Clinical trials: Dissociative Seizures
Epilepsy, Dissociative Seizures
Stress and Seizures - Can a Brief Self-help Book Help?
Background: Epilepsy and nonepileptic attack disorder (NEAD) are chronic conditions that cause many patients to experience a great degree of stress in their everyday lives.
- Trial name
- NCT02465047
- Testing
- Self-help booklet
- Where
- United Kingdom
- Volunteers
- 82 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Psychogenic Nonepileptic Seizures, Psilocybin
Evaluation of the Effect of a Single Dose of Psilocybin on Neural Correlates of Cognitive Control in Patients With Psychogenic Nonepileptic Seizures
Psychogenic non-epileptic seizures (PNES) are functional paroxysmal motor disorders that may be clinically suggestive of epilepsy but are not associated with the electroencephysiological and electroencephalographic changes of…
- Trial name
- CRIPSY (NCT06647056)
- Testing
- Psilocybin, MRI
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Non Epileptic Seizures, Functional Neurological Symptom Disorder
Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures
The objective of this study is to determine the effects of the ketogenic diet on the frequency of non-epileptic seizures in patients with functional neurological symptoms disorder compared to a healthy diet.
- Conditions
- Non Epileptic Seizures, Functional Neurological Symptom Disorder, Conversion Disorder, Ketogenic Dieting
- Trial name
- NCT05219006
- Testing
- ketogenic dieting, healthy dieting
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Convulsion, Nonepileptic, Conversion Disorder
Comparing Different Treatments in Reducing Dissociative Seizure Occurrence
The study will test the hypothesis that Cognitive Behavioural Therapy plus Standardised Medical Care (SMC) will have greater clinical and cost effectiveness than SMC alone in treating adult patients with dissociative seizures…
- Conditions
- Convulsion, Nonepileptic, Conversion Disorder, Dissociative Disorder
- Trial name
- CODES (NCT02325544)
- Testing
- Cognitive Behavioral Therapy, Standardized Medical Care
- Where
- 40 sites in United Kingdom
- Volunteers
- 368 people
- Sponsor
- King's College London
Convulsion, Non-Epileptic, Conversion Disorder
Treatment Trial for Psychogenic Nonepileptic Seizures
The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline)…
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NEST-T_1 (NCT00835627)
- Testing
- sertraline, CBT-ip, Combined (sertraline + CBT-ip)
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Epilepsy, Dissociative Seizures
Mainz Epilepsy Registry
Prospective longitudinal observational registry study of all patients with epilepsy treated in the Mainz Comprehensive Epilepsy and Sleep Medicine Center with the focus on the course of the disease and quality of life.
- Conditions
- Epilepsy, Dissociative Seizures, Status Epilepticus
- Trial name
- MAINZ-EPIREG (NCT05267405)
- Testing
- no interventions, only observation
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- Johannes Gutenberg University Mainz
Convulsion, Non-Epileptic, Conversion Disorder
Treatments for Psychogenic Nonepileptic Seizures (NES)
The investigators propose that treatment of the comorbid disorders (depression, anxiety, and impulsivity) with sertraline in patients with lone psychogenic nonepileptic seizures (NES), will result in a decreased number of NES.
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NES (NCT00159965)
- Testing
- sertraline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Psychogenic Nonepileptic Seizures, Dissociative Seizures
ADIE-FS - Aligning Dimensions of Interoceptive Experience in Patients With Functional Seizures
Functional seizures are common and harmful. They look like epileptic seizures but are not caused by the excess electrical discharges in the brain that arise in epilepsy.
- Conditions
- Psychogenic Nonepileptic Seizures, Dissociative Seizures, Psychogenic Pseudoseizure, Functional Neurological Disorder
- Trial name
- ADIE-FS (NCT06105996)
- Testing
- Interoceptive training
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Functional Neurological Disorder, Dissociative Seizures
The Feasibility and Acceptability of an Online Yoga Program for People With Functional Neurological Disorders
This is a feasibility study to see if it is acceptable and helpful for people living with a functional neurological disorder to receive online group yoga sessions to improve their wellbeing
- Conditions
- Functional Neurological Disorder, Dissociative Seizures, Psychogenic Seizure, Non-Epileptic Seizure
- Trial name
- YOGA-FUND (NCT07077603)
- Testing
- A12 week, twice weekly, small group, online yoga program
- Volunteers
- 30 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Psychogenic Non Epileptic Seizure
Evaluation of a Telephone Follow-up Procedure on the Quality of Life in Psychogenic Non-epileptic Seizures
The goal of this study is to evaluate effectiveness of the phone follow-up method compared to the conventional filler taken one.
