Clinical trials: Drug Monitoring
Healthy Participants
A Sub Study to Evaluate the Study Medication (Etrasimod) Using Wearable Sensors in Healthy Participants
The purpose of this study is to look at how healthy adults process Etrasimod when assessed by wearable sensors. Etrasimod is taken without food and assessments taken by site staff and then by participants after training.
- Trial name
- NCT06140290
- Testing
- Etrasimod Immediate Release (IR)
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pfizer
Fertility Disorders
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
In-vitro fertilisation (IVF) treatment involves women undergoing hormone stimulation (drug dosing) to produce more oocytes (eggs) to increase their chances of fertilisation.
- Trial name
- NCT05634850
- Testing
- Kinder
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Planet Innovation
Chemotherapy, Nerve Degeneration
Serial Electrophysiologic Monitoring During Administration of Nerve-Toxic Chemotherapeutic Drugs
The study hypothesis is that changes in serially obtained nerve conduction study data obtained every 3-4 weeks in cancer patients receiving chemotherapy can be used to predict the development of a clinically significant /…
- Conditions
- Chemotherapy, Nerve Degeneration, Nerve Conduction
- Trial name
- NCT01208545
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NeuroMetrix, Inc.
Opioid Related Disorders, Opiate Addiction
Monitoring Patterns of Prescribing to Identify Changes in Access to ER/LA Opioid Analgesics
Changes in prescribing will be compared in prescribers from specialties whose prescribing is hypothesized to be relatively unaffected by the REMS (such as oncologists and hospice providers) versus those for whom the REMS could…
- Conditions
- Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02920775
- Testing
- Non-interventional study - retrospective database review
- Volunteers
- 360,000 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Epilepsy
Birth Defects Associated With Exposure to Lamotrigine in Pregnancy (EUROCAT)
In 2007 a case control study was completed within the EUROCAT European network of congenital anomaly registers to test the hypothesis that first trimester lamotrigine monotherapy exposure is associated with an increased risk of…
- Trial name
- NCT01055327
- Testing
- Lamotrigine monotherapy, No anti-epileptic drug exposure, Non lamotrigine anti-epileptic drug monotherapy
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Respiratory Disease
A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device
This goal of this study is to assess the suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) device for patients on injectable medications in the home-setting, for the…
- Trial name
- NCT05592769
- Testing
- HealthBeacon Injection Care Management System (ICMS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HealthBeacon Plc
Mental Disorders
Enhanced Medication Reconciliation For Serious Mental Illness
The purpose of this study is to evaluate the clinical utility of a decision support tool, the Patient Medication Profile(TM), developed by Sano Informed Prescribing on medication reconciliation and identification of drug-related…
- Trial name
- NCT03169868
- Testing
- Sano Patient Medication Profile
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Precera Bioscience, Inc.
Clinical Deterioration, Hemodynamic Instability
Early Identification of Clinical Deterioration Using a Wearable Monitoring Device
This study aims to provide myriad of physiological parameters in patients admitted in an internal medicine department, and which are defined as being in an increased risk of clinical deterioration within the first 72-hours after…
- Trial name
- NCT04220359
- Testing
- non-invasive monitoring
- Where
- Israel
- Volunteers
- 410 people
- Sponsor
- Biobeat Technologies Ltd.
Medication Adherence, Hypertension
An Enhanced Medication Monitoring Program
The goal of the Enhanced Medication Management Program (eMMp) being developed by MedMinder Systems, Inc. is to increase the ability of frail elders to adhere to complex medication regimens for chronic conditions.
- Trial name
- NCT01105104
- Testing
- MedMinder System, MedMinder System - deactivated
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- MedMinder Systems Inc.
Palonosetron
Intensive Medicines Monitoring Project of Palonosetron Hydrochloride Capsules (Ruo Shan®)
Observe palonosetron hydrochloride capsules'(Ruo Shan®) safety and efficacy information in the real world using.
- Trial name
- NCT03148704
- Testing
- palonosetron hydrochloride capsules
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Cttq
Cancer
Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only
The goal of this clinical trial is to learn if Resilience PRO, a digital solution performing remote symptoms monitoring, can improve the quality of life of patients with a diagnosis of cancer receiving systemic anticancer…
- Trial name
- RC-102 (NCT06867705)
- Testing
- Resilience PRO
- Where
- 36 sites in France, Germany
- Volunteers
- 1,458 people
- Sponsor
- Resilience
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Hypertension
Precision Nudging for Hypertension Management: Observational Study
The purpose of the proposed observational study is to explore the relations between data-driven personalization and equitable health outcomes in a digital health intervention (DHI) for hypertension management.
- Trial name
- NCT06354192
- Testing
- Precision Nudging for Hypertension Management
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Lirio
Drug Abuse
A First Study in Healthy Volunteers of a New Mobile Phone Application Measuring the Eyes Before and After Medication
This is a pre-market, explorative, early feasibility, pilot, controlled clinical investigation designed to collect initial clinical data on the medical device Previct Drugs.
- Trial name
- NCT05731999
- Testing
- Previct Drugs
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kontigo Care AB
Traumatic Brain Injury
Crainio Non-invasive ICP Monitor for TBI
The clinical investigation aims to advance the Crainio device, designed for non-invasive intracranial pressure (ICP) monitoring.
- Trial name
- NCT06453733
- Testing
- Crainio
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Crainio Ltda
Hyperthyroidism, Graves Disease
AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' Disease
Graves' disease is the most common cause of hyperthyroidism and is usually treated with antithyroid drugs such as methimazole (MMI).
- Conditions
- Hyperthyroidism, Graves Disease, Thyrotoxicosis
- Trial name
- NCT07857421
- Testing
- Glandy HYPER (AI-based monitoring software), Methimazole
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- THYROSCOPE INC.
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Analgesics - Surveillance Monitoring of State Medical Examiner Databases
In April 2011, the U.S. Food and Drug Administration (FDA) determined that a class-wide risk evaluation and mitigation strategy (REMS) for all extended-release (ER) and long-acting (LA) opioid medications was necessary to support…
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02897414
- Testing
- Surveillance of state medical examiner databases
- Volunteers
- 13,015 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
High Blood Pressure
Blood Pressure Treatment by the Corsano CardioWatch 287-2 Evaluation Study
Rationale: Wearables have the potential to monitor patients remotely. The Corsano CardioWatch 287-2 is such a medical device that can monitor long-term blood pressure.
- Trial name
- BPTreat (NCT06508619)
- Testing
- Corsano CardioWatch 287-2 non-invasive blood pressure (NIBP) monitoring
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Corsano Health B.V.
Intraoperative Ureter Injury
Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery
Phase 2, multicenter, efficacy and safety study evaluating the use of nerindocianine for the delineation of abdominopelvic ureter anatomy via near infrared fluorescence imaging during minimally invasive lower abdominal surgery…
- Trial name
- NCT04636567
- Testing
- Nerindocianine for injection
- Where
- 2 sites in United States
- Sponsor
- Li-Cor, Inc.
Blood Pressure, Blood Pressure Variability
This Study Aims to Assess the Performances of Optical Blood Pressure Monitoring Device, tBPC Product With Reference to ISO 81060-3:2022
In this study, according to the latest released ISO 81060-3:2022 standard requirements, non-invasive blood pressure measurement by cuff at the start and the end time points will be used as oCareTM BP100 start-to-end blood…
- Trial name
- NCT06815614
- Testing
- A Photoplethysmography-Based Continuous Automated Non-Invasive Sphygmomanometer
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taiwan Biophotonic Corporation