Clinical trials: Emergency Abdominal Surgery
Surgical Wound
Blood Characteristics and Abdominal Emergency Surgery
After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.
- Trial name
- NCT06028854
- Where
- 2 sites in Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chile
Inguinal Hernia
Predictability of the Ability to Perform an Emergency Stop After Surgery for Inguinal Hernia
Several studies exist on patient performance in drive simulators especially around and after surgery. Recommendations concerning the ability to drive after inguinal hernia are scarce and so far do not offer conclusive results.
- Trial name
- NCT03808012
- Testing
- Braking performance in a brake simulator
- Where
- Germany
- Sponsor
- University Hospital Tuebingen
Post-induction Hypotension
Management of Post-Induction Hypotension in Emergency Abdominal Surgery
The goal of this clinical trial is to compare the efficacy of two vasopressors (norepinephrine vs. ephedrine) in treating hypotension in adult patients (aged 18+, ASA I-III) undergoing general anesthesia for abdominal surgical…
- Trial name
- NCT07259655
- Testing
- Ephedrine (6 mg boluses), Norepinephrine (10 µg boluses)
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- Hopital Charles Nicolle
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Open Abdomen
An Adhesion Reduction Plan in the Management of the Surgical Open Abdomen
The purpose of this study is to determine whether an adhesion reduction plan, consisting of early adhesion prevention and application of a bioresorbable membrane is effective in reducing the severity of adhesions and the…
- Trial name
- NCT01010464
- Testing
- Adhesion Reduction Plan
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Perforated Duodenal Ulcer
Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
ABSTRACT BACKGROUND: Enhanced recovery after surgery (ERAS) protocols have been widely studied in elective abdominal surgeries and have shown better outcomes.
- Trial name
- NCT04431037
- Testing
- Early oral feeding/Enhanced recovery after surgery protocols
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- College of Physicians and Surgeons Pakistan
Acute Abdomen, Emergency Surgery
Primary Cecal Pathologies Presenting as Acute Abdomen
Background: The importance of cecal pathologies lie in the fact that being the first part of large intestine, any disease involving the cecum affects overall functioning of the large bowel.
- Conditions
- Acute Abdomen, Emergency Surgery, Laparotomy, Amoebic Colitis
- Trial name
- NCT03262025
- Testing
- Operated
- Volunteers
- 43 people
- Sponsor
- Jawaharlal Nehru Medical College
Wound Healing, Prevena
Prevena™ Incision Management System vs Conventional Management for Wound Healing
Comparison in abdominal wound healing after contaminated or dirty surgery with incisional negative pressure wound therapy versus standard dressing.
- Conditions
- Wound Healing, Prevena, Dirty Abdominal Surgery, Contaminated Abdominal Surgery
- Trial name
- NCT02892435
- Testing
- incisional negative pressure wound therapy, conventional dressing
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Ospedale Misericordia e Dolce
Cholecystitis, Acute, Cholecystitis; Gangrenous
Risk Factors for Necrotic Cholecystitis During COVID-19 Pandemic.
Gangrenous cholecystitis is the most common complication of acute cholecystitis. Preliminary data showed that COVID-19 patients have a high risk to present necrotic cholecystitis.
- Conditions
- Cholecystitis, Acute, Cholecystitis; Gangrenous, Cholecystitis Suppurative, Covid19
- Trial name
- ChoCO-W (NCT04542512)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poissy-Saint Germain Hospital
Sepsis, Intra-Abdominal Infections
Gelaspan vs Crystalloid Therapy in Sepsis
The goal of this randomized clinical trial is to evaluate whether balanced gelatin solution is more effective and safe than balanced crystalloid solution for perioperative fluid management in adults with sepsis undergoing…
- Trial name
- SPACES (NCT07172451)
- Testing
- Balanced Gelatin Solution, Acetate Ringer's Solution
- Where
- 9 sites in China
- Volunteers
- 318 people
- Sponsor
- Shanghai Zhongshan Hospital
Abdominal Wall Defect, Abdominal Wall Hernia
The Efficacy and Security of the Small Stitch Technique in Emergency Surgery
This study evaluates the abdominal closure technique in emergency surgery. Half of participants will be perform the classic Large Stitch technique, while the other half will undergo the Small Stitch technique.
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Eventration, Evisceration; Operation Wound
- Trial name
- STCU (NCT03765060)
- Testing
- Monomax® 2/0 HR26, Monomax® 1 HR48
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Surgical Wound Dehiscence
Prevention of Fascial Dehiscence With Prophylactic Onlay Mesh in Emergency Laparotomies
Facial dehiscence elicit high morbidity and mortality. This complication may arise in more than 8.5% of high-risk patients. Addressing risk factors and optimizing surgical technique are guarded as mainstay measures for…
- Trial name
- NCT03293862
- Testing
- prophylactic polypropilene mesh, Midline Fascial Closure, vacuum drainage system
- Where
- Brazil
- Volunteers
- 145 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Abdomen
The Role of Laparoscopy in Upper Abdominal Surgical Emergencies in Adults: A Retrospective Observational Study.
Introduction Laparoscopy can be used to diagnose and treat the etiologies of acute abdominal pain. This study aimed to assess laparoscopy's effectiveness in upper gastrointestinal (G.I.T) emergencies regarding intra-and…
- Trial name
- NCT05591495
- Testing
- laparoscopy in upper abdominal surgical emergencies in adults
- Volunteers
- 215 people
- Sponsor
- Zagazig University
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Abdominal Pain
Randomized Study Evaluating the Role of Surgeon-Performed Ultrasound in the Management of the Acute Abdomen
The purpose of this study is to evaluate whether surgeon-performed ultrasound as a supplement to clinical investigation when a patient presents with abdominal pain in the emergency department can improve the management of the…
- Trial name
- NCT00550511
- Testing
- Surgeon-performed ultrasound
- Volunteers
- 800 people
- Sponsor
- Karolinska Institutet
Acute High-risk Abdominal Surgery (AHA)
Early Mobilization Following Emergency Abdominal Surgery
Acute High-risk abdominal surgery (AHA) is associated with high mortality rates, multiple postoperative complications and prolonged duration of hospital admission.
- Trial name
- NCT03662932
- Testing
- Early intensive mobilization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Morten Tange Kristensen PT, PhD
Inguinal Hernia, Acute Appendicitis
The Onset Time of Rocuronium in Emergency and Elective Surgery
Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating.
- Trial name
- NCT02634255
- Testing
- Rocuronium elective surgery, Rocuronium emergency surgery, Propofol
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Abdominal Sepsis, Peritonitis
Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery
Septic shock of intra-abdominal origin is likely due to Gram-negative bacteria or mixed pathogens and associated with high levels of endotoxin.
- Conditions
- Abdominal Sepsis, Peritonitis, Colon Perforation
- Trial name
- NCT01646229
- Testing
- Polymyxin-B hemoperfusion, Control
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Geneva
Emergency General Surgery
STRATA: Surgical Treatment Using Robotic Approach in The Acute Abdomen
Robotic surgery in the UK is now widely used in elective procedures based on evidence that it can improve outcomes, with improved vision and precision for the surgeon resulting in better results and greater rates of minimally…
- Trial name
- STRATA (NCT07850401)
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Portsmouth Hospitals NHS Trust