- Trial name
- EDUQ-CPNE (NCT02311829)
- Testing
- Telephone follow-up device
- Where
- 4 sites in France
- Volunteers
- 136 people
- Sponsor
- Central Hospital, Nancy, France
Convulsion, Non-Epileptic
Automated Identification of Psychogenic Nonepileptic Seizures
A retrospective validation study of a post-processing method intended to identify psychogenic nonepileptic seizures
- Trial name
- NCT03013348
- Testing
- Brain Sentinel's sEMG Post-processing algorithm
- Volunteers
- 104 people
- Sponsor
- Brain Sentinel
Psychogenic Non-Epileptic Seizure, Depression
Project UPLIFT for Psychogenic Non-Epileptic Seizures
Developed by researchers from the Centers for Disease Control and Prevention (CDC), Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts) is a group telephone program designed to improve depression for…
- Conditions
- Psychogenic Non-Epileptic Seizure, Depression, Non-Epileptic Seizure, Psychogenic Seizure
- Trial name
- PNES (NCT03329703)
- Testing
- Project UPLIFT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Psychogenic Non-epileptic Seizures
Emotional Lived in Patients Suffering From Psychogenic Nonepileptic Seizures : Study by Functional Magnetic Resonance Imaging
Currently, hypothetical models of understanding Psychogenic Non-epileptic Seizures (PNES) involve emotional dysregulation. The hypothesis of a disorder of emotional experience is mainly based on behavioral data and disturbance of…
- Trial name
- EMOCRISES (NCT02976545)
- Testing
- fMRI (functional Magnetic Resonance Imaging), psychiatric evaluation
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Psychogenic Non-Epileptic Seizure
TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder
The aim of the study is to compare the effect of Transcranial Magnetic Stimulation (TMS) versus treatment with selective serotonin reuptake inhibitors (SSRIs), in patients with diagnosis of Functional Neurological Non Epileptic…
- Trial name
- NCT05241366
- Testing
- Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Psychogenic Nonepileptic Seizures (PNESs)
Quality of Life and Psychogenic Nonepileptic Seizures.
The goal of this study is to identify the prognostic factors of quality of life in patients with psychogenic non-epileptic seizures
- Trial name
- PronoCNEP (NCT02821208)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Dissociative Seizures, Functional Seizures
Assessing the Impact of Brief CBTi on Dissociative Seizures: SCED
Some people experience a temporary change in behaviour and consciousness, that often involves a collapse and/or shaking limb movements. These are referred to as 'Dissociative seizures'.
- Conditions
- Dissociative Seizures, Functional Seizures, Psychogenic Nonepileptic Seizures, Insomnia
- Trial name
- CBTi 4 DS:SCED (NCT06145971)
- Testing
- brief Cognitive Behavioural Therapy for Insomnia (bCBTi)
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Glasgow
Somatoform Disorders, Irritable Bowel Syndrome
Neurovegetative Decoupling in Somatoform Disorders : Biofeedback Interest
Evaluation of the physiological and clinical effects of the biofeedback training with patients suffering from somatoform disorders, depending on their neurovegetative profile related to a visceral-brain decoupling.
- Conditions
- Somatoform Disorders, Irritable Bowel Syndrome, Psychogenic Non-Epileptic Seizure
- Trial name
- BIOFEESOMATO (NCT04807933)
- Testing
- Heart rate variability Biofeedback [HRV-BFB]
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Functional Seizures, Convulsion, Non-Epileptic
A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures
The purpose of this study is to assess the feasibility of conducting a future fully powered multi-site efficacy Randomized Controlled Trial (RCT) comparing two treatments for pediatric functional seizures (FS).
- Trial name
- NCT05819268
- Testing
- ReACT, CATCH-IT
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Psychogenic Seizure, Epilepsy, Temporal Lobe
Self-modulation of the Sense of Agency by Means of Real-time Neurofeedback
This study investigates whether the sense of agency is sensitive to self-regulation by means of EEG-based neurofeedback. During neurofeedback, the brain activity in response to a motor task is recorded in real-time and displayed…
- Conditions
- Psychogenic Seizure, Epilepsy, Temporal Lobe, Health, Subjective
- Trial name
- NF-Agency (NCT05214833)
- Testing
- Real Neurofeedback
- Where
- Switzerland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Psychogenic Nonepileptic Seizures (PNES)
Cognitive Rehabilitation for Veterans With PNES
Psychogenic nonepileptic seizures (PNES) reflect a subtype of functional neurological disorder (FND) that is common and extremely disabling in Veterans.
- Trial name
- CRVWP (NCT07316543)
- Testing
- Cognitive Rehabilitation And Functional Treatment (CRAFT)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development