Clinical trials: Disability Physical
Quadriplegia, Spinal Cord Injury
Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis
This study was intended to evaluate a new assistive neuro-technology, known as the Tongue Drive System (TDS), by its potential end-users, i.e.
- Conditions
- Quadriplegia, Spinal Cord Injury, ALS
- Trial name
- TDS-1 (NCT01124292)
- Testing
- Tongue Piercing, Usability assessment
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Multiple Sclerosis
Study of Teriflunomide in Reducing the Frequency of Relapses and Accumulation of Disability in Patients With Multiple Sclerosis
The primary objective was to determine the effect of teriflunomide on the frequency of relapses in patients with relapsing multiple sclerosis (MS).
- Trial name
- TEMSO (NCT00134563)
- Testing
- Teriflunomide
- Where
- 21 sites in United States, Austria and 19 more
- Volunteers
- 1,088 people
- Sponsor
- Sanofi
Chronic Pain, Brain Injuries, Traumatic
Telehealth Pain Self-Management for Employed Adults
The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with physical disabilities who are employed.
- Conditions
- Chronic Pain, Brain Injuries, Traumatic, Multiple Sclerosis, Spinal Cord Injuries
- Trial name
- E-TIPS (NCT04248725)
- Testing
- E-TIPS
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Washington
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertension, Physical Disability
The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults
This study will examine the effects of low sodium meal plan on seated blood pressure in older adults from a community-based, congregate senior living facility.
- Conditions
- Hypertension, Physical Disability, Aging
- Trial name
- SOTRUE (NCT04074941)
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Anxiety Depression, Disability Physical
Exploratory Study for Toivoa-001 on Human Factors
The Study will evaluate Rauha as an experimental digital therapeutic for persons with Disabilities suffering from anxiety and/or depression.
- Trial name
- NCT06477913
- Testing
- Rauha
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Toivoa Inc
Sedentary Lifestyle, Risk of Disability
The LIFE Study - Lifestyle Interventions and Independence for Elders
Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized…
- Conditions
- Sedentary Lifestyle, Risk of Disability, Aging
- Trial name
- LIFE (NCT01072500)
- Testing
- Physical Activity, Successful Aging
- Where
- 8 sites in United States
- Volunteers
- 1,635 people
- Sponsor
- University of Florida
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Breast Cancer
mHealth Behavioral Cancer Pain Intervention for Medically Underserved Patients
The efficacy of a mobile health (mHealth) behavioral cancer pain intervention designed to decrease pain and disability for breast cancer patients in medically underserved areas has not been investigated.
- Trial name
- ICAN-NC (NCT04175639)
- Testing
- Mobile Health Pain Coping Skills Training (mPCST)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Duke University
Mobility Limitation, Physical Disability
Impact of More Frequent PT Services
The purpose of this study is to determine what amount of physical therapy is beneficial in the hospital setting after suffering a stroke. This study involves research.
- Conditions
- Mobility Limitation, Physical Disability, Stroke, Acute
- Trial name
- NCT04778475
- Testing
- Intensive therapy, Standard of care therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical University of South Carolina
Post-Traumatic Stress Disorder
Enhancing Equitable and Effective (E-3) Post Traumatic Stress Disorder (PTSD) Disability Assessment
This project evaluated the impact of semi-structured, standardized interviews on the initial PTSD C\&P on the examination.
- Trial name
- E-3PTSD (NCT00699660)
- Testing
- CAPS/WHODAS, Nonstructured Interview
- Where
- 11 sites in United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
Amputation of Hip and Thigh, Level Unspecified
Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Moderately active amputees may have lost their limb due to diabetes, vascular conditions, trauma, tumour or congenital causes. These amputees currently cannot benefit from having a computerised knee because of the performance…
- Trial name
- NCT02382991
- Testing
- 3C60-NMPK, NMPK-3C60
- Where
- 15 sites in Austria, France and 1 more
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Otto Bock France SNC
Acute Orthopedic Injury
Toolkit for Optimal Recovery After Orthopedic Injury
This is a multi-site randomized feasibility trial of the Toolkit for Optimal Recovery after Orthopedic Injury (TOR), a mind-body program to prevent persistent pain and disability in at-risk patients with acute orthopedic injury…
- Trial name
- TOR (NCT04973696)
- Testing
- Toolkit for Optimal Recovery after Orthopedic Injury, Minimally Enhanced Usual Care (MEUC)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Massachusetts General Hospital
Physical Disability
Weight Loss Physical Disabilities
The objective of this study is to compare weight loss (6 mos.) and maintenance (18 mos.) between an individual home visit intervention (IH) and an intervention delivered remotely via video conferencing to groups of…
- Trial name
- NCT04046471
- Testing
- enhanced Stop Light Diet, Group Remote, Individual In-Person
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Kansas Medical Center
Cerebral Palsy, Spina Bifida
The Effectiveness of Participation-focused Interventions on Body Functions of Youth With Physical Disabilities
Youth with physical disabilities face greater restrictions to participation in community-based activities than their typically developing peers, which can lead to poor health outcomes.
- Conditions
- Cerebral Palsy, Spina Bifida, Muscular Dystrophies, Musculoskeletal Disorder
- Trial name
- NCT03851107
- Testing
- Engagement in 6-week community-based activity program
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McGill University
Distal Radius Fracture, Post Operative Pain Control
Single Shot vs Catheter Infraclavicular Brachial Plexus Block After Distal Radius Fracture Repair
The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to continuous catheter nerve block done in adult patients who have under gone surgery to repair distal radius fractures.
- Trial name
- NCT02744352
- Testing
- 20ml bolus of 0.5% ropivicaine, 0.2% of ropivacaine at 8 milliliter/hour
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Disability Physical
Pilot Testing a New Pregnancy Decision Making Tool for Women With Physical Disabilities
The purpose of this project is to develop, and pilot test a decision-making tool that is tailored for women with physical disabilities to support those women in making a decision about whether or not a pregnancy is right given…
- Trial name
- NCT04651114
- Testing
- Decision-making tool
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Michigan
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Stroke, Physical Activity
Activating Behavior for Lasting Engagement After Stroke
Stroke survivors demonstrate high levels of sedentary behavior, placing them at risk for exacerbation of chronic health conditions. This may lead to recurrent stroke.
- Conditions
- Stroke, Physical Activity, Sedentary Lifestyle, Behavior, Health
- Trial name
- ABLE (NCT03305731)
- Testing
- Activating Behavior for Lasting Engagement
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pittsburgh
Physical Disability, Chronic Mental Disorder
Persons With Disabilities Generating Quality Metrics
No standard way exists to measure the quality of medical care or independent living long-term services and supports provided to persons with disabilities.
- Trial name
- NCT02390557
- Testing
- Survey, YESHealth
- Volunteers
- 451 people
- Sponsor
- Massachusetts General