Clinical trials: Dying Process
Terminal Illness
iLIVE Volunteer Study
The aim of this study is to develop and evaluate the implementation of an international volunteer training programme to support patients dying in the hospital setting and their families. It has the following objectives: 1.
- Trial name
- NCT04678310
- Testing
- Support from the hospital palliative and end of life care volunteer service (developed for this study).
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Liverpool
Terminal Cancer
Nasal Fentanyl and Buccal Midazolam for Dying Patients
When patients are dying they become unable to take oral medication and if they develop symptoms (e.g. pain or agitation) they need to be given a subcutaneous injection of medication.
- Trial name
- NCT02009306
- Testing
- PecFent and Epistatus, Standard subcutaneous medication, Epistatus Alone
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Organ Donation After Circulatory Death
Brain-based Prediction of the Dying Duration in Humans After Withdrawal of Life Sustaining Therapies to Inform Donation After Circulatory Death
The purpose of this study is to develop a new tool that uses information collected before life-sustaining treatments are withdrawn to better predict whether a patient will die within the time needed for organ donation to be…
- Trial name
- NeuroDCD (NCT07698262)
- Where
- 11 sites in Canada
- Volunteers
- 102 people
- Sponsor
- University of British Columbia
Critical Illness
Intensive Care Decision-making, Survival and Dying Well
The goal of this study is to investigate how the experiences of intensive care patients and their end-of-life wishes affect their willingness to accept intensive care treatment at different chances of survival.
- Trial name
- NCT06027684
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Manchester
Palliative Care
Study to Improve Care for Veterans During Serious Illness
Improving end-of-life care is of critical importance to the VA as it faces an increasingly aging and dying veteran population. Previous work within and outside of the VA has demonstrated serious deficiencies in the quality of…
- Trial name
- NCT00106041
- Testing
- Veterans Integrated Palliative Care Nurse Case Manager
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
Pain Intractable, Delirium
Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients
Cancer patients with very difficult to control symptoms at the Abbotsford (AC) and Fraser Valley (FVC) Cancer Centers are referred and admitted to the Tertiary Palliative Care Units at the Abbotsford Regional Hospital and Cancer…
- Conditions
- Pain Intractable, Delirium, Dyspnea, Nausea
- Trial name
- NCT01687751
- Testing
- Dexmedetomidine, Midazolam
- Where
- Canada
- Sponsor
- Fraser Health
Terminal Diseases, Terminal Care
Medical Assistance in Dying Requests in Pain Clinic
Terminally ill patients often suffer existentially. Terminally ill patients with existential pain may request medical aid in dying.
- Conditions
- Terminal Diseases, Terminal Care, Chronic Pain, Disability or Chronic Disease Leading to Disablement
- Trial name
- MAiD (NCT06802562)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Salem Anaesthesia Pain Clinic
Cancer, Depression
Spirituality, Religiosity, and Immune Functioning
The purpose of this study is to determine whether religiosity and spirituality are related to immune functioning, as measured by interleukin-6 blood plasma level, among terminally ill cancer patients.
- Conditions
- Cancer, Depression, Dying Process
- Trial name
- NCT00066924
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Family of Dying Patient in the ICU
A Communication Strategy for Families of Patients Dying in the ICU
Decisions to limit life sustaining treatments are made for most patients dying in the ICU, usually with input from the family. The well-being of the family may be jeopardized by involvement in the decision-making process and…
- Trial name
- NCT00331877
- Testing
- family conference with bereavement information leaflet
- Volunteers
- 136 people
- Sponsor
- Famirea Study Group
Illness Terminal
Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy
The Conscious Dying/Conscious Living study will investigate the effect of KAP (ketamine-assisted psychotherapy) on individuals with terminal illness at five separate geographic locations.
- Trial name
- KRF-EOL (NCT05214417)
- Testing
- Ketamine Injectable Solution, Naturalistic Control
- Volunteers
- 120 people
- Sponsor
- The Ketamine Research Foundation
Suicide, Assisted, Fasting
Self-directed Dying in the Netherlands
In 2007, the frequency of so-called 'self-directed dying' in the Netherlands was investigated, that is, the voluntary cessation of eating and drinking or the taking of lethal self-collected medication.
- Conditions
- Suicide, Assisted, Fasting, Decision Making
- Trial name
- NCT06186791
- Where
- Netherlands
- Volunteers
- 37,500 people
- Sponsor
- Erasmus Medical Center
End of Life Care, Violent Aggressive Behavior
Death, Dying, Violence and Aggression as Shown on Medical Television Series.
Medical TV dramas have become very popular in recent years. These shows are mainly created for entertainment and often do not reflect what really happens in hospitals.
- Conditions
- End of Life Care, Violent Aggressive Behavior, Television Viewing, Media Use
- Trial name
- NCT07416669
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College Hospital NHS Trust
Cancer
Evaluation of Multidisciplinary Palliative Care on Terminal Cancer Patients in Taiwan
The purpose of the study is to compare the quality of dying and death of terminal cancer patients from the perspectives of medical staff and main care giver (family). The hypothesis is that their view points will be different.
- Trial name
- NCT01103700
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
End-of-Life
Improving Quality of Care for the Dying Patient in Hospice: A Quasi Experimental Trial in Liguria Region
This is a before-after phase II study, according to the Medical Research Council framework, investigating the feasibility of introducing the Liverpool Care Pathway for the dying patient (LCP) in 5 Ligurian hospices.
- Trial name
- NCT01470625
- Testing
- LCP Program
- Where
- 5 sites in Italy
- Volunteers
- 282 people
- Sponsor
- Regional Palliative Care Network
Physician-Assisted Suicide
Physician-assisted Dying in Mentally Ill Patients - Which Criteria Are Decisive?
Physician-assisted dying (PAD) is currently a highly controversial topic in medical ethics and public debates worldwide. It poses a moral conflict between the ethical principle of respect for patient autonomy and the ethical…
- Trial name
- NCT05492461
- Volunteers
- 20,000 people
- Sponsor
- Psychiatric Hospital of the University of Basel
Cessation of Life
Research Into the Quality of the Dying Phase
The aim of this study is to get insight in the quality of life at the end of life and quality of dying for patients died at the hospital in the department Groningen (the Netherlands).
- Trial name
- NCT02822690
- Testing
- Hospice care at UMCG
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- University Medical Center Groningen
Incurable Cancer Diseases, Other Incurable Diseases
Incurable Ill Patients Attitudes Towards Euthanasia and Assisted Suicide
Euthanasia and assisted dying are of growing interest for patients with incurable diseases. The possible methods are widely discussed by patient-societies, physicians, lawyers, theologians and philosophers.
- Trial name
- ESPIL (NCT00495482)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Klinikum St. Georg gGmbH
Assisted Dying, Palliative Care
Palliative Care and The Terminally Ill Adults (End of Life) Bill
The current study aims to investigate the potential impact of the proposed Assisted Dying (Terminally Ill Adults (2024) Bill on Palliative care workers.
- Trial name
- NCT07427550
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Neoplasms, Bereavement
ERANet-LAC CODE: International Care Of the Dying Evaluation
Providing high quality care for dying patients and their families is very important. One way one can assess the care provided is to ask bereaved relatives to complete a questionnaire after their family member has died.
- Conditions
- Neoplasms, Bereavement, Quality of Life
- Trial name
- NCT03566732
- Where
- 20 sites in Argentina, Brazil and 5 more
- Volunteers
- 914 people
- Sponsor
- University of Bergen