Clinical trials: Electrocardiography (ECG)
Ventricular Arrythmia, Ischemic Cardiomyopathy
Multicentre Investigation of Novel Electrocardiogram Risk Markers in Ventricular Arrhythmia Prediction
This is a prospective open label single blinded multi-centre observational study involving a study group of patients already undergoing implantable cardioverter-defibrillator (ICD)(including Cardiac resynchronisation therapy…
- Trial name
- MINERVA (NCT03022487)
- Where
- 8 sites in United Kingdom
- Volunteers
- 395 people
- Sponsor
- University of Leicester
Cystic Fibrosis
An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participants
The purpose of this study is to evaluate the effect of Vanzacaftor (VNZ) on QTcF, as well as the pharmacokinetic (PK), safety, and tolerability of VNZ in healthy participants.
- Trial name
- NCT05867147
- Testing
- Vanzacaftor, Moxifloxacin
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Anesthetized Ventilated Patients
Pulse Transit Time in Anesthetized Patients: Blood Pressure or Cardiac Output as Measured With NICOM Monitor
Pulse transit time (PuTT) - the time between R wave on ECG and initiation of upstroke in the peripheral arterial waveform - described in the previous studies as value that reflects changes in both blood pressure and blood volume.
- Trial name
- PuTT-NICOM (NCT01259687)
- Testing
- Non-invasive cardiac output monitoring
- Where
- 2 sites in Israel
- Volunteers
- 63 people
- Sponsor
- Carmel Medical Center
In Vitro Fertilization, Estradiol
Impact of Supraphysiological Estradiol on ECG in IVF Patients
This prospective observational study aimed to evaluate the effects of supraphysiological estradiol (E2) levels, induced by gonadotropin therapy during IVF, on cardiac electrophysiological parameters.
- Conditions
- In Vitro Fertilization, Estradiol, Cardiac Electrophysiology, Electrocardiography (ECG)
- Trial name
- NCT07007416
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Konya City Hospital
Cardiomyopathy
AI-SCREENDCM Decentralized Clinical Trial - Pilot Study
The purpose of this study is to assess the feasibility and impact of screening FDR of DCM probands using a mobile ECG with the ability to transmit the ECG for cloud-based AI analysis to detect reduced left ventricular ejection…
- Trial name
- NCT06609174
- Testing
- KardiaRx ECG Screening and AI interpretation of ECG
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Mayo Clinic
Individuality, Perioperative/Postoperative Complications
Perioperative Heart Rate Variability Analysis in Realtime
This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent…
- Conditions
- Individuality, Perioperative/Postoperative Complications, Heart Rate and Rhythm Disorders, Surgical Complications From General Anesthesia
- Trial name
- PHERVR (NCT02761031)
- Where
- Austria
- Volunteers
- 88 people
- Sponsor
- Medical University of Vienna
Arrhythmia in Children
Electrocardiography for the Automatic Analysis of Arrhythmia in Children
The project is a direct response to the identified lack of ECG diagnostic solutions dedicated to children. There are several tools for automatic ECG signal analysis in adults, but these cannot be used in the diagnosis of heart…
- Trial name
- NCT05272722
- Testing
- ECG,
- Where
- Poland
- Volunteers
- 675 people
- Sponsor
- Medical University of Warsaw
Hepatitis C
VX-950-TiDP24-C136 - A Trial to Evaluate the Effect of Telaprevir (TVR) on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy Volunteers
The purpose of this study is to evaluate the effect of telaprevir on the results of electrocardiograms in healthy volunteers. An electrocardiogram is an electric recording of the heart.
- Trial name
- NCT00973388
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tibotec BVBA
Long QT Syndrome, Cardiac Repolarization
Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Background. In congenital long QT syndrome type 1 (LQT1), episodes of ventricular tachycardia are usually triggered by exercise and can be prevented in most patients by beta-blocker therapy.
- Trial name
- NCT00588965
- Testing
- Propranolol LA
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Proficiency in Computer Interpretation of the ECG
Computer Interpretation of the ECG Raising Awareness CIERA Trial
Background: Practice guidelines require emergency and critical care nurses (ECC) to be skillful in ECG and cardiac monitoring. Evidence suggests that nurses' proficiency is still inadequate with this regard.
- Trial name
- CIERA (NCT07595601)
- Testing
- Flyer, face-to-face lecture, Online lecture
- Where
- Jordan
- Volunteers
- 268 people
- Sponsor
- University of Jordan
Periprocedural Myonecrosis
Intracoronary Electrocardiogram (ECG) and Myonecrosis After Bifurcation Stenting
The coronary bifurcation lesions pose a therapeutic problem with high rates of periprocedural complications, higher rates of in-stent restenosis and stent thrombosis.
- Trial name
- COSIBRIA&CO (NCT01268228)
- Where
- 3 sites in Bulgaria, Poland
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University National Heart Hospital
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes
This observational study will evaluate the cardiovascular effects of sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) in Korean adults with type…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases, Stage B Heart Failure
- Trial name
- NCT07770737
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Dongtan Sacred Heart Hospital
Bradycardia
Analysis in the EMERGEncy Between TransVenous Cardiac PACIng Guided by Fluoroscopy Versus Echocardiogram
A lot of questions about use of temporary transvenous pacing still remain obscure and there is no effective comparison between use of fluoroscopy versus electrocardiogram/echocardiogram in patients with bradicardias.
- Trial name
- EMERG-TV-PAC (NCT03037333)
- Testing
- Transvenous cardiac pacing guided by fluoroscopy, Transvenous cardiac pacing guided by ECG/ECHO
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation, Atrial Function
Multi-Channel Esophageal ECG Signal Classification
This study is designed to prove new methods to enable the automated analysis of esophageal electrocardiography (eECG) signals in long-term measurements as well as the detection of atrial fibrillation.
- Conditions
- Atrial Fibrillation, Atrial Function, Arrhythmias, Cardiac, Atrial Premature Complexes
- Trial name
- MC-EECG (NCT02541175)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hemodynamic Effects of Energy Drink, Electrocardiograph Effects of Energy Drinks
Evaluation of Energy Drink Consumption on ECG and Hemodynamic Parameters in Young Healthy Volunteers
This study is designed as a safety assessment to determine the cardiac and hemodynamic effects of overuse of energy drinks in healthy individuals through ECG, heart rate (HR) and blood pressure measurements.
- Trial name
- NCT02023723
- Testing
- Energy Drink, Active Control
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Medical Oncology
Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole
Characterize the safety, tolerability, ECG effects, pharmacokinetics and immunogenicity of anetumab ravtansine given as single agent and after inhibition of CYP3A4 and P-gp by concomitant administration of itraconazole in…
- Trial name
- NCT02824042
- Testing
- Anetumab ravtansine (BAY94-9343), Itraconazole
- Where
- 18 sites in United States, Australia and 4 more
- Volunteers
- 63 people
- Sponsor
- Bayer
Heart Arrest, Arrhythmias, Cardiac
Cardiac Arrest Post-Discharge ECG Monitoring
The primary aim is to conduct a prospective observational cohort study to analyze the incidence of serious arrhythmic events that occur within 14 days after hospital discharge in patients who had been hospitalized for cardiac…
- Conditions
- Heart Arrest, Arrhythmias, Cardiac, Electrocardiography
- Trial name
- CArPEM (NCT05337371)
- Testing
- ECG patch (Philips ePatch® 2.0)
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Sleep Disorders, Sleep Apnea
Electrocardiography Data Analysis in Sleep Disorders
The objective of this study is to determine if a non-invasive technique, using an innovative analysis of electrocardiogram (ECG) data, would allow for detection of respiratory events during sleep and discrimination between…
- Conditions
- Sleep Disorders, Sleep Apnea, Sleep Disordered Breathing
- Trial name
- Holter (NCT02188498)
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Disease
Analysis of Surface EKG Signals to Identify Myocardial Dysfunction in Patients at Risk for Coronary Artery Disease
1. The MyoVista device is capable of detecting surface electrocardiogram signals and sensitive in detecting coronary artery disease compared to traditional computed tomography angiography (CTA) 2.
- Trial name
- NCT02560168
- Testing
- MyoVista device, Computed tomographic coronary angiography, Transthoracic Echocardiography
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Heart Disease, Electrocardiograph
DigitHeart Echo Study
Eligible patients will be interviewed by research staff to explain the trial design and rationale. Written informed consent will be obtained from patients who voluntarily agree to participate.
- Conditions
- Heart Disease, Electrocardiograph, Echocardiography
- Trial name
- DigitHeart-SHD (NCT07558109)
- Testing
- echocardiography
- Where
- Hong Kong
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong