Clinical trials: Effect of Exercise on Cognitive Function
Cognitive Impairment, Cognitive Flexibility
The Effects of Single Exercise Sessions on Cognitive Flexibility and Brain Functional Connectivity in Older Adults With Cognitive Impairment
Objectives: To investigate the effects of different forms (physical and mental, aerobic and resistance) of single exercise on the cognitive flexibility and brain functional connectivity of elderly individuals with cognitive…
- Trial name
- NCT07623954
- Testing
- EXERCISE TRAINING, health education materials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai University of Sport
Aged, Exercise
Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness.
- Conditions
- Aged, Exercise, Cognition, Artificial Intelligence (AI)
- Trial name
- NCT07596082
- Testing
- Artificial intelligence-supported chatbot
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Energy Balance, Physical Activity Level
Effects of Breaking Sitting on Human Behaviour and Metabolic Health
This study primarily aimed to investigate effects of breaking up prolonged sitting with intermittent brisk walking in healthy young individuals on (1) post-trial human behaviours including energy intake and physical activity…
- Conditions
- Energy Balance, Physical Activity Level, Cognition, Metabolic Health
- Trial name
- NCT05911490
- Testing
- Prolonged sitting, Breaking prolonged sitting
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Irisin, Lactate
Effects of Different Types of Exercise on Irisin and Cognitive Performance (Exercise-Irisin)
Purpose The purpose of this study was to determine the acute effects of different exercise intensities on Irisin levels, trail making test performance, and feeling scale.
- Conditions
- Irisin, Lactate, Cognitive Function, Exercise Training
- Trial name
- Ex-Irisin (NCT07146490)
- Testing
- Low Exercise, Long Interval Exercise, Short Intevral Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Cognitive Decline
Modulation Effects of Baduanjin Exercise on Subjective Cognitive Decline
The aim of this study is to investigate the modulation effects of Baduanjin (BDJ), a simple and innovative mind-body exercise, on cognitive function, resting state functional connectivity, and brain morphometry in individuals…
- Trial name
- BDJ (NCT04009382)
- Testing
- Baduanjin Exercise, Cognitive Fitness Program
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Aphasia, Acquired, Aphasia
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
- Trial name
- NCT06185023
- Testing
- Low-intensity physical exercise, High-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, Berkeley
Parkinson Disease, Virtual Reality Therapy
Virtual Reality for Parkinson's Disease
Parkinson's Disease (PD) is one of the most common neurodegenerative disease. Bradykinesia, tremor, resting tremor and postural instability are the main motor characteristics of this disease.
- Conditions
- Parkinson Disease, Virtual Reality Therapy, Functional Magnetic Resonance Imaging
- Trial name
- NCT03637023
- Testing
- Virtual Reality, Exercise Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Farzin Hajebrahimi, PT, MSc
Aphasia, Acquired
Effect of Participation in Virtual Exercise Sessions in Persons With Aphasia
The purpose of this study is to test the feasibility and acceptability of an online exercise program for community-dwelling individuals with aphasia, a language disorder resulting from brain damage.
- Trial name
- NCT05455463
- Testing
- Online aphasia-adapted physical activity class
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- California State University, East Bay
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Breast Cancer, Breast Cancer Survivor
Effects of Supervised Aerobic Exercise on Biomarkers, Physical Function, and Quality of Life in Breast Cancer Survivors
This study evaluates the effects of a 12-week supervised aerobic exercise program in women who have completed primary treatment for early-stage breast cancer and are in remission.
- Conditions
- Breast Cancer, Breast Cancer Survivor, Aerobic Exercise
- Trial name
- NCT07798492
- Testing
- Supervised Aerobic Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Cognitive Ability, General, Brain Health
Investigating the Combined Effects of Intermittent Hypoxia and Exercise on Cognitive and Cerebral Function in Middle-Aged Adults
This study investigates whether intermittent hypoxia (IH) and physical activity (PA), either alone or in combination (simultaneously or sequentially), can improve cognitive function and brain health in middle-aged adults (50-65…
- Conditions
- Cognitive Ability, General, Brain Health, Cerebral Oxygenation
- Trial name
- HYPOX-AGE (NCT06874387)
- Testing
- Hypoxia, intermittent, physical exercise
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ayoub Boulares
Hypertension,Essential, Exercise Activity
Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure
The number of persons with hypertension is increasing and with it the number of related cardiovascular events and related functional or cognitive declines.
- Trial name
- DIISCCO (NCT04103411)
- Testing
- 24h-Ambulatory Blood Pressure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anil Nigam
High Intensity Interval Training, Overweight and Obesity
The HIIT Cognition Study
This pilot study is a randomized control trial to test the effects of a 14-week home-based virtual, interactive high intensity interval training (HIIT) exercise intervention on cardiometabolic and cognitive outcomes in sedentary…
- Conditions
- High Intensity Interval Training, Overweight and Obesity, Metabolic Disease, Cognition
- Trial name
- NCT05137990
- Testing
- HIIT Exercise Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sedentary Behavior, Light Intensity Physical Activity
The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively.
- Trial name
- NCT04716582
- Testing
- Sitting interrupted by light physical activity, Sitting with cognitive task, uninterrupted sitting
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Frailty, Mild Cognitive Impairment
Effects of Square-stepping Exercise on Frailty and Cognitive Function in Elderly With Frailty and MCI
This is a single-blinded, randomized controlled trail with pre- and post-measurements. The inclusion criteria are: (1) age between 65 to 90 years old, (2) the presence of at least one of the 5 physical characteristics defined by…
- Trial name
- NCT04463797
- Testing
- Square-stepping exercise, Stretching and strengthening
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- National Yang Ming Chiao Tung University
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Alzheimer's Disease
Genes, Exercise, Memory and Neurodegeneration
The primary purpose of this pilot study is to determine whether African Americans with mild Alzheimer's disease (AD) can be enrolled and retained in a 6-month aerobic exercise-training study.
- Trial name
- NCT01021644
- Testing
- aerobic exercise-training, stretch exercise
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- Howard University
Low Back Pain, Chronic
Comparative Effects of Group Based Exercises with and Without Cognitive Functional Therapy on Clinical Outcomes in Patients with Chronic Low Back Pain
1.1Research objective The objective of the study is to find the comparative effects of group based exercises with and without cognitive functional therapy on clinical outcomes in patients with chronic low back? 1.2 Hypothesis…
- Trial name
- NCT06759675
- Testing
- group based exercise with Cognitive functional therapy, Group based exercise
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Multiple Sclerosis
Structured Exercise Training in Newly Diagnosed Multiple Sclerosis
the effectiveness of structured exercise training will be investigated for individuals with MS who are newly diagnosed and have no clinical problems.
- Trial name
- NCT05957809
- Testing
- Structured exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Executive Function
The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314634
- Testing
- concurrent exercise, aerobic exercise
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University