Clinical trials: Efficacy
Emotion Regulation, Self Efficacy
Skills Video Intervention for Chinese/Chinese Americans
This is a study that aims to test a coping skills intervention delivered via brief animated videos for Chinese and Chinese American college students.
- Conditions
- Emotion Regulation, Self Efficacy, Acceptability of Health Care
- Trial name
- NCT06024083
- Testing
- Dialectical Behavior Therapy skills video intervention
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Caregiver Burden, Depressive Symptoms
Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong
The goal of this cluster randomized controlled trial study is to compare the effectiveness of a novel psychosocial intervention based on Cognitive Behavioral Therapy, lifestyle intervention and effective communication skills in…
- Conditions
- Caregiver Burden, Depressive Symptoms, Quality of Life, Self Efficacy
- Trial name
- NCT06473012
- Testing
- Cognitive Behavioral Therapy for Caregivers of Older Adults, Control intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pressure Ulcers, Bedsores, Decubitus Ulcer, Nursing Education
The Effect of Gamified Metaverse-Based Training on Nursing Students' Self-Efficacy and Metaverse Perception Regarding Pressure Injury Management
Introduction: Pressure ulcers are a largely preventable clinical problem that negatively impacts the quality of patient care and constitutes a significant economic burden for healthcare systems.
- Conditions
- Pressure Ulcers, Bedsores, Decubitus Ulcer, Nursing Education, Gamification, Self-Efficacy
- Trial name
- NCT07395284
- Testing
- Gamified metaverse-based educational application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Safety, Efficacy
Intrastromal Injection of Fluconazole in Treatment of Fungal Keratitis
This study aimed to evaluate the Safety and the Effectiveness of Intrastromal Injection of Fluconazole in The Treatment of Fungal Keratitis.
- Conditions
- Safety, Efficacy, Intrastromal Injection, Fluconazole
- Trial name
- NCT07557966
- Testing
- Topical fluconazole eye drops, Intrastromal injection of fluconazole
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Ulcerative Colitis, Efficacy, Self
Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis
Endocopic remission rates of moderate to severe ulcerative colitis are low. Biologics including Vedolizumab, infliximab, and adalimumab are effective in induction and maintainence of ulcerative colitis.
- Conditions
- Ulcerative Colitis, Efficacy, Self, Biologics, Mesalazine
- Trial name
- NCT05205603
- Testing
- Infliximab, Vedolizumab, Mesalazine
- Where
- 11 sites in China
- Volunteers
- 438 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Dementia, Alzheimer Disease
Learning Skills Together Family Caregiver Complex Intervention
Learning Skills Together (LST) is a 6-week psychoeducational intervention focused on complex care (nursing) tasks completed by family caregivers to persons living with Alzheimer's Disease and related dementias.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burden, Self Efficacy
- Trial name
- LST (NCT05846984)
- Testing
- Learning Skills Together Intervention, Caregiver Healthy Living Intervention
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Alzheimer Disease, End of Life
Palliative Care Education in Assisted Living for Dementia Care Providers (PCEAL-DCP)
The palliative care education in assisted living for dementia care providers (PCEAL-DCP) is a 4-week intervention (once a week for 1.5 hours, a total of 6 hours) for licensed nurses, administrators and dementia care coordinators…
- Conditions
- Alzheimer Disease, End of Life, Caregiver Burden, Caregiver Burnout
- Trial name
- PCEAL-DCP (NCT06722352)
- Testing
- Palliative Care Training
- Where
- 2 sites in United States
- Volunteers
- 792 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Complication Rate, Efficacy and Safety
Efficacy of Thermal Ablation Combined With Antithyroid Drugs in the Treatment of Primary Hyperthyroidism
Hyperthyroidism is a clinical syndrome caused by excessive production of thyroid hormones, leading to accelerated metabolism and increased excitability of multiple organ systems.
- Conditions
- Complication Rate, Efficacy and Safety, Hyperthyroidism/Thyrotoxicosis, Cure Rate
- Trial name
- NCT07557810
- Testing
- thermal ablation combined with antithyroid drug therapy
- Where
- China
- Volunteers
- 454 people
- Sponsor
- Chinese PLA General Hospital
Safety, Efficacy
Safety and Efficacy of Distal Radial Access (SAFE-BOX)
A Prospective Registry to assess the Safety and Efficacy of Distal Radial Approach
- Trial name
- NCT05776550
- Where
- South Korea
- Volunteers
- 3,600 people
- Sponsor
- Yonsei University
Lifestyle, Healthy, Sleepiness
Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents
The purpose of this study is to determine whether personalized lifestyle coaching minimizes the negative impact of circadian disruption on performance and recovery in emergency medicine physician trainees during night shifts.
- Conditions
- Lifestyle, Healthy, Sleepiness, Alertness, Shift-Work Related Sleep Disturbance
- Trial name
- NCT06015646
- Testing
- Personalized lifestyle coaching and educational handout, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Safety, Efficacy
Bilateral Peribulbar Block for Cataract Surgery
This study aims to evaluate the safety and efficacy of bilateral peribulbar block for cataract surgery.
- Conditions
- Safety, Efficacy, Bilateral, Peribulbar Block
- Trial name
- NCT07000669
- Testing
- Bilateral peribulbar block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Digital Addiction, Art Therapy
The Effect of Art-Based Nursing Intervention Helping to Develop Healthy Digital Habits on Digital Addiction, Cyberbullying and Self-Efficacy in Adolescents
In today's world where digital technologies are integrated into every aspect of life, adolescents' unhealthy and uncontrolled use of digital media causes important psychosocial problems such as digital addiction and…
- Conditions
- Digital Addiction, Art Therapy, Cyberbullying, Self Efficacy
- Trial name
- NCT07123194
- Testing
- An Arts-Based Nursing Intervention Program to Help Develop Healthy Digital Habits
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intermediate-to-High-Risk Mantle Cell Lymphoma, the Efficacy and Safety
The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL
A Single-Arm, Prospective Clinical Study Evaluating the Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined with Obinutuzumab in the First-Line Treatment of Newly Diagnosed Intermediate-to-High-Risk Mantle Cell Lymphoma
- Trial name
- NCT07548255
- Testing
- Sonrotoclax, Zanubrutinib Combined with Obinutuzumab
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Ruijin Hospital
Laughter Yoga, Perceived Stress
LaughterYogaStress
It is important for students to develop effective coping behaviors to manage stress, as this contributes to the formation of a positive professional identity.
- Conditions
- Laughter Yoga, Perceived Stress, Self-Efficacy, Nursing Students
- Trial name
- Laughter yoga (NCT07540039)
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
ABPA, Biologics
A Cohort Study of the Efficacy and Safety of Biologics in Patients With ABPA
To evaluate the efficacy and safety of biological agents in patients with allergic bronchopulmonary aspergillosis.
- Conditions
- ABPA, Biologics, Allergic Bronchopulmonary Aspergillosis (ABPA), Cohort Study
- Trial name
- NCT07362693
- Testing
- Biologic Agent
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Qianfoshan Hospital
Postoperative Pain, Quality of Recovery (QoR-15)
MAG-PAIN - MAGnesium for Postoperative Analgesia In the Newly Delivered
The study aims to investigate whether a commonly used medicine, magnesium, can help reduce pain after a Caesarean section. A total of 150 participants will be included.
- Conditions
- Postoperative Pain, Quality of Recovery (QoR-15), Pain Prediction, Magnesium Sulfate
- Trial name
- MAG-PAIN (NCT07528612)
- Testing
- Magnesium group
- Volunteers
- 150 people
- Sponsor
- Region Halland
Antiepileptic Efficacy and Safety, Brain Injuries
Prophylactic Anti-epileptic Regimen in Traumatic Brain Injury
To evaluate the effectiveness and safety of anti-epileptic drugs in the prevention of early and late post-traumatic seizures among patients with trauma brain injury
- Trial name
- NCT07535736
- Testing
- Anti-Epileptic
- Volunteers
- 70 people
- Sponsor
- Assiut University
Immunization, Efficacy
GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose
The investigators are evaluating whether 15-26 year old males and females need a 3rd dose of the human papillomavirus (HPV) vaccine, or whether 2 doses provide similar protection as 3 doses from the 9 types of HPV that it…
- Conditions
- Immunization, Efficacy, Human Papilloma Virus
- Trial name
- NCT03943875
- Testing
- 9-valent HPV vaccine, 2 dose efficacy, 9-valent HPV vaccine, 3 doses standard timing
- Where
- United States
- Volunteers
- 767 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Nutrition, Healthy, Knowledge, Attitudes, Practice
Pilot Study of Capacity-oriented Intervention to Promote Food Security and Diet Quality Among Hispanics/Latinos
Despite a large proportion exhibiting cardiovascular disease risk factors and experiencing food insecurity, U.S. Hispanics/Latinos demonstrate low cardiovascular mortality, which may indicate existing capital (e.g., assets)…
- Conditions
- Nutrition, Healthy, Knowledge, Attitudes, Practice, Self Efficacy
- Trial name
- NCT05623202
- Testing
- Multi-level behavior-change intervention to strengthen food- and diet-related capital to promote food security and diet quality among low-income Hispanic/Latino adults
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University