Clinical trials: Elderly Patients
Adrenal Suppression, Hemodynamic Instability
THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients
Compare the efficacy and safety of closed-loop target controlled infusion of propofol or etomidate at general anesthesia in geriatric patients
- Trial name
- NCT02111265
- Testing
- Remifentanil, Cisatracurium, Sufentanil
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Idiopathic Interstitial Pneumopathy/Pneumopathy Interstitial Diffuse, Paediatric and Adult Patients
RaDiCo PID Cohort (RaDiCo-ILD Cohort in English)
The main objective is to describe the phenotypic features of the paediatric and adult patients with Idiopathic Interstitial Pneumopathy/Pneumopathy Interstitial Diffuse (IIP/PID), at diagnosis and during the follow-up.
- Trial name
- RaDiCo-PID (NCT04238871)
- Where
- 2 sites in France
- Volunteers
- 1,600 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cognitive/Functional Effects, Colorectal Cancer
Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer
This randomized phase III trial studies how well combination chemotherapy plus bevacizumab with or without oxaliplatin works in treating older patients with colorectal cancer that has spread to other places in the body.
- Conditions
- Cognitive/Functional Effects, Colorectal Cancer, Neurotoxicity
- Trial name
- NCT01279681
- Testing
- bevacizumab, capecitabine, fluorouracil
- Volunteers
- 32 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pulmonary Disease, Cardiac Disease
Technology Assisted Physical Activity Among Hospitalised Medical Patients
Research show that inactivity during hospitalization is the norm and that the negative effects on muscle mass and the fitness of the patient will take a long time and hard work to recover afterwards.
- Conditions
- Pulmonary Disease, Cardiac Disease, Geriatric Disease
- Trial name
- TAPAS-2 (NCT04555330)
- Testing
- Physical activity measurement, Visual Feedback
- Where
- Denmark
- Volunteers
- 354 people
- Sponsor
- Marius Henriksen
Hypertension, Chronic Kidney Disease.
Effect of Eplerenone in Elderly Hypertensive Early Stage Chronic Kidney Disease (CKD) Patients
The purpose of this study is to determine whether eplerenone is effective in the treatment of blood pressure, heart function, renal function in elderly hypertensive stage1 (eGFR>=90ml/min/1.73m2) and stage2 (eGFR…
- Trial name
- NCT01302236
- Testing
- Eplerenone
- Sponsor
- Jichi Medical University
Carcinoma, Non-Small-Cell Lung
Comprehensive Geriatric Assessment and Complications Following Lung Resection for Lung Cancer
schema : Prospective prognostic study The main objective is to study the value of the Comprehensive Geriatric Assessment in predicting the risk of post operative complications after lung resection for cancer.
- Trial name
- OPERAGE (NCT01956331)
- Where
- 25 sites in France
- Volunteers
- 302 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
Multiple Myeloma, Hematologic Diseases
Comparison of Geriatric Screening Methods in Newly Diagnosed Multiple Myeloma Patients
The purpose of this study is to compare clinical judgment and comprehensive geriatric assessment as screening tools for optimization of treatment for newly diagnosed elderly multiple myeloma patients.
- Trial name
- COMPASS (NCT02918695)
- Where
- 20 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Renal Insufficiency
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Trial name
- BCDE (NCT00847275)
- Testing
- Exclusive nephrology follow-up, Geriatric follow-up
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Nantes University Hospital
Lung Cancer
Weekly Topotecan in the First-line Treatment of Elderly Patients With Small Cell Lung Cancer
In this phase II trial, we will evaluate the weekly schedule of topotecan in the first-line treatment of elderly and/or poor performance status patients with extensive stage small cell lung cancer.
- Trial name
- NCT00193401
- Testing
- Topotecan
- Volunteers
- 40 people
- Sponsor
- SCRI Development Innovations, LLC
Cataract
Patient Participation in Free Cataract Surgery
Age-related cataracts remain the leading cause of treatable blindness in China. The prevalence of cataract blindness continues to climb due to the expanding elderly subpopulation.
- Trial name
- NCT02633865
- Where
- China
- Volunteers
- 883 people
- Sponsor
- Sun Yat-sen University
Delivery of Health Care, Health Services
The COPACC Study: Utilization, Health and Economic Evaluation of a Community-Based Primary Care Geriatric Hub at Whampoa
This study evaluates the Community for Successful Ageing (ComSA) Patient-Centered Medical Home (PCMH), a model of community-based primary care geriatric hub at Whampoa, Singapore.
- Conditions
- Delivery of Health Care, Health Services, Costs and Cost Analysis, Quality of Life
- Trial name
- NCT04594967
- Testing
- Patient-centred care home (PCMH)
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Geriatric Education and Research Institute
Diabetes
The Effect of Clinic Visit Audio Recordings for Self-management in Older Adults
The objective of this study is to conduct a multisite trial evaluating the impact of adding an audio recording of clinic visits (AUDIO) to usual care in older adults with multimorbidity, including diabetes, compared to After…
- Trial name
- REPLAY (NCT05824572)
- Testing
- Clinic visit audio recordings for self-management in older adults, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 336 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Delirium in Old Age
Quality Contract: Prevention of Postoperative Delirium in the Care of Older Patients (QV-POD-2)
The project "QV-POD-2" is a prolongation based on "QV-POD-1", which was a quality contract program of the IQTIG - Institute for Quality and Transparency in Health Care.
- Trial name
- NCT04355195
- Where
- 2 sites in Germany
- Volunteers
- 18,100 people
- Sponsor
- Charite University, Berlin, Germany
Perioperative Neurocognitive Dysfunction
Biomarkers and Risk Factors for Perioperative Neurocognitive Dysfunction in Elderly Patients
Basic information and biological samples of patients were collected preoperatively and intraoperatively, and patients were divided into case and control groups by cognitive function assessment postoperatively, and risk factors…
- Trial name
- NCT06044207
- Testing
- Pittsburgh sleep quality index, Self-rating depression scale, Montreal Cognitive Assessment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Jinan Central Hospital
Multi Drug Resistant Department, Multi Drug Resistant Bacteria
Testing Carriage of Resistant Bacteria Using Swabs on Surfaces and Staff in a Complex Nursing Unit for Patients with Resistant Bacteria
Impact of Care Team and Surfaces on the Spread of Resistant Bacteria in a Specialized Complex Nursing Unit for MDR Pathogen Carriers Background Multi-drug resistant (MDR) bacteria present a severe clinical and epidemiological…
- Trial name
- NCT06696144
- Testing
- Skin swabs for multi drug resistant bacteria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Pain
Pharmacokinetic Study of Paracetamol in Patients Over 80 Years Hospitalized to an Acute Geriatric Ward
The goal of this exploratory study is the characterization of the pharmacokinetic (PK) profile of paracetamol in older patients and the specific PK (pharmacokinetic) variables associated with plasma exposure in this population.
- Trial name
- NCT03617471
- Testing
- Venopuncture for PK profiling
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Heart Failure, Obstructive Sleep Apnea
CPAP and Physiotherapy for Heart Failure and Sleep Apnea in the Elderly
This study evaluates whether adding physiotherapy (including herbal medicine, acupuncture, and Tuina massage) to standard continuous positive airway pressure (CPAP) therapy can provide superior benefits compared to CPAP alone for…
- Trial name
- NCT07061171
- Testing
- Continuous Positive Airway Pressure, Herbal Decoction, Acupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Weihua Peng
HIV-1-infection, CD4+ T Lymphocytopenia
Pyridostigmine as Immunomodulator in People Living With HIV
Human immunodeficiency virus (HIV) infection is characterized by persistent immune activation and a constant turnover of T cells. This leads to a precipitous fall in the number of T cells, as well as to an early immunosenescence.
- Conditions
- HIV-1-infection, CD4+ T Lymphocytopenia, Immune Deficiency, Immuno-senescence
- Trial name
- NCT03312244
- Testing
- Pyridostigmine Bromide
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Esophageal Cancer (EsC), Postoperative Pulmonary Complications (PPCs)
Effect of VExUS Score on Postoperative Pulmonary Complications in Elderly Patients
Brief Summary This clinical trial aims to evaluate whether perioperative goal-directed fluid therapy (GDFT) targeting a venous excess ultrasound (VExUS) score of 1 can reduce postoperative pulmonary complications (PPCs) in…
- Trial name
- NCT07691944
- Testing
- VExUS Score-Guided Intraoperative Goal-Directed Fluid Therapy
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Healthy Ageing
Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors
As people age, it can become harder to stay active and independent, especially when dealing with fatigue, joint pain, or other health problems.
- Trial name
- NCT07460609
- Testing
- Blood Flow Restriction Training Exercise, Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor University
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