Clinical trials: Drying Time
Dry Eye Disease
Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops
The goal of this research is to evaluate and compare the effectiveness of Systane® versus Optive™ on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the possible application for this…
- Trial name
- NCT00610480
- Testing
- 1st visit Optive, then 2nd visit Systane, 1st visit Systane, then 2nd visit Optive
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Keratoconjunctivitis Sicca
Effect of Controlled Adverse Environment (CAE) on Tear Film Stability
The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.
- Trial name
- NCT01547936
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ORA, Inc.
Blast Overpressure Exposure, Blast Injuries
Biomarkers of Brain Health in Blast Overpressure Exposure
The purpose of this study is to learn whether headsets that measure brainwaves can find early signs of changes in brain health in tactical operators who train near explosive blasts.
- Conditions
- Blast Overpressure Exposure, Blast Injuries, Brain Health, Occupational Exposure
- Trial name
- NCT07783048
- Testing
- Blast overpressure exposure during explosive breaching training
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Neurable, Inc
Dry Eye Syndrome
Residence Time Evaluation of Systane Ultra Lubricant Eye Drops vs. Hialid and Saline
The purpose of this study is to evaluate the ocular retention time of Systane Ultra compared to Hialid and saline.
- Trial name
- NCT01252121
- Testing
- Systane Ultra Lubricant Eye Drops, Hialid 0.1 Artificial Tears Eye Drops, Unisol 4 Saline Solution
- Volunteers
- 27 people
- Sponsor
- Alcon Research
Dry Eye
Efficacy and Safety Study of FID 119515A
The purpose of this study was to compare the effect of FID 119515A to Blink® Tears on the integrity of tear film in adults with a history of dry eye in both eyes.
- Trial name
- NCT01833117
- Testing
- FID 119515A, Blink® Tears
- Volunteers
- 75 people
- Sponsor
- Alcon Research
Dry Eye
Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects
The purpose of this study is to demonstrate the superior efficacy of Systane® Balance over Preservative-Free 0.9% Saline following 35 days of QID (4 times a day) dosing in treating dry eye subjects with lipid deficiency.
- Trial name
- NCT01967147
- Testing
- Propylene Glycol, 0.6% eye drops, Preservative-free 0.9% Saline solution
- Volunteers
- 279 people
- Sponsor
- Alcon Research
Dry Eye Syndrome
Correlation of Different Signs for Assessment of Dry Eye Syndrome
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response of the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01753687
- Testing
- Ocular scattering of the tear film, Optical Coherence Tomography (OCT), Measurement of tear film osmolarity
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Dry Eye
Tear Osmolarity Changes After Instilling Isotonic Hyaluronate Artificial Tears
Background: Osmolarity is defined as the concentration of particles dissolved in a solution. Normal tears contain various dissolved particles including proteins, salts and other electrolytes.
- Trial name
- NCT01614847
- Testing
- Artificial tears
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Thomas O Salmon, OD, PhD
Dry Eye Syndrome (DES), Ocular Surface Disease
Twice-Daily Systane Complete Versus Four-Times-Daily Thealoz Duo for Dry Eye Disease
The goal of this clinical trial is to learn whether a twice-daily dosing schedule of Systane Complete eye drops works as well as a four-times-daily dosing schedule of Thealoz Duo eye drops to treat dry eye disease in adults.
- Trial name
- NCT07722650
- Testing
- Systane Complete, Thealoz Duo
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Instituto Internacional de Medicina y Terapia (IIMET)
Asthma
A Comparison of Critical Errors, Overall Errors, Training/Teaching Time, and Preference Attributes of the ELLIPTA Versus BREEZHALER Dry Powder Inhalers (DPIs) in Adult Participants With Asthma
This study aims to provide data in adult participants with mild to moderate asthma to assist healthcare professionals (HCPs) in assessing various attributes of ELLIPTA and BREEZHALER DPIs, by comparing the incidence of critical…
- Trial name
- NCT04813354
- Testing
- ELLIPTA, BREEZHALER
- Where
- 3 sites in Netherlands
- Volunteers
- 114 people
- Sponsor
- GlaxoSmithKline
Dry Eye Syndrome (DES), Hand Osteoarthritis
Ocular Surface Disease Index and Dry Eye Parameters in Hand Osteoarthritis
This study investigates whether the relationship between the Ocular Surface Disease Index (OSDI) and dry eye parameters can be used as a predictive marker in patients diagnosed with hand osteoarthritis.
- Trial name
- NCT07789054
- Testing
- Dry Eye and Ocular Surface Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Medipol University
Dry Eye Disease
Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time
The purpose of the study is to observe lacrimal fluid condition (tear film break-up time) chronologically after a single dose of AL-43546 ophthalmic products（0.15%, 0.25% and vehicle）and 0.1% sodium hyaluronate ophthalmic…
- Trial name
- NCT00760045
- Testing
- Hydroxypropyl Guar Galactomannan, 0.1% sodium hyaluronate ophthalmic solution
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Mitochondrial Degradation, Autophagy
Mitophagy and Mitochondrial DNA Dynamics During Ramadan Dry Fasting vs 16:8 Time-Restricted Feeding
This study investigates how different types of fasting affect cell health, specifically focusing on how mitochondria (the energy-producing parts of cells) are cleared and renewed.
- Conditions
- Mitochondrial Degradation, Autophagy, Fasting, Healthy Volunteers
- Trial name
- MITO FAST (NCT07638696)
- Testing
- Ramadan Intermittent Dry Fasting (Sawm), 16:8 Time-Restricted Feeding (TRF)
- Where
- Cyprus
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bahcesehir Cyprus University
Dry Eye
A Study of ALTY-0501 for the Treatment of Dry Eye Administered 4 Times a Day for a 56 Day Period
The objective of this study is to assess the safety and efficacy of doxycycline 0.025% (ALTY-0501) ophthalmic solution for the treatment of dry eye using the Controlled Adverse Environment (CAE) Model.
- Trial name
- NCT00439400
- Testing
- doxycycline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Alacrity Biosciences, Inc.
Sports Physical Therapy
Effects of Explosive Plyometric Training Versus Thera-Band Power Training on Sprint Swimming Performance
This randomized controlled trial will compare the effects of upper-limb explosive plyometric training and TheraBand-based power training on sprint swimming performance in competitive swimmers.
- Trial name
- NCT07791693
- Testing
- Closed-Chain Explosive Plyometric Training, Open-Chain TheraBand-Based Power Training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University