aim of this prospective, randomized, pilot study is compare ease of tracheal intubation, amount of microaspiration and efficacy of secretion removal using three FDA (Food and Drug Administration)-cleared endotracheal tubes…
- Trial name
- NCT01386879
- Testing
- methylene blue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Ventilator Associated Pneumonia, Aspiration
Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT)
This is a single centre, open-label, feasibility randomised controlled trial. The study aims to assess the feasibility of conducting an RCT to compare the PneuX ETT with standard care in hospitalised patients requiring mechanical…
- Conditions
- Ventilator Associated Pneumonia, Aspiration, Infections, Ventilator Lung
- Trial name
- VAP-X (NCT05410106)
- Testing
- PneuX Endotracheal Tube, Standard care (Taperguard, Covidien)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cardiff and Vale University Health Board
Pneumonia
Prevention of Pneumonia Comparing Ceftriaxone With Subglottic Aspiration
The primary purpose of the trial is to compare the efficacy and safety of two measures which claim to prevent early-onset ventilator-associated pneumonia.
- Trial name
- NCT00374959
- Testing
- ceftriaxone, Endotracheal tube for aspiration of subglottic secretions.
- Where
- 3 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitario Principe de Asturias
Meconium Aspiration Syndrome
Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies
The purpose of this study is to evaluate the role of endotracheal suction on the occurrence of meconium aspiration syndrome in depressed meconium stained babies.
- Trial name
- ETMAS (NCT01758822)
- Testing
- No endotracheal suction
- Where
- India
- Volunteers
- 175 people
- Sponsor
- Lady Hardinge Medical College
Preterm, Pain
The Effect of Touch Methods on Pain and Physiological Parameters in Preterm Infants During Endotracheal Aspiration
Recurrent and painful interventions such as heel lancing, venipuncture, dressing change, endotracheal aspiration are frequently performed in neonatal intensive care units (NICU).
- Conditions
- Preterm, Pain, Infant ALL
- Trial name
- NCT05784857
- Testing
- Touch Methods
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Endotracheal Aspiration
Effect of Touch Methods in Preterm Infants During Endotracheal Aspiration
The purpose of this study was to determine the effect of gentle human touch (GHT) and Yakson methods during endotracheal suctioning on pain, comfort and physiologic parameters response in preterm infants.
- Trial name
- NCT06308991
- Testing
- Yakson touch, Gentle Human Touch, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Airway Extubation, Pneumonia, Bacterial
Relation Between the Volume of Subglottic Secretion and Risk of Extubation Failure in ICU Patients (SEGEX)
This study evaluates the relation between the volume of subglottic secretion before airway extubation and the risk of extubation failure in the ICU patient.
- Conditions
- Airway Extubation, Pneumonia, Bacterial, Aspiration of Subglottic Secretions
- Trial name
- SEGEX (NCT03946371)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pneumonia, Aspiration
Validation of Aspiration Markers in Intubated Patients
The goal of this interventional study is to test Quinine as marker of aspiration (endotracheal tube [ETT] cuff leakage) in mechanically ventilated, critically ill patients.
- Trial name
- NCT02598713
- Testing
- Aspiration Marker
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Tracheal Stenosis
Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway Procedures
The purpose of the study is to prospectively assess the use of a modified tracheal balloon dilator that allows gas flow (oxygenation and ventilation) through the device while inflated during dilatation.
- Trial name
- NCT02796326
- Testing
- improved tracheal balloon dilatation
- Where
- South Africa
- Volunteers
- 20 people
- Sponsor
- University of Cape Town
Aspiration of Subglottic Secretions
Aspiration of Subglottic Secretions Using Hi-Lo Evac Endotracheal Tube: Tube Size and Incidence of Suction Lumen Dysfunction
To evaluate the correlation between endotracheal tube size and incidence of dysfunction of suction lumen of Hi-Lo Evac endotracheal tube in critically ill patients who required mechanical ventilation for more than 48 hours.
- Trial name
- NCT00450476
- Testing
- Hi-Lo Evac Endotracheal Tube
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University Hospital, Alexandroupolis
Respiration, Artificial, Positive-Pressure Respiration
VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU
Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU).
- Conditions
- Respiration, Artificial, Positive-Pressure Respiration, Postoperative Complications (Cardiopulmonary), Postoperative Complications
- Trial name
- VENTICRIT (NCT07646249)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Airway Complication of Anesthesia, Ventilation Therapy; Complications
Structural Modification In Supraglottic Airway Device
The proposed A/Z modification of a supraglottic airway (SGA) incorporates an opening in the SGA body that enables access to the endotracheal tube (ETT) through the body of the SGA without the need of using an exchange catheter…
- Conditions
- Airway Complication of Anesthesia, Ventilation Therapy; Complications, Hypoxia, Hypoventilation
- Trial name
- NCT04498598
- Testing
- A/Z Supraglottic airway
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Ventilation, Mechanical, Ventilation-Associated Pneumonia
Surveillance of Neonatal Endotracheal Tube Colonisation
Babies in neonatal intensive care units (NICUs) sometimes need help breathing using a breathing tube (endotracheal tube, or ETT) connected to a breathing machine (ventilator).
- Trial name
- NETT (NCT07664449)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
The Reduction of Aspiration Rate in Intubated Patients
Effects of Tracheal Tube Size on Pulmonary Aspiration
Fluid leak around the cuff is minimized when the endotracheal tube size is small relative to the size of the trachea. In the current study, the investigators assess the influence of different HVLP endotracheal tube size on fluid…
- Trial name
- NCT01058928
- Testing
- Observation of fluid leakage around tracheal tube cuffs
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Bundang Hospital
Pain, Premature Baby 26 to 32 Weeks
Reducing Pain Levels and Increasing Comfort of Premature Infants During Aspiration
The aim of this study was to investigate the effect of using amigurumi octopus on the pain and comfort of the newborn in premature infants undergoing endotracheal aspiration.
- Conditions
- Pain, Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks, Aspiration
- Trial name
- NCT06306794
- Testing
- crochet octopus
- Volunteers
- 80 people
- Sponsor
- Nurgül Tekin
Respiratory Aspiration of Gastric Content
AuraGainTM and I-Gel® Laryngeal Masks in General Anesthesia for Laparoscopic Cholecystectomy
The standard procedure used for airway control in general anesthesia for LC (laparoscopic cholecystectomy) is endotracheal intubation (EI).
- Trial name
- AILMALC (NCT02925598)
- Testing
- I-gel LMA insertion, AuraGain LMA insertion, ETT insertion
- Volunteers
- 114 people
- Sponsor
- Adiyaman University Research Hospital
Acute Respiratory Distress Syndrome
Open Suction vs. Closed Suction in ARDS
The alveoli tend to collapse in patients with ARDS. Endotracheal aspiration may increase alveolar collapse by decreasing the end-expiratory lung volume.
- Trial name
- NCT05537974
- Testing
- Endotracheal aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Respiration, Artificial
Evaluation of the Versamed iVent in the Transport of Patients Receiving Mechanical Ventilation
The purpose of this study is to evaluate the use of the VersaMed iVent ventilator in the acute care setting, hypothesizing that, in comparison to the standard approach, the use of the VersaMed will facilitate transport and reduce…
- Trial name
- iVent (NCT00652756)
- Testing
- Use of ventilator during patient transport (Versamed iVent), Bag-valve ventilation
- Where
- United States
- Sponsor
- Tufts Medical Center
Endotracheal Intubation, Obesity
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Obese Patients
Airway management in obese patients has to consider that mask ventilation (DMV) risk is increased and difficult tracheal intubation (DTI) risk may be increased too.
- Conditions
- Endotracheal Intubation, Obesity, Desaturation, Ventilation
- Trial name
- Ovesion (NCT03106974)
- Testing
- orotracheal intubation Macintosh Laryngoscope, orotracheal intubation Totaltrack VLM
- Where
- Spain
- Volunteers
- 1,440 people
- Sponsor
- AnestesiaR
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Nursing Caries, Aspiration, Respiratory
- Trial name
- NCT04061083
- Testing
- Smart Cuff Manager, Manometer
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Afyonkarahisar Health Sciences University