Clinical trials: Endodontics
Pain, Postoperative Pain Pathologic Processes Postoperative Complications Signs and Symptoms
Comparative Evaluation of Post Endodontic Pain Following Root Canal Treatment With Two Rotary System: Neolix & Waveone
Today, dentists tend to use rotary systems. Despite the increasing diversity of these systems as well as a few studies on the prevalence of pain after root canal treatment by rotary systems, And in particular, comparing the…
- Trial name
- NCT02768311
- Testing
- neolix rotary system (continuous rotation system), waveone rotary system (reciprocating system), hand files k-files
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Periapical Periodontitis, Bacterial Infections
Adjunctive Steps for Disinfection of Teeth With Primary Endodontic Infections
This study aims to evaluate an endodontic treatment protocol using adjunctive steps for disinfection of teeth with primary endodontic infections.
- Trial name
- NCT03537664
- Testing
- Root canal preparation, Intracanal medication
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo
Symptomatic Irreversible Pulpits
Effect of Emergency Pulpotomy Versus Pulp Extirpation on Anesthetic Efficacy in Endodontic Treatment of Acute Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, and one of the main reasons for seeking emergency dental treatment.
- Trial name
- NCT04599244
- Testing
- emergency pulpotomy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Effect of Manual Glide Path Establishment on Endodontic Postoperative Pain
All patients will be treated in a single session approach regardless of the group. All molars will be anesthetized either through infiltration in case of maxillary molars or inferior alveolar nerve block in case of mandibular…
- Trial name
- NCT05206214
- Testing
- Manual glide path, Mechanical glide path
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Regenerative Endodontics
Regenerative Endodontics Using Different Intracanal Medicaments on Radiographic Outcomes and Periapical MMP-8 Levels
Two-session regenerative endodontic treatment was applied to 20 immature mandibular first molars with symptomatic irreversible pulpitis and symptomatic apical periodontitis.
- Trial name
- NCT05581706
- Testing
- Place the freshly prepared calcium hydroxide in to the root canals, Place the freshly prepared double antibiotic paste in to the root canals, Taking standart periapical radiography with film holder
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ege University
Apical Periodontitis, Insulin Resistance
Serum Pro-Diabetes Inflammation Biomarkers in Patients With Apical Periodontitis.
Inflammation is a common factor of chronic periodontitis and diabetes. However, to date, there is no scientific evidence supporting a causal effect of the inflammation created by apical periodontitis on the onset of insulin…
- Conditions
- Apical Periodontitis, Insulin Resistance, PreDiabetes, Diabetes; Stable
- Trial name
- NCT04824209
- Where
- 2 sites in Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Gagging, Satisfaction, Patient
Controlling Gag Reflex During Endodontic Diagnostic Radiography
Intraoral radiography plays a vital role in endodontic diagnosis and treatment planning. However, many patients experience discomfort during periapical radiographic procedures due to factors such as a pronounced gag reflex and…
- Conditions
- Gagging, Satisfaction, Patient, Endodontic Disease, Anxiety
- Trial name
- NCT07236138
- Testing
- Periapical radiograph will be taken without VR, Periapical radiograph will be taken with VR
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qassim University
Occupational Stress
Apple Watch Evaluation of Endodontics Occupational Stress
This study will enroll approximately 12 endodontists (primary subjects) and approximately 120 patients (secondary subjects) undergoing routine endodontic treatment (primary root canal treatment or retreatment), resulting in…
- Trial name
- NCT07498348
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Apical Periodontitis, Postoperative Pain
Effectiveness of Different Obturation Techniques
Aim: Evaluation of the effect of different obturation techniques on postoperative pain level and radiographic healing on non-surgical endodontic retreatment (NSER) applied in a single visit in teeth with single root canal and…
- Conditions
- Apical Periodontitis, Postoperative Pain, Endodontically Treated Teeth
- Trial name
- NCT06226740
- Testing
- Single Visit Non Surgical Root Canal Treatment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pain Management, Post Endodontic Pain
ORAL AND INTRA - LIGAMENTARY PIROXICAM for Post Endodontic Pain Management
the study find out the effect of oral and intra ligamentary piroxicam on the post endodontic pain . it tell us which one is better among both methods of using piroxicam
- Trial name
- NCT07712991
- Testing
- intra-ligamentary
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Self-Assessment, Self-Perception
E4D Compare Adapted to Preclinical Endodontics
Based on pilot study's promising results, we decided to further investigate the impact of adapting Planmeca Romexis Compare software to evaluate pulpal access preparations on second-year dental students' technical performance…
- Trial name
- NCT06567236
- Testing
- 3D software
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Root Canal Obturation
Measurement of the Clinical and Radiological Performance Impact of the Root Canal Treatment With BioRootTM RCS.
The aim of this retro-prospective Post-Market Clinical Follow-Up (PMCF) study is to collect long term clinical and safety data on root canal obturation after treatment, or retreatment, by BioRootTM RCS.
- Trial name
- BioRoot RCS (NCT05247138)
- Testing
- BioRootTM RCS
- Where
- 9 sites in France
- Volunteers
- 142 people
- Sponsor
- Septodont
Postoperative Pain
Postoperative Pain After the Use of Different Root Canal Sealers
This study evaluated the postoperative pain after the endodontic treatment using AH Plus, Endoseal MTA and EndoSequence BC sealers in root canal obturation.
- Trial name
- NCT03919318
- Testing
- Root Canal Filling Sealers
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Necrotic Pulp
Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File)
this prospective in vivo randomized clinical is to evaluate the post operative pain (incidence ,degree and duration) with multiple full rotation file (protaper next ®) and single full rotation file (Neolix®) in treating maxillary…
- Trial name
- NCT03059290
- Testing
- neolix file
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Endodontically Treated Teeth
"Effect of Sonic Activation Assisted Irrigation and Apical Enlargement on Postoperative Endodontic Pain"
The purpose of this randomized clinical trial is to evaluate the incidence of postoperative pain after retreatment after apical enlargement and sonic activation assisted irrigation.
- Trial name
- NCT04314908
- Testing
- Apical enlargement, Apical enlargement + Sonic Activation Assisted Irrigation, Non Apical enlargement
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Endodontically Treated Teeth
Evaluation the Post Operative Pain of Endodontic Treated Molar Tooth With Race and Reciprocal Systems Among Bandarabbas Patients in 2017
extrusion of infected dentin into the periapical tissue has been suggested as a major source of pain after endodontic treatment.
- Trial name
- NCT03488836
- Testing
- reciproc, race rotary
- Where
- Iran
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Sajad Ansari Fard
Periapical Periodontitis
Encapsulated Acellular System From Mesenchymal Stem Cells for Dental Pulp Regeneration
To evaluate the security and efficacy in the administration of encapsulated acellular system derived from Mesenchymal Stem Cells as a novel regenerative endodontic procedure which to promote the pulpar regenration.
- Trial name
- NCT05599087
- Testing
- Acellular system
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Universidad de los Andes, Chile
Root Canal Infection, Pain
The Effect of Solvent Usage on Post-treatment Pain
No clinical evidence has been yet published regarding the comparison of postoperative pain after removal of the root canal fillings with or without solvent.
- Trial name
- NCT03756363
- Testing
- Non-solvent, Solvent
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Root Canal Treatment
On Previously Root Canal-treated Patients Using an AI Program, Detect the Accuracy of it in the Detection of Root Canal Obturation Quality on CBCT Compared With Conventional PA Radiography, e.g., Voids, Length of Obturation, and Density, and Then do Retreatment if Any Failure is Recorded.
aims to evaluate the accuracy of clinicians (conventional radiograph) compared to cone beam computed tomography (CBCT) and artificial intelligence software's ability to identify the quality of root canal obturation.
- Trial name
- AI (NCT07056998)
- Testing
- root canal retreatment
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tala Ghassan Hassan Odeh
Non-vital Immature Anterior Teeth
Comparison Between Emdogain and Amniotic Membrane as a Scaffold in Endodontic Regeneration of Immature Anterior Teeth
To evaluate the clinical outcomes and cone-beam computed tomography findings of enamel matrix derivative and amniotic membrane in regenerative endodontic treatment of non-vital immature permanent anterior teeth
- Trial name
- NCT07252167
- Testing
- Regenerative endodontic treatment with conventional blood clot technique., regenerative endodontic treatment with emdogain., regenerative endodontic treatment with amniotic membrane
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Al-Azhar University