Clinical trials: Emergence Delirium in Pediatric Anesthesia
Emergence Agitation
Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan.
- Trial name
- NCT06218680
- Testing
- Propofol, Normal saline
- Where
- Thailand
- Volunteers
- 134 people
- Sponsor
- Khon Kaen University
Postoperative Pain, Emergence Delirium
Effect of Preoperative Fasting Duration on Postoperative Pain and Emergence Agitation in Pediatric Patients Undergoing Urogenital Surgery
This study aims to evaluate the effect of preoperative fasting duration on postoperative pain and emergence agitation in pediatric patients undergoing urogenital surgery.
- Conditions
- Postoperative Pain, Emergence Delirium, Emergence Agitation
- Trial name
- NCT07552259
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postoperative Nausea, Postoperative Vomiting
Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in Children Undergoing Endoscopic Adenoidectomy in General Anesthesia
The study has been designed as a prospective randomized clinical trial. Due to the use of a bispectral (BIS) monitor in the interventional arm, the study will not be blinded for the anesthetist.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Emergence Delirium
- Trial name
- NCT04466579
- Testing
- BIS monitor, Standard care
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Delirium
Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children
The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of anesthesia.
- Trial name
- NCT02707016
- Testing
- Sevoflurane 8%, Sevoflurane 5%
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergency Delirium, Postoperative Delirium (POD)
Comparison of IV Dexmedetomidine Versus Clonidine Versus no Alpha 2 Agonist on Emergency Delirium, PACU Length of Stay and Time to Hospital Discharge in Children Undergoing (Adeno)Tonsillectomy: a Prospective Observational Study
Emergence delirium (ED) is a frequent complication in children undergoing general anesthesia, particularly following ENT procedures such as adenotonsillectomy.
- Conditions
- Emergency Delirium, Postoperative Delirium (POD), Adenotonsillectomy, Tonsillectomy
- Trial name
- CLONIDEX (NCT07913308)
- Testing
- Intravenous dexmedetomidine, Intravenous clonidine, Standard Anesthetic Care Without Alpha-2 Agonist
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Otitis Media
Study Using Dexmedetomidine to Decreases Emergence Delirium in Pediatric Patients
The purpose of this study is to evaluate the use of intranasal dexmedetomidine to reduce the incidence of emergence delirium during general sevoflurane anesthesia in a pediatric population receiving pressure equalization tubes in…
- Trial name
- PED-DEX (NCT00778063)
- Testing
- dexmedetomidine, saline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Emergence Agitation
Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery
The study is conducted to evaluate the effects of dexmedetomedine in subtenon's block in conjunction to general anesthesia under sevoflurane anesthesia on emergence agitation, intraoperative hemodynamic stability, postoperative…
- Trial name
- NCT04485273
- Testing
- Laryngeal Mask Airway, Sevoflurane, Subtenon's Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Postoperative Agitation, Emergence Delirium, Anesthesia
Impact of Neuromonitoring on Postoperative Agitation in Pediatric General Anesthesia
Postoperative agitation is frequently observed in the pediatric patient group following general anesthesia. The exact cause of this agitation has not been clearly determined; however, it may be associated with various factors…
- Trial name
- NCT07243990
- Testing
- dsa intervention group, Traditional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sakarya University
Postoperative Pain, Preoperative Anxiety
Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery
The goal of this observational study is to learn if preoperative anxiety levels can predict the quality of early postoperative recovery, pain intensity, and the occurrence of emergence delirium in pediatric patients aged 2 to 7…
- Conditions
- Postoperative Pain, Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia, Urogenital Diseases
- Trial name
- NCT07343388
- Testing
- Standardized Perioperative Management and Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Aydin Adnan Menderes University
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Emergence Delirium (Derlenme Deliryumu)
Brain Monitors to Reduce Child Confusion After Anesthesia
The goal of this clinical trial was to learn if using a brain monitor to adjust anesthesia (sleep medicine) during surgery could prevent emergence delirium (severe confusion and agitation upon waking) in children aged 2 to 12…
- Trial name
- NCT07826559
- Testing
- BIS-Guided Anesthesia, Standard Care Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Delirium, Pediatric Anesthesia
Inflammatory Biomarkers and Postoperative Delirium in Pediatric Circumcision
Postoperative delirium may occur in children after general anesthesia, even following short procedures such as circumcision. Preoperative systemic inflammation has been associated with postoperative delirium in adults, but data…
- Conditions
- Postoperative Delirium, Pediatric Anesthesia, Inflammatory Biomarkers
- Trial name
- NCT07323485
- Testing
- Measurement of Preoperative Inflammatory Biomarkers
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Delirium, Pediatric Disorder
Emergence Delirium in Children for Magnetic Resonance Imaging
Sedation or anaesthesia is necessary to be able to perform magnetic resonance imaging (MRI) on children who cannot keep still or are uncooperative, and thus the targets of maximum patient safety, successful imaging, and the…
- Conditions
- Delirium, Pediatric Disorder, Anesthesia
- Trial name
- NCT04816344
- Testing
- Outpatient Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Emergence Agitation
Effect of Lollipop on Emergence Delirium in Pediatric Patients Undergoing General Anesthesia
This study aims to evaluate the effectiveness of lollipop administration after surgery in reducing emergence agitation in pediatric patients undergoing anesthesia with sevoflurane at RS Ngoerah.
- Trial name
- LOLLIPOP-ED (NCT07571707)
- Testing
- Lollipop
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Udayana University
Emergence Delirium in Pediatric Anesthesia
The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn Patients
The aim of this study is to compare the effects of dormicum-ketamine versus dexmedetomidine on postoperative emergence delirium in pediatric patients undergoing deep sedation for burn-related procedures
- Trial name
- NCT07519863
- Testing
- Midazolam + Ketamine, Dexmedetomidine (DEX)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergence Delirium, Intravenous Anesthesia
Sevoflurane and Intravenous Anesthesia in Hypospadias Repair
Emergence agitation (EA), a phenomenon observed at the time of recovery from general anesthesia (GA).The cause of ED appears to be multifactorial in origin.
- Conditions
- Emergence Delirium, Intravenous Anesthesia, Sevoflurane
- Trial name
- NCT06396468
- Testing
- sevoflurane, propofol
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Emergence Delirium, Dexmeditomidine
Intravenous Dexmedetomidine for Emergence Delirium in Pediatric Patient
Various pharmacological interventions in peri-operative period have been used in literature to prevent ED which include use of propofol, fentanyl, ketamine, clonidine, midazolam and dexmedetomidine etc (5).
- Trial name
- NCT05813106
- Testing
- Dexmedetomidine Hydrochloride, normal saline
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Security Forces Hospital