Clinical trials: ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, open to volunteers
Mediastinal Lymphadenopathy
Comparison of Two Needle Agitation Strategies in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) for Diagnostic Yield
The goal of this clinical trial is to learn whether the number of needle agitations during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) affects diagnostic yield in patients with enlarged…
- Trial name
- NCT07424807
- Testing
- Needle Agitation Strategy During EBUS-TBNA
- Where
- Vietnam
- Volunteers
- 180 people
- Sponsor
- Phan Quang Hieu
Sarcoidosis Lung, Pulmonary Sarcoidosis
Comparative Diagnostic Yield of Endobronchial Cryo Biopsy vs Forceps Biopsy in Patients With Suspected Sarcoidosis
Sarcoidosis is a multi-systemic granulomatous disease of unknown cause that is characterized by the formation of non-caseous epithelioid cell granulomas.
- Trial name
- CREBS (NCT06853834)
- Testing
- Cryobiopsy with liquid nitrogen, Endobronchial Forceps Biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Suspected Sarcoidosis
Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis
This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared…
- Trial name
- NCT06220526
- Testing
- endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University Health Network, Toronto
Lung Cancer (Diagnosis)
Discrimination of N2a and N2b by EBUS-TBNA: is a Change of the Needle Necessary?
During EBUS staging in patients with mediastinal lymphadenopathy, it is planned to perform a first round of staging with change of the needle between all lymph nodes and a second round of staging without change of the needle.
- Trial name
- NCT07418450
- Testing
- EBUS-TBNA
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- University of Vienna
Non Small Cell Lung Cancer, Non Small Cell Lung Cancer (NSCLC)
Liquid Biopsy Assay of EBUS-TBNA Supernatant Fluid for Diagnosing Lung Cancer
Background and aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the gold standard of lung cancer staging, yet up to 15% of procedures produce inadequate samples for definite diagnosis or…
- Conditions
- Non Small Cell Lung Cancer, Non Small Cell Lung Cancer (NSCLC), Lung Cancer (NSCLC), Lung Cancer - Non Small Cell
- Trial name
- NCT06889467
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Barzilai Medical Center
Mediastinal and Hilar Lymphadenopathy
Diagnostic Value and Safety of Endobronchial Ultrasound-guided Transbronchial Mediastinal Cryobiopsy Versus Transbronchial Needle Aspiration in the Diagnosis of Lymphoma: a Randomized Controlled Trial
The goal of this clinical trial is to learn which of two minimally invasive procedures is better at safely diagnosing lymphoma in the mediastinum (chest) in adults (aged 18 and older) who are suspected to have either a new or a…
- Trial name
- NCT07352267
- Testing
- Endobronchial ultrasound-guided transbronchial needle aspiration, Endobronchial ultrasound-guided tranbronchial mediastinal cryobiopsy
- Volunteers
- 470 people
- Sponsor
- China-Japan Friendship Hospital
Artificial Intelligence, Endobronchial Ultrasound
Augmented Endobronchial Ultrasound (EBUS-TBNA) With Artificial Intelligence
To evaluate the usefulness of Deep neural network (DNN) in the evaluation of mediastinal and hilar lymph nodes with Endobronchial ultrasound (EBUS).
- Conditions
- Artificial Intelligence, Endobronchial Ultrasound, Lung Cancer
- Trial name
- NCT05739331
- Testing
- machine learning algorithm
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Hypoxemia
The Role of Ultrasonographic Tracheal Measurements in Predicting Hypoxemia During Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Bronchoscopic procedures performed under endobronchial ultrasound (EBUS) guidance are widely used minimally invasive diagnostic methods for the evaluation of mediastinal lymph nodes.
- Conditions
- ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Hypoxemia, Trachea
- Trial name
- NCT07587736
- Testing
- TRACHEAL DIAMETER MEASUREMENT, Hypoxemia
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Lung Cancer
Genotyping of Ebus-tbna Supernant Cell-free Dna in Nsclc
The wide uptake of "liquid biopsy" diagnostics in the care of advanced cancer patients highlights the desire for improved access to tumor allowing accurate tumor genotyping (1).
- Trial name
- CELTICS (NCT04624373)
- Testing
- Molecular analysis of surnatant
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Lung Cancer
EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing
This is a multi-center clinical trial evaluating the effect of transbronchial mediastinal cryobiopsy for its ability to improve the likelihood of obtaining tissue sufficient for molecular analysis.
- Trial name
- FROSTBITE-3 (NCT06105801)
- Testing
- Endobronchial ultrasound with transbronchial needle aspiration, Bronchoscopy, Cryobiopsy
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Procedural Sedation and Analgesia
Consent Understanding and Propofol Requirement During Endobronchial Ultrasound
The goal of this observational study is to learn whether a participant's understanding of the informed consent information is related to the amount of propofol needed during endobronchial ultrasound (EBUS).
- Conditions
- ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Procedural Sedation and Analgesia, Informed Consent
- Trial name
- NCT07677982
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Uludag University
Mediastinal Lymphadenopathies
Diagnostic Yield and Safety of Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Comparison of the Diagnostic Yield and Safety Between Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration and Endobronchial Ultrasound-Guided Transbronchial Mediastinal…
- Trial name
- COLLEBERATIONⅢ (NCT07040670)
- Testing
- Confocal laser endomicroscopy-assisted endobronchial ultrasound-guided transbronchial needle aspiration, Endobronchial ultrsound-guided Mediastinal cryobiopsy
- Volunteers
- 469 people
- Sponsor
- China-Japan Friendship Hospital
Lung Cancer
Feasibility of Evaluating Gene Alteration Analysis Using Samples Obtained by EBUS-TBNA in Patients With Lung Cancer
Lung cancer is the leading cause of death in the world. Overall 5-year survival rate is fewer than 10% and the effectiveness of conventional chemotherapy is limited.
- Trial name
- NCT01487603
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
Lung Neoplasms, Bronchoscopy
Feasibility and Preliminary Performance of an AI Prototype for Digital ROSE During EBUS-TBNA and Peripheral TBNA: a Prospective Pilot Study (AI-ROSE-FEAS)
Rapid On-Site Evaluation (ROSE) of cytological slides obtained during EBUS-TBNA improves diagnostic yield by providing real-time adequacy assessment and preliminary diagnostic orientation after each needle pass.
- Conditions
- Lung Neoplasms, Bronchoscopy, AI (Artificial Intelligence), Mediastinal ( Chest) Masses
- Trial name
- AI-ROSE-FEAS (NCT07662967)
- Testing
- ROSE
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliera di Rilievo Nazionale A.Cardarelli
Mediastinal Metastases of Lung Cancer
Diagnostic Value and Safety of Combined Biopsy for Mediastinal Metastasis of Lung Cancer
The study is aimed o evaluate the diagnostic performance and treatment guidance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with transbronchial mediastinal cryobiopsy (EBUS-TBMCB) in…
- Trial name
- NCT07488507
- Testing
- EBUS-TBMCB
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Third Military Medical University
Lung Cancer
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiotherapy (SBRT)
It is reported that more than 90,000 patients died of lung cancer and more than 20% of them were older than 80 years in North America.
- Trial name
- NCT01786590
- Testing
- EBUS-TBNA
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University Health Network, Toronto
Lymphadenopathy
EBUS-TTFB vs EBUS-TBNA for Diagnosing Inadequate Lymph Node Specimens Based on MOSE
The study aims to compare the efficacy and safety of endobronchial ultrasound-guided transtunnel forceps biopsy to transbronchial needle aspiration in diagnosing inadequate lymph node specimens based on macroscopic on-site…
- Trial name
- NCT06913569
- Testing
- EBUS-TBNA, EBUS-TTFB
- Where
- 3 sites in China
- Volunteers
- 162 people
- Sponsor
- Shanghai Chest Hospital