Clinical trials: Discopathy
Lumbar Discopathy, Lumbar Disc Herniation
The Effect of Physiotherapy on Respiratory Function and Psychosocial Status in Lumbar Discopathy
The aim of this study is to investigate the effects of physiotherapy on pulmonary function tests and psychosocial status in patients with lumbar discopathy. Participants undergo a 15-session physiotherapy program.
- Trial name
- NCT07789067
- Testing
- Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Medipol University
Discopathy, Herniated Cervical Disc
Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.
- Conditions
- Discopathy, Herniated Cervical Disc, Stenoses, Spinal, Radiculopathy
- Trial name
- PMCF_MOVE®-C (NCT05035693)
- Testing
- MOVE®-C
- Where
- 7 sites in Austria, Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NGMedical GmbH
C-CURVE , Cervical Interbody Cage, Cervical Disc Disease
Prospective Clinical Study to Evaluate the Efficacy of the Stand-alone Cervical Interbody Cage C-CURVE ( Titanium) Manufactured by MEDICREA®
This study includes one type of product named C-CURVE which is a Stand-alone Cervical Interbody Cage. This product is available in two materials: PEEK and Titanium.
- Conditions
- C-CURVE , Cervical Interbody Cage, Cervical Disc Disease, Cervical Discopathy
- Trial name
- C-CURVE (NCT04547959)
- Testing
- cervical interbody cage C-CURVE
- Where
- 10 sites in Belgium, France
- Volunteers
- 82 people
- Sponsor
- Medicrea International
Cervical Discopathy
Effects of Physiotherapy and Breathing Exercises on Patients With Cervical Discopathy.
This study evaluates whether adding breathing exercises to standard physical therapy helps improve lung function and overall well-being in people with cervical discopathy (neck problems).
- Trial name
- NCT07777770
- Testing
- Conventional Physiotherapy, Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medipol University
Discopathy, Lumbago
Correlation Between RMI of Degenerative Disk Disease and Reduction of Pain After Disk-infiltration Treatments
The primary objective of the study is to demonstrate the difference in the reduction of pain at 1 month after intradiscal infiltration of corticosteroids depending on symmetrical or asymmetrical active discopathies with MRI…
- Trial name
- MODISC (NCT04142580)
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Discopathy, Back Pain
Physiotherapy in Thoracic Discopathy
Background and Objective: Information regarding the effects of physiotherapy on quality of life and alterations in pulmonary function tests among patients with thoracic discopathy is notably limited in the literature.
- Conditions
- Thoracic Discopathy, Back Pain, Respiratory Dysfunction
- Trial name
- NCT07749248
- Testing
- Traditional Physiotherapy, Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Lumbar Degenerative Disease, Lumbar Radiculopathy
Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation
The goal of this clinical trial is to compare the clinical effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in patients aged 18-85 with single-level lumbar disc herniation who have not undergone…
- Conditions
- Lumbar Degenerative Disease, Lumbar Radiculopathy, Sciatic Leg Pain, Sciatic Nerve Compression
- Trial name
- NCT06615518
- Testing
- FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- University of Opole
Intubation Complication, Cervical Discopathy
Comparison of C-Mac D Blade and Fastrach Laryngeal Mask Airway on Cervical Spine Motion Conditions
In patients with cervical spine disorders or hernia, in-line stabilization and immobilization during tracheal intubation is used to avoid neck injury. With direct laryngoscopy cranio-cervical motion can result injury.
- Trial name
- NCT03115606
- Testing
- C-Mac D Blade, Fastrach LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Diskapi Teaching and Research Hospital
Intervertebral Disc Degeneration, Modic I Discopathy
Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease
The purpose of this study is to determine whether pamidronate is effective and well-tolerated in the treatment of painful degenerative disk disease, also known as Modic type 1 changes
- Conditions
- Intervertebral Disc Degeneration, Modic I Discopathy, Back Pain, Low Back Pain
- Trial name
- NCT01799616
- Testing
- Pamidronate
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spine Degeneration, Fusion of Spine (Disease)
Lumbar Discopathy Decompression with Lateral Interbody Fusion: Radiological and Clinical Outcomes
The aim of the study was to introduce a single-segment lumbar spine decompression and fusion with intervertebral implants through modified by the authors lateral lumbar approach.
- Trial name
- NCT06719349
- Where
- Poland
- Volunteers
- 38 people
- Sponsor
- Podkarpackie Oncological Center
Surgical Injury, Back Pain Lower Back Chronic
Spinal Approach for Lumbar Active Discopathy
The study aims to study the impact on different surgical approaches for lumbar active discopathy. This inflammatory disease of the disc and adjacent vertebral endplates can induce low back pain with inflammatory-like features.
- Trial name
- NCT04086199
- Testing
- Lumbar discectomy
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Disorder of Spine
Mazor X Stealth Versus O-arm Navigation for Pedicle Screw Insertion
The investigators would like to investigate the fluoro-registered Mazor X Stealth in terms of pedicle screw accuracy and radiation exposure in comparison with the O-arm and navigation as the institutional gold standard.
- Trial name
- RGNV (NCT04353895)
- Testing
- Guidance for pedicle screw insertion (Mazor Stealth), Guidance for pedicle screw insertion (O-arm Navigation)
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- P. D. Dr. med. Duccio BOSCHERINI
Chronic Low Back Pain
Intra-discal Injection of PRP for Low Back Pain
Low back pain (LBP) is the second cause of medical visits in France. Indeed, its incidence can vary between 60 and 90%. LBP is also the leading cause of disability in the adult population in France and in the rest of the world.
- Trial name
- MODI-PRP (NCT03712527)
- Testing
- Injection of Platelet rich plasma, Injection of NaCl
- Where
- 6 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Montpellier
Cervicobrachial Neuralgia, Cervical Discopathy
GRANVIA®-C Cervical Disc Prosthesis Multicenter European Pilot Study
This is a prospective clinical study to assess the performance of the prosthesis according to a composite success criterion. The clinical and functional results and the patient's quality of life up to 24 months of follow-up will…
- Trial name
- NCT01518582
- Testing
- Cervical arthroplasty surgery with Granvia-C
- Where
- 3 sites in Belgium, France
- Volunteers
- 70 people
- Sponsor
- Medicrea International
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Low Back Pain, Lumbago
Assessment of the Efficacy of an Intradiscal Injection of Corticoids in Modic I Discopathies.
The treatment of chronic low back pain is a major objective of public healthcare, because it causes an important number of sick leaves.
- Conditions
- Low Back Pain, Lumbago, Modic I Discopathy
- Trial name
- MODISC (NCT01694134)
- Testing
- Hydrocortancyl., Lidocaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Disability Evaluation, Recovery of Function
Diagnostic Methods and VR Therapy for Cervical Spine Discopathy
The study will assess modern diagnostic methods and evaluate the rehabilitation effects of virtual reality (VR) therapy in patients with cervical spine discopathy.
- Trial name
- NCT06589557
- Testing
- Virtual Reality (VR) and Standard Rehabilitation, Standard Rehabilitation
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Back Pain Lower Back Chronic
Intra-discal Steroid Injection for MODIC I Discopathy
To assess the efficacy on pain level at 1 month and 12 months of a steroid injection in the inter-vertebral disc for patients with chronic back pain and inflammatory discopathy on magnetic resonance imaging.
- Trial name
- PREDID (NCT00804531)
- Testing
- Visipaque - Hydrocortancyl
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Notalgia Paresthetica
High-power Laser Therapy for Notalgia Paresthetica.
A non-invasive modality for the management of neuromusculoskeletal pain conditions that has emerged as a compelling option is high-power laser therapy (HPLT).
- Trial name
- NCT07356362
- Testing
- High-power laser
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uşak University
Meralgia Paresthetica
The Efficacy of High-Power Laser Therapy in Meralgia Paresthetica
The management of MP typically follows a conservative pathway, encompassing patient education, lifestyle modifications (e.g., avoidance of tight garments, weight loss), pharmacotherapy (such as neuropathic pain agents or…
- Trial name
- NCT07328360
- Testing
- High-power laser, Standard Conservative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uşak University