Clinical trials: Dry Skin
Cataract
Analysis of Cataract Surgery Induced Dry Eye
This is a retrospective study to determine if rates of osmolarity and dry eye disease symptoms increase following cataract surgery.
- Trial name
- NCT01471561
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- TearLab Corporation
Xerostomia
Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms
This will be a single center, 7-day, examiner blind, two treatment-arm, randomized, stratified (Sjogren's Syndrome status [Y/N]), parallel group study conducted in participants experiencing dry mouth symptoms.
- Trial name
- NCT02641912
- Testing
- Biotene mouthwash, Mineral Water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Evaporative Dry Eye
Impact of Tear Substitute Use on Dry Eye in Gamers.
Clinical, prospective, comparative, controlled, single-blind study, on the signs and symptoms of dry eye before and after 3 days of playing video games with the use of artificial tears (Hyabak) versus no intervention.
- Trial name
- HYAGAME (NCT05536661)
- Testing
- Preservative free hyaluronic acid artificial tear
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Laboratorios Thea, Spain
Pulmonary Disease, Chronic Obstructive
A Phase I Pharmacokinetic Study of Fluticasone Furoate /Umeclidinium Bromide/Vilanterol (100/62.5/25 Microgram [mcg]) After Single and Repeat Dose Administration From a Dry Powder Inhaler in Healthy Chinese Subjects
This is an open-label study to evaluate the PK of FF/UMEC/VI in dose combinations of 100/62.5/25 mcg after single and repeat dose administration from a DPI in healthy Chinese subjects.
- Trial name
- NCT02837380
- Testing
- FF, VI/UMEC
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dry Eye Syndrome
Phase I Study to Evaluate the Tolerability of Eye Drop DA-6034 in Healthy Volunteers
This is a double-blind, randomized, placebo-controlled, 4-period, cross-over clinical trial. The study is designed to evaluate the safety and local tolerability of DA-6034 upon single and repeated-dose topical application to the…
- Trial name
- NCT01162954
- Testing
- DA-6034
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Skin Inflammation, Cosmetic Skin
35 kDa Hyaluronan Fragment (HA35) Reduces Chronic Inflammation of Skin
To explore the clinical effect and safety of 35 kDa hyaluronic acid fragment ( HA35 ) combined with negative pressure microneedle technology in improving skin problems.
- Trial name
- NCT06387212
- Testing
- 35 kDa hyaluronan fragment HA35 injection
- Where
- Mongolia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nakhia Impex LLC
Dry Eye Syndromes, Lubricant Allergy
Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects
Phase I clinical study, to evaluate the safety and tolerability of the preservative-free ophthalmic solution PRO-087 versus Xyel Ofteno® and Systane Ultra®, on the ocular surface of ophthalmological and clinically healthy…
- Conditions
- Dry Eye Syndromes, Lubricant Allergy, Tear Disorder
- Trial name
- PRO-087/I (NCT03524157)
- Testing
- PRO-087, Systane Ultra, Xyel Ofteno
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Skin Abnormalities
Moisturizing Effect of Two Dexpanthenol Formulations
The study focuses to prove the equivalent moisturizing effect of two different Dexpanthenol formulations
- Trial name
- NCT00839280
- Testing
- Dexpanthenol foam spray, new formulation, Dexpanthenol foam spray, old formulation
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bayer
Dry Skin, Skin Care
To Evaluate the Effect of Moisturizing Creams on Skin Barrier Function
The aim of this study is to evaluate the impact of twice-daily topical application of two different moisturizing creams on skin barrier function for 4 weeks.
- Trial name
- NCT03804710
- Testing
- Developmental moisturizing cream 1, Developmental moisturizing cream 2, Standard cleanser soap
- Where
- Germany
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Comparing Two Respiratory Drugs in Combination and Separately From a Novel Inhaler Device in Healthy Japanese Subjects
A combination of the corticosteroid GW685698X and the long-acting ß2-agonist GW642444M is being developed for once daily administration for the maintenance treatment of asthma and COPD.
- Trial name
- NCT00625196
- Testing
- Fluticasone foroate/ vilanterol, Fluticasone foroate, Vilanterol
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Dry Eye Syndromes
Altaire Gel Forming Solution Versus Refresh Tears for the Treatment of Dry Eye Signs and Symptoms
The purpose of this study is to evaluate and compare the effects of Altaire Gel forming solution and Refresh Tears in mild-moderate dry eye patients.
- Trial name
- NCT01382810
- Testing
- Altaire Gel forming solution, Refresh Tears
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Dry Mouth
Bioequivalency Study of 5 mg Pilocarpine Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Pilocarpine Tablets, 5 mg, to SALAGEN® Tablets, 5 mg (MGI Pharma) under fasting conditions using a single-dose, 2-treatment, 2-period, crossover design.
- Trial name
- NCT00601874
- Testing
- Pilocarpine
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Dry Skin, Sensitive Skin
Evaluation of Hydrating Cream Effect on Subjects With Dry Skin.
The goal of this clinical trial is to learn if a cosmetic product works to improve skin condition in adults with dry, very dry, sensitive and cracked skin showing discomfort.
- Conditions
- Dry Skin, Sensitive Skin, Cracked Skin
- Trial name
- NCT07393191
- Testing
- Repairing cream
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Dry Eye Syndromes
Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime Gel
Objective: To assess the safety and tolerability of the PRO-165 formulation on the ocular surface of ophthalmologically and clinically healthy subjects.
- Trial name
- PRO-165 (NCT03697876)
- Testing
- PRO-165, Artelac
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye Syndrome
Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery
This study will evaluate the safety and efficacy of a new artificial tear for the treatment of dry eye that may occur after LASIK surgery
- Trial name
- NCT00544713
- Testing
- Carboxymethylcellulose and Glycerin based artificial tear, Carboxymethylcellulose
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Allergan
Rheumatoid Arthritis, Systemic Lupus Erythematosus
A Trial in Healthy Adult Participants and Adults With Autoimmune Diseases to Test How HBM7020 is Tolerated and How it Behaves in the Body
This first-in-human study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of HBM7020.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, Sjögren's Disease
- Trial name
- NCT07649265
- Testing
- HBM7020
- Where
- Australia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Participants
A Phase 1 Study of Navlimetostat Tablet Formulations
This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female
- Trial name
- NCT07544628
- Testing
- Navlimetostat
- Where
- 4 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Dry Age-related Macular Degeneration
Observational Study of Vision Improvement in Late Stage Dry AMD Patients
The purpose of this study is to assess the vision improvement achieved by patients with late stage dry age-related macular degeneration who received corneal treatments by a low vision aid device.
- Trial name
- NCT04349254
- Testing
- Corneal treatment by a low vision aid device
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Optimal Acuity Corporation
Skin Dryness
Glyceryl Eicosapentaenoate Based Topic Products as an Irritant-free Cream and Serum for Hydration of Sensitive Skin
This exploratory study aims to verify the hydrating potential as well as the possible irritant effects of a 14-day hydrating treatment consisting of daily application of serum and cream to the skin of two dry targeted areas.
- Trial name
- COS-PBP-01 (NCT06219213)
- Testing
- Glyceryl Eicosapentaenoate serum, Glyceryl Eicosapentaenoate Cream A, Glyceryl Eicosapentaenoate Cream B
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- SCF Pharma