Clinical trials: Disk Herniated Lumbar
Disk, Herniated
Safety and Effectiveness Study of the AO-1000 Device to Treat Contained Herniated Discs
To evaluate the safety and effectiveness of the AO-1000 device to treat and relieve the pain of symptomatic subjects with contained herniated discs. This single-arm pilot study will be used as a go vs.
- Trial name
- NCT01339377
- Testing
- AO-1000
- Where
- 3 sites in Canada
- Volunteers
- 39 people
- Sponsor
- ActiveO Inc.
Degenerative Disc Disease, Spondylolisthesis
Retest-reliability and At-home-assessment Feasibility of the 5R-STS
The five-repetition sit-to-stand test has been validated and is used primarily in pulmonary medicine and cardiology, and has recently been shown to be a useful tool for the objective assessment of functional impairment in…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- 5RSTS-2 (NCT03321357)
- Testing
- five-repetition sit-to-stand test
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Bergman Clinics
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anesthesia, Disk Herniated Lumbar
Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery
The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.
- Conditions
- Anesthesia, Disk Herniated Lumbar, Intraocular Pressure
- Trial name
- NCT06070480
- Testing
- Spinal Anesthesia Group, Desflurane Group, Propofol Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Inflammation, Neutrophil
SIII and Spontaneous Regression in Lumbar Disc Herniation
This study aimed to investigate the role of the Systemic Immune-Inflammatory Index (SIII) in patients with lumbar disc herniation (LDH) and to evaluate its potential clinical relevance in relation to treatment modality.
- Conditions
- Inflammation, Neutrophil, Lymphocyte, Neurosurgery
- Trial name
- SIII-LDH (NCT07367503)
- Testing
- Lumbar disc herniation treatment, Lumbar disc herniation surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Lumbar Disc Herniation, Annular Tear of Lumbar Disc
Post-Marketing Clinical Follow-Up of a Spine Implant
Post-Marketing Clinical Follow-up of an Anular Closure System (Barricaid®) to Confirm Comparability of Outcome between Devices with Subcomponents from Two Different Suppliers
- Trial name
- PMCFU (NCT03180749)
- Testing
- Follow up per standard of care
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Intrinsic Therapeutics
Lumbar Disc Herniation
Telerehabilitation Program in Lumbar Disc Herniation
The aim of this study was to develop an asynchronous, web-based telerehabilitation exercise and monitoring program and to compare its effectiveness with a traditional brochure-based home exercise program in patients with lumbar…
- Trial name
- NCT07501910
- Testing
- Web-Based Telerehabilitation Exercise Program, Brochure-Based Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Disc Herniations, Disc Herniation, Lumbar
Smartwatch Accuracy for Measuring Vitals and Anxiety Before Disc Surgery
This study aims to verify the accuracy of blood pressure, heart rate, blood oxygen saturation, anxiety level, and sleep cycle data measurements obtained from Samsung smartwatches compared to the currently accepted method used in…
- Conditions
- Disc Herniations, Disc Herniation, Lumbar, Cervical Disc Herniation, Preoperative Anxiety Score
- Trial name
- NCT07322523
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Halil Kalaycı
Lumbar Disc Herniation, Lumbar Disc Degeneration
The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease
The goal of this study is to clarify the role of the bacterium Cutibacterium acnes in the development of degenerative disc disease in patients with lumbar disc herniation who underwent microdiscectomy as part of their regular…
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Degeneration, Cutibacterium Acnes, Low Back Pain
- Trial name
- NCT07085247
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Masaryk University
Disk Hernisi, Visseral Manuel Terapi
The Effect of Visceral Osteopathic Manual Therapy in Lumbar Disc Herniation
This study aims to investigate the impact of adding visceral osteopathic manual therapy techniques to conservative physical therapy on the lives of individuals with lumbar disc herniation.
- Trial name
- NCT07465068
- Testing
- osteopathic manual therapy, FTR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Rumeli University
Lumbar Disc Herniation
Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
This study compares an endoscopic transforaminal surgical technique for the treatment of a herniated disc to the standard microsurgical procedure. Clinical parameters as well as health economy will be assessed.
- Trial name
- TESCORT (NCT01622413)
- Testing
- joimax TESSYS, Microdiscectomy
- Where
- 3 sites in Austria, Germany
- Sponsor
- Joimax GmbH
Lumbar Disc Herniation
Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.
- Trial name
- NCT04049812
- Testing
- PEMF, Hot pack, TENS
- Volunteers
- 50 people
- Sponsor
- Birkan Sonel Tur
Disc Herniation
Fear-Avoidance Beliefs and Physical Function in Patients With Lumbar Disc Herniation
Lumbar disc herniation is one of the most common causes of low back pain and is associated with substantial functional limitations and reduced quality of life, particularly among working-age individuals.
- Trial name
- FAB-LDH (NCT07674407)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Istinye University
Lumbar Disc Herniation, Radiculopathy Lumbar
The Effect of Ultrasound Guidance on Radiation Dose and Procedure Time in Lumbar Transforaminal Epidural Injection
Low back pain is one of the leading causes of disability, and its social burden and economic cost are quite high. Although there are many causes that can lead to low back pain, radicular pain, which develops mostly secondary to…
- Trial name
- NCT05793528
- Testing
- Fluoroscopy Guided Transforaminal Epidural Steroid Injection, Ultrasound Guided Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
LUMBAR RADICULOPATHY, Lumbar Radiculopathy Due to Spinal Nerve Compression
Maitland Mobilization Effect On Gait Kinetics And Kinematics Parameters In Patients With Lumbosacral Radiculopathy
Effect Of Maitland Mobilization On Selected Gait Kinetic And Kinematic Parameters In Patients With Lumbosacral Radiculopathy
- Conditions
- LUMBAR RADICULOPATHY, Lumbar Radiculopathy Due to Spinal Nerve Compression, Lumbar Disc Prolapse With Radiculopathy, Lumbosacral Radiculopathy
- Trial name
- NCT07448311
- Testing
- MAITHLEND MOBILIZATION, transcutaneous electrical neuromuscular stimulation, stretching hamstrings
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Nurses, Comfort
The Effect of Kegel Pelvic Floor Muscle Exercises on Urinary Retention, Pain, and Comfort Levels in Patients After Lumbar Disc Herniation Surgery: A Randomized Controlled Clinical Trial
This study was planned as a randomized controlled trial to investigate the effects of Kegel pelvic floor muscle exercises on urinary retention and comfort levels of patients after lumbar disc herniation surgery.
- Conditions
- Nurses, Comfort, Surgery
- Trial name
- NCT06578221
- Testing
- Kegel Pelvic Floor Muscle Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Lumbar Disc Herniation
Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
Low back and leg pain caused by lumbar disc herniation (LDH) is common. Lever positioning manipulation (LPM) is a spinal manual therapy used to relieve this pain, but how it affects the brain is unclear.
- Trial name
- NCT07728149
- Testing
- Active Lever Positioning Manipulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic LDH
Restoration of Sensorimotor Function in Middle-Aged Women With Chronic Lumbar Disc Herniation: The Effect of Pilates on Proprioception, Tibialis Anterior Strength, and Dynamic Balance
The aim of this study is to determine the effects of core stabilization-focused Pilates exercises on sensorimotor function in middle-aged women diagnosed with chronic lumbar disc herniation (LDH).
- Trial name
- Chronic LDH (NCT07515287)
- Testing
- Pilates Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University