Clinical trials: Drug Addiction
Cocaine Related Disorders
Stress and Medication Effects on Cocaine Cue Reactivity
Stressful situations and cues associated with cocaine can lead to craving in cocaine dependent individuals. The purpose of this study is to determine whether guanfacine or modafinil are effective in reducing stress and cue…
- Trial name
- NCT00613015
- Testing
- Guanfacine, Modafinil
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Medical University of South Carolina
Mental Disorders, Drug Addiction
Treatment of Hepatitis C in Psychiatric Patients
Psychiatric disorders or drug addiction are often regarded as contraindications against the use of Interferon-alpha in patients with chronic hepatitis C.
- Trial name
- NCT00751426
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Charite University, Berlin, Germany
Hepatitis C, Medication Adherence
Patient-Centered Models of HCV Care for People Who Inject Drugs
People who inject drugs (PWID) have higher rates of hepatitis C virus (HCV) than do other groups. Effective, safe new treatments called direct-acting antiviral agents (DAAs) have been developed recently.
- Trial name
- HERO (NCT02824640)
- Testing
- Patient Navigation, modified Directly Observed Therapy
- Where
- United States
- Volunteers
- 755 people
- Sponsor
- Prisma Health-Upstate
Opioid Medication Assisted Treatment
Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment
Opioid use disorder (OUD) is a major cause of illness and death among Veterans for which effective treatment is a major priority of the Veterans Health Administration (VHA).
- Trial name
- CONDUIT (NCT04178551)
- Testing
- Implementation Facilitation
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Drug Craving Levels Among Individuals With Substance Addiction, Depression Levels Among Individuals With Substance Addiction
The Effects of Exercise and Music Combination on Drug Cravings, Depression and Self-Efficacy Among Drug Addicts
This study focuses on the rehabilitation of drug addicts by combining exercise and music, to find out whether exercise and exercise combined with music of different rhythms will have an improvement for drug addicts. 1.
- Conditions
- Drug Craving Levels Among Individuals With Substance Addiction, Depression Levels Among Individuals With Substance Addiction, Self-efficacy Among Individuals With Substance Addiction
- Trial name
- NCT07279246
- Testing
- Sports group, Exercise combined with fast-paced music group, Exercise combined with slow-tempo music group
- Where
- Malaysia
- Volunteers
- 92 people
- Sponsor
- WEIPENG DUAN
Drug Use, Alcohol Use
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
This study will assess Specialized Community Disease Management (SCDM), an intervention which employs various evidence-based strategies to engage substance using co-morbid patients while in the hospital and follow them into the…
- Conditions
- Drug Use, Alcohol Use, Congestive Heart Failure, Pneumonia
- Trial name
- NCT02059005
- Testing
- Specialized Community Disease Management, Treatment As Usual
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Treatment Research Institute
Cocaine Dependence
D-Serine for Cocaine Dependence Pilot
The primary objective of this study is to collect pilot data on the efficacy of D-serine, relative to placebo, as a cocaine dependence treatment. Secondary objectives include evaluating D-serine, relative to placebo, on: 1.
- Trial name
- STED-CD (NCT01715051)
- Testing
- D-serine, Cognitive Behavioral Therapy
- Where
- United States
- Sponsor
- Theresa Winhusen
Heroin Dependence, Opioid-Related Disorders
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2
The purpose of this study is to compare the clinical efficacy of daily vs. 3-day (MWF) buprenorphine/naloxone combination tablet administration and determine whether outcomes are improved when using a 3-day schedule in which all…
- Trial name
- NCT00000327
- Testing
- Heroin Dependence
- Where
- United States
- Sponsor
- University of Colorado, Denver
Substance Abuse, Substance Dependence
Group Therapy for Women Prisoners With Comorbid Substance Use and Depression
The purpose of the study is to determine whether interpersonal psychotherapy is effective for treating co-occurring depression and substance use among women prisoners.
- Conditions
- Substance Abuse, Substance Dependence, Depressive Disorder
- Trial name
- NCT00606996
- Testing
- Group interpersonal psychotherapy (IPT-G), Psychoeducation on co-occurring disorders (PSYCHOED)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brown University
HIV Infections, Substance Use Disorders
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV testing and linkage to HIV prevention and treatment services in…
- Conditions
- HIV Infections, Substance Use Disorders, Addiction, Opioid Use
- Trial name
- NCT06103370
- Testing
- Peer-educator-based network
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Alcohol Dependence
CRF1 Antagonist GSK561679 in Alcoholism
Objective: To evaluate GSK561679, an orally available, brain penetrant selective CRH1 antagonist for its ability to reduce alcohol craving in recently detoxified alcohol dependent women in response to stress or alcohol-associated…
- Trial name
- NCT01187511
- Testing
- GSK561679
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Substance-Related Disorders
Transcranial Direct Current Stimulation on Inhibitory Control in Addictions.
The research in neuroscience of the last 20 years is defined, in addition to continuing to advance in the field of behavioral and pharmacological therapy, by the birth and development of a new therapeutic category, called…
- Trial name
- NCT05350033
- Testing
- tDCS - tDCS
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad de Almeria
Analgesic Drug Dependence, Sensory Deficit
Quantitative Sensory Testing in Chronic Pain Patients Undergoing Opioid Treatment and Opioid Tapering
Few studies have used quantitative sensory tests to study the effect of chronic opioid treatment on sensation. The investigators will test chronic pain patients who are on different MEDDs, normal volunteers, and patients…
- Trial name
- NCT03375216
- Testing
- sensory testing (Heat, cold, and pressure), Promis Survey
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Digital Technology, Technology Addiction
The Effect of Health Education Based Laughter Yoga Applied to Adolescents on Stress and Digital Gaming Habits
Adolescents may turn to digital games as a coping mechanism for stress, which can lead to addiction and various health problems.
- Conditions
- Digital Technology, Technology Addiction, Internet Addiction Disorder, Laughter Yoga
- Trial name
- Digital Habits (NCT07032090)
- Testing
- Health education, Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Alcohol; Liver
Integrating Care for Patients With Alcohol Liver Disease and Alcohol Use Disorders
Alcohol related liver disease (ALD) contributes to 50% cases of cirrhosis worldwide and is the leading indication for liver transplant in North America.
- Trial name
- NCT05375682
- Testing
- Integrated care program
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
HIV Infections, AIDS
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Background: The incidence of lung cancer is quite high among people with the human immunodeficiency (HIV) virus. Frequent smoking may explain that cancer increase, given that 50% to 70% of HIV-infected people are current smokers.
- Conditions
- HIV Infections, AIDS, Lung Cancer, Tobacco Addiction
- Trial name
- NCT00491335
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Methamphetamine Dependence
Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
Modafinil is a non-amphetamine type stimulant that acts as a wakefulness-promoting drug, and is approved for managing symptoms of narcolepsy (i.e., daytime somnolence).
- Trial name
- Modafinil (NCT00469508)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles