Clinical trials: Diseases of the Temporomandibular Joint, active
Temporomandibular Disorders (TMD)
Feasibility and Acceptability of OLP-EXP in Chronic Pain
The primary objective is to determine the feasibility of delivering OLP-EXP, EXP only, and OLP only over 6 weeks to adults with chronic TMD.
- Trial name
- NCT07735520
- Testing
- OLP-EXP, OLP, EXP
- Volunteers
- 57 people
- Sponsor
- University of Maryland, Baltimore
TMJ, Apical Periodontitis
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional…
- Conditions
- TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth
- Trial name
- NCT05439330
- Testing
- MRI of teeth and surrounding structures
- Where
- Denmark
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders
Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System
The goal of this clinical trial is to investigate the possible role of levonorgestrel intrauterine system use(LIU) in the pathogenesis of temporomandibular joint disorder (TMD).
- Conditions
- Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders, Temporomandibular Disorder
- Trial name
- NCT06500390
- Testing
- Examination of temporomandibular joint and masticator muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management
The aim of the study is to evaluate the effectiveness of intra-articular platelet-rich fibrin (iPRF) injections in the management of moderate and mild cases of degeneration of the temporomandibular joints.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Arthritis, Temporomandibular Joint Osteoarthritis
- Trial name
- NCT05214924
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorders (TMD), Orofacial Pain
Comparing the Effectiveness of Online vs. Face-to-face Physiotherapy for Treating Temporomandibular Disorders
Dentists and physiotherapists have two options for treating these conditions: splint therapy and physiotherapy. Right now, the gold standard is individual physiotherapy, which contains manual therapy and active exercises too.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Temporo-mandibular Dysfunction, Temporomandibular Joint and Muscle Disorder
- Trial name
- NCT07474662
- Testing
- Individual physiotherapy, Group physiotherapy, Online physiotherapy
- Where
- 2 sites in Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University
Temporomandibular Disorder
The New Serial Treatment of Temporomandibular Disorders
The purpose of this study is to look at temporomandibular joint (TMJ) pressure as a guideline to analyze the different treatments for temporomandibular disorder (TMD), and judge the feasibility of the adjust TMJ pressure…
- Trial name
- NCT00932594
- Testing
- Adjust the TMJ Pressure to Normal Value, Do not adjust the pressure of TMJ
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Sun Yat-sen University
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD), Manual Therapy
Effectiveness of the Fascial Distortion Model in Temporomandibular Disorders: A Randomized Sham-controlled Trial
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control.
- Conditions
- Temporomandibular Disorders (TMD), Manual Therapy, Fascial Distortion
- Trial name
- NCT06627855
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Temporomandibular Joint Disorders
Temporomandibular Joints Mobility and Head Posture: Influence of Manual Therapy and Exercises in Dental Patients.
Goal: This clinical study aims to investigate how the range of motion of the temporomandibular joints (TMJ) changes in relation to the patient's head posture.
- Trial name
- NCT07297251
- Testing
- Manual therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain
EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief
This prospective, multi-center, open-label, single-arm clinical study will evaluate the efficacy and performance of the BTL-043 and BTL-785F devices for alleviating TMJ pain.
- Conditions
- Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
- Trial name
- NCT07661121
- Testing
- Treatment with BTL-043 and BTL-785F
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- BTL Industries Ltd.
Temporomandibular Disorder (TMD), Chronic Pain
Patient Education, Self-management and Physiotherapy for Chronic Temporomandibular Disorders
The goal of this clinical trial is to understand whether a simple education and self-management program with home exercises can reduce pain and improve daily function in adults with long-lasting jaw pain caused by…
- Trial name
- NCT07423234
- Testing
- Patient education and self-management, Usual treatment (multimodal)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Text Neck Syndrome, Temporomandibular Joint Disorders
Comparison of Cervical and TMJ Parameters in Young Adults With and Without Text Neck Syndrome
The aim of this cross-sectional study is to compare temporomandibular joint (TMJ) and cervical spine parameters between young university students aged 18-30 years with and without text neck syndrome, a modern overuse condition…
- Conditions
- Text Neck Syndrome, Temporomandibular Joint Disorders, Postural Balance
- Trial name
- NCT07851805
- Volunteers
- 80 people
- Sponsor
- Borna Farhoomand
CLASS II DIVISION 1 MALOCCLUSION
Twin-Block and LIPUS for TMJ Outcomes in Skeletal Class II Patients
Evaluation of the efficacy of early treatment of skeletal class II patients with twin-block in conjunction with low intensity pulsed ultrasound on temporomandibular joint region: a prospective clinical trial
- Trial name
- AlAzharU (NCT07676695)
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ
Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in the Management of Temporomandibular Joint Disorders
Occlusal splint therapy is a well-established conservative approach for the management of temporomandibular disorders (TMDs); however, variability in clinical outcomes suggests that no single splint design is universally optimal.
- Conditions
- Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint, Anterior Disc Displacement
- Trial name
- NCT07760428
- Testing
- Conventional Stabilization Splints, 3d printed Stabilization splint, Novel hybrid stabilization splint
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Temporomandibular Disorders (TMDs)
Hard Splint Vs Conservative Therapy for TMJ Pain Management
The purpose of this study is to compare the efficacy of a hard occlusal splint versus conservative therapy (using topical Ibuprofen gel and counseling) in the management of patients with temporomandibular (TMJ) joint disorders.
- Trial name
- NCT07573137
- Testing
- Hard occlusal splint, Counseling and Habit Modification, Topical Ibuprofen gel
- Volunteers
- 60 people
- Sponsor
- Khyber College of dentistry
Temporomandibular Disorders (TMD)
Occlusal Splint and Exercise Therapy for Temporomandibular Disorders
The goal of this clinical trial is to learn if an exercise protocol can improve temporomandibular pain, jaw function and muscle mechanical properties in individuals with Temporomandibular Disorders (TMD).
- Trial name
- NCT07507734
- Testing
- Occlusal Splint, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Acibadem University
Healthy, Temporomandibular Joint Disorders
ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging
The Real Time MRI Rapid Flash sequence is particularly interesting for the study of moving organs and joints. This sequence will make it possible to characterize normal and pathological temporomandibular joint movements by MRI.
- Trial name
- ARTEMIS (NCT06070558)
- Testing
- MRI with Real Time MRI Rapid Flash sequence
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Temporomandibular Disorder (TMD)
The Effectiveness of Different Therapeutic Jaw Position Determining Methods in Repositioning Splint Therapy for Temporomandibular Joint Disk Displacement Without Reduction：A Randomized Controlled Clinical Trial
The goal of this clinical trial is to learn if different therapeutic jaw position determining methods influence the efficacy of repositioning splint therapy for temporomandibular joint disk displacement without reduction.
- Trial name
- NCT07090772
- Testing
- Repositioning splint therapy with jaw position determined by mechanical articulator, Repositioning splint therapy with jaw position determined by ai-assisted virtual articulator, Repositioning splint therapy with jaw position determined by ai-assisted virtual patient
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Fujian Medical University
Temporomandibular Joint Osteoarthritis
Intra-articular Allocetra in Osteoarthritis of the of the Temporomandibular Joint (TMJ)
This study is a single center trial to assess the safety and initial efficacy of intra-articular administration of Allocetra to patients with Temporomandibular Joint Osteoarthritis (TMJ-OA)
- Trial name
- NCT06748651
- Testing
- Allocetra
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Dr. Amit Druyan