Clinical trials: Effectiveness of Essential Oil
PONV
Aromatherapy Treatment With Lavender Essential Oil to Reduce Post-Operative Nausea and Vomiting (PONV)
The aim of this study is to evaluate the effectiveness of aromatherapy through the use of inhaled Lavender oil in reducing patients' nausea during the post-operative period.
- Trial name
- Leo-PONV (NCT07176676)
- Testing
- Lavanda Angustifolia essential oil, Usual Care
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Effectiveness of Chlorohexidine, Effectiveness of Essential Oil
Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients
The goal of this clinical trial is to evaluate and compare the antiplaque efficacy and patient reported outcome of three commonly used antiseptic mouthwashes - Chlorhexidine (CHX), Cetylpyridinium Chloride (CPC), and Essential…
- Conditions
- Effectiveness of Chlorohexidine, Effectiveness of Essential Oil, Effectiveness of Cetylpyridinium Chloride
- Trial name
- NCT07490873
- Testing
- Chlorohexidine 0.12% mouthwash, Cetylpyridinium chloride 0.05% mouthwash, Essential Oil mouthwash
- Where
- Iraq
- Volunteers
- 20 people
- Sponsor
- University of Baghdad
Nursing Student
Effectiveness of Lemon Essential Oil of Aromatherapy in Reducing Test Anxiety in Nursing Students
This study examines the effectiveness of lemon essential oil in reducing test anxiety in first-year nursing students.
- Trial name
- NCT04426799
- Testing
- lemon essential oil
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis.
This is a Phase III, randomized, one-center, parallel group, double blinded, clinical study to evaluate the efficacy of an alcohol-free mouthwash containing CPC+Zn as compared to dental flossing and to rising with an essential…
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases, Gingivitis and Periodontal Diseases
- Trial name
- PGMWII (NCT06598072)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
Acne
Pilot Study to Evaluate Tea Tree Oil Gel for Facial Acne
Mild to moderate facial acne is an extremely common disease of teenagers and young adults. This pilot study will investigate whether treatment with a gel containing tea tree oil reduces numbers of acne lesions and improves acne…
- Trial name
- NCT01657110
- Testing
- Tea tree oil
- Where
- 2 sites in Australia
- Volunteers
- 18 people
- Sponsor
- The University of Western Australia
High Blood Pressure
Sticker Pad Containing Essential Oil in Volunteer With High Blood Pressure
The aims of the study were to evaluate efficacy and safety of the sticker pads containing lavender and ylang ylang oil in high blood pressure volunteers
- Trial name
- NCT05808556
- Testing
- Sticker pads containing lavender and ylang ylang oil
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Chulalongkorn University
Scalp Health, Hair Condition
Scalp Care Efficacy Evaluation for Premium Scalp Revitalizing Essence
The study aims to evaluate the efficacy of the Premium Scalp Revitalizing Essence on human scalp skin. A total of 60 healthy adults, aged 18 to 60, will be recruited and randomly assigned into five groups receiving different…
- Conditions
- Scalp Health, Hair Condition, Hair Loss, Sebum Production
- Trial name
- NCT06985121
- Testing
- Base formula only, Base formula plus IGF-1 and FGF-7, Base formula plus Centella asiatica extracellular vesicles
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Multiple Sclerosis (MS), Neurogenic Bladder Disorder
Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients
The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population.
- Conditions
- Multiple Sclerosis (MS), Neurogenic Bladder Disorder, Urinary Incontinence (UI), Urinary Urgency
- Trial name
- AROMA-MS (NCT07599189)
- Testing
- Essential Oil Blend (Lavender, Rosemary), Neutral Carrier Oil (Apricot Kernel Oil)
- Where
- 2 sites in Algeria
- Volunteers
- 60 people
- Sponsor
- University of Oran 1
Postoperative Pain
Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）
This national, multi-center, randomized controlled study, through the study of intravenous injection of estaketamine in elderly patients undergoing surgery, is expected to explore whether estaketamine can improve the acute…
- Trial name
- NCT07063108
- Testing
- Esketamine hydrochloride, Saline
- Volunteers
- 276 people
- Sponsor
- Chinese PLA General Hospital
Osteoarthritis
Efficacy and Safety of Topical Essential Oil Extracted From Zingiber Cassumunar Rokb in Osteoarthritis
The objectives of this study are to assess short term efficacy and safety of of topical preparation of essential oil extracted from ZINGIBER CASSUMUNAR ROXB in patients suffering from osteoarthritic pain
- Trial name
- NCT01794260
- Testing
- Cream from Zingiber cassumunar Roxb. extract
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Bronchiolitis
Efficacy of Lavender Essential Oil Chest Wraps in Infants With Bronchiolitis
The goal of this clinical trial is to learn if lavender essential oil chest wraps relieve cough in infants with bronchiolitis compared to standard care.
- Trial name
- NCT06108648
- Testing
- Lavender essential oil 10%, diluted in 90% olive oil, Control
- Where
- 2 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
Epidermolysis Bullosa
ESSENCE Study: Efficacy and Safety of SD-101 Cream in Participants With Epidermolysis Bullosa
The aim was to assess the efficacy and safety of SD-101-6.0 cream versus Placebo (SD-101-0.0) cream in the treatment of skin lesions in participants with Epidermolysis Bullosa.
- Trial name
- NCT02384460
- Testing
- SD-101-6.0 cream
- Where
- 38 sites in United States, Australia and 11 more
- Volunteers
- 169 people
- Sponsor
- Scioderm, Inc.
Gingivitis
A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen
The study will determine the effects of adding mechanical plaque control to a person's oral care regimen. Participants who qualify to participate in the study will will have an equal chance of being assigned to one of three…
- Trial name
- NCT01419626
- Testing
- Interdental cleaning device with water, Interdental cleaning device with essential-oil mouthrinse
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
COVID-19 Respiratory Infection, COVID-19
Efficacy and Safety Study of Essential Oil-Based Preparation Administered to COVID-19 Patients
The aim of this study was to compare the efficacy and safety of the essential oil-based product in patients with mild to moderate symptomatic COVID-19 Positive infection confirmed by PCR.
- Trial name
- NCT06452069
- Testing
- IMMUNO19
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Biodex S.A
Dry Eye Disease
ESSENCE 2: CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)
The objective of this pivotal trial is to assess the efficacy, safety and tolerability of CyclASol in comparison to the vehicle for the treatment of signs and symptoms of Dry Eye Disease (DED).
- Trial name
- NCT04523129
- Testing
- CyclASol topical ocular, eye drops, Vehicle topical ocular, eye drops
- Where
- 27 sites in United States
- Volunteers
- 834 people
- Sponsor
- Novaliq GmbH
Inhalants Craving
Efficacy of Inhalation of Essential Oil on the Reduction of Inhalants Craving
Inhalants, which are neurotoxic central nervous system (CNS) suppressants, are frequently abused by young adults. Unlike other CNS depressants, including alcohol and opiates, no treatment is currently approved for inhalants…
- Trial name
- NCT03296943
- Testing
- Essential oil, Perfume, Cue-induced inhalants craving
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Chulalongkorn University
Healthy
Efficacy and Safety of an Essential Oil-Based Product System for Immune Support
This randomized, double-blind, placebo-controlled clinical trial will evaluate the safety and efficacy of an essential oil-based product system for immune support in healthy adolescents and adults aged 18-45 years.
- Trial name
- OGS (NCT07482644)
- Testing
- Essential Oil Blend (Botanical Combination Product)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Plaque, Gingivitis
Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study
The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and…
- Conditions
- Plaque, Gingivitis, Gum Inflammation, Bleeding
- Trial name
- NCT02980497
- Testing
- Listerine Zero Mouthwash (without alcohol), Listerine Antiseptic Mouthwash (with alcohol)
- Where
- Brazil
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Healthy
Essential Oil-Based Product System for Digestive Support
This study aims to evaluate the efficacy of specific essential oils. Efficacy will be evaluated through changes, if any, to hsCRP, gene expression, and standard hematologic and metabolic parameters, as well as subjective health…
- Trial name
- NCT07653815
- Testing
- essential oil supplement, Essential Oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Gingivitis, Periodontitis
Efficacy of Essential Oil Mouthwash With and Without Alcohol: a 3-Day Plaque Accumulation Model
The daily removal of supragingival dental plaque is a major factor in the prevention of caries, gingivitis and periodontitis. Proper control of bacterial plaque is obtained through the mechanical removal of the biofilm by the…
- Trial name
- NCT01411618
- Testing
- free alcohol essential oil mouthwash
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila