Clinical trials: Emergencies, open to volunteers
Opioid Use Disorder
Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine
This study aims to develop and pilot test a patient decision aid (PtDA) for emergency department (ED)-initiated buprenorphine treatment for opioid use disorder (OUD).
- Trial name
- NCT07278518
- Testing
- Patient Decision Aid for Opioid Use Disorder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Hyperkalaemia
AI-Enabled ECG Stratification and Timing of Potassium-Lowering Therapy in Patients With Hyperkalemia: A Target Trial Emulation Study
Hyperkalemia is a common and potentially life-threatening electrolyte disorder, yet there is limited evidence guiding the optimal timing of potassium-lowering therapy in routine clinical practice.
- Trial name
- AIDE-K (NCT07307729)
- Testing
- Timely treatment, Delayed treatment
- Volunteers
- 5,000 people
- Sponsor
- National Defense Medical Center, Taiwan
Community-Acquired Pneumonia, Fraility
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on…
- Conditions
- Community-Acquired Pneumonia, Fraility, Hospitalizations
- Trial name
- NCT07442656
- Testing
- Clinical frailty scale, Clinical Frailty Scale (CFS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Surgical Site Infection (SSI)
Rationale of Subcutaneous Levofloxacin Infiltration as an Adjunct for Surgical Site Infection Prevention in Emergency Laparotomy
Surgical site infection (SSI) remains a major cause of postoperative morbidity following emergency laparotomy, particularly in contaminated and dirty/infected abdominal conditions.
- Trial name
- NCT07696819
- Testing
- Levofloxacin
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Sylhet M.A.G.Osmani Medical College
Trauma and Emergency Care
Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a clinical phenomenon caused by the abrupt rupture and bleeding of blood vessels at the surface or base of the brain, which can occur for a number of reasons.
- Trial name
- NCT07252505
- Testing
- Magnesium Sulfate 10 MG/ML
- Volunteers
- 50 people
- Sponsor
- Assiut University
Disaster Planning, Emergency Medical Services
The KAEPacity Study Analyzes Hospital Emergency and Disaster Plans From Hospitals Across Germany to Evaluate How Well Hospitals Are Prepared for Crises and Disasters Organizational Structures Communication Leadership Training Are Examined Within These Plans No Medical Intervention is Performed
Hospital Emergency and Disaster Plans (Krankenhausalarm- und Einsatzplan-KAEP) are a central component of hospital preparedness in Germany.
- Conditions
- Disaster Planning, Emergency Medical Services, Germany
- Trial name
- KAEPacity (NCT07440329)
- Where
- Germany
- Volunteers
- 319 people
- Sponsor
- Lea Kölsch
Caregiver Participation, Emergency Department Presentation
Supporting Caregivers Following Mental Health Emergency Department Visits
The investigators plan to conduct a pilot hybrid effectiveness-implementation type 1 randomized controlled trial comparing 3 arms of varying follow-up intervention.
- Conditions
- Caregiver Participation, Emergency Department Presentation, Safety Plan
- Trial name
- SCFMHEDV (NCT07411300)
- Testing
- Telephone Calls, Automatic MyChart Messages
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Climate-Resilient Disaster Preparedness, Disaster Nursing Education
Climate-Resilient Disaster Preparedness Education to Improve Knowledge and Skills in Nursing Students: A Quasi-Experimental Study
This study aims to evaluate the impact of a structured climate-resilient disaster preparedness education program on undergraduate nursing students' knowledge and practical skills.
- Conditions
- Climate-Resilient Disaster Preparedness, Disaster Nursing Education, Emergency Preparedness in Nursing Students, Nursing Education - Climate Change and Disasters
- Trial name
- CRDP-NurseEd (NCT07139262)
- Testing
- Climate-Resilient Disaster Preparedness Education Program, Standard Nursing Curriculum
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cairo University
Student Education
Virtual Escape Room Education and Triage
This study was planned as a randomized controlled experimental design to determine the effect of triage training given to First and Emergency Aid students via a virtual escape room.
- Trial name
- NCT07181772
- Testing
- virtual escape room, with Power point education
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Complications, Child
Effect of FPCA on Incidence of Emergency Delirium in Children After Surgery
Emergence delirium (ED) stands out as a prevalent postoperative complication among paediatric patients, correlating with extended hospitalization periods, escalated healthcare expenses, and increased incidence of postoperative…
- Conditions
- Postoperative Complications, Child, Family, Emergence Delirium
- Trial name
- NCT06092671
- Testing
- Family-centred perioperative care for anaesthesia
- Where
- China
- Volunteers
- 444 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Trauma (Including Fractures)
Stress in Trauma Patients in Triage Categories 3-5
The aim of this study is to better understand what causes patients the most concern immediately after an injury. We would like to find out how stressed patients are and whether the main causes of stress are pain, fear regarding…
- Trial name
- NCT07811830
- Testing
- Questionnaire and Physical Exam
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- Gabriela Katharina Pomper
Homelessness
Emergency Department Linkage to Care for Patients Experiencing Homelessness
In an effort to improve access to primary care at time of discharge, patients who are homeless will be given either enhanced follow up through a street medicine team or routine follow up in clinic.
- Trial name
- NCT07209072
- Testing
- Street medicine follow up
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Denver Health and Hospital Authority
Artificial Intelligence, Machine Learning
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency…
- Conditions
- Artificial Intelligence, Machine Learning, Microbiology, Emergency Service, Hospital
- Trial name
- ABC (NCT06163781)
- Testing
- Blood culture prediction tool
- Where
- Netherlands
- Volunteers
- 7,584 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Hepatitis C
ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing
Hepatitis C virus (HCV) infection has become the leading fatal infectious disease in the United States. Approximately 75% of individuals who have been infected with HCV are chronically infected with the virus.
- Trial name
- NCT03767231
- Testing
- Xpert HCV Viral Load Finger-stick Point-of-Care test (Cepheid)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Epilepsy, Status Epilepticus
Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus
Status epilepticus (SE) is an acute and critical form of neurological and systemic diseases involving multiple clinical disciplines, with an annual incidence of (20-73) per 100,000 people and a clinical case fatality rate of 20%.
- Trial name
- NCT06966830
- Testing
- Lacosamide (LCM)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Acute Headache, Migraine
High- vs Standard-Dose Intravenous Magnesium for Acute Headache
Headache is one of the most common reasons for consultation in emergency departments and represents a significant cause of disability, particularly in patients with migraine and other primary headache disorders.
- Conditions
- Acute Headache, Migraine, Tension-type Headache, Cluster Headache
- Trial name
- MAGHEAD (NCT07779486)
- Testing
- Magnesium Sulfate 2 grams, Magnesium Sulfate 4 G, Paracetamol 1 g
- Where
- Tunisia
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Emergency Medicine, POCUS
Point-of-Care Ultrasound for Diagnosing Abdominal Pain in the Emergency Department
The goal of this clinical trial is to learn if adding an abdominal ultrasound scan to the standard examination helps emergency physicians make a correct diagnosis in adults with acute abdominal pain in the emergency department.
- Conditions
- Emergency Medicine, POCUS, Abdominal Pain (AP), Acute Abdominal Pain
- Trial name
- AbdoPOCUS (NCT07849569)
- Testing
- Point of care ultrasound
- Where
- 3 sites in Denmark
- Volunteers
- 508 people
- Sponsor
- University of Aarhus
Cancer, Cancer Remission
Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location
Patients being followed for cancer account for 2.8% of emergency admissions in France. An acute episode that triggers a visit to the emergency department may be related to the progression of the disease, or to complications of…
- Trial name
- COVER (NCT06834646)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oncologic Complications and Emergencies
Ultrasound-guided Peripheral Intravenous Catheter Placement in an Oncologic Emergency Department - a Prospective, Randomized Controlled Trial of Catheter Lengths
To learn about the effects of the length of the catheter on the failure and success rate of USIV placement.
- Trial name
- NCT06217783
- Testing
- Introcan Safety IV Catheter
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- M.D. Anderson Cancer Center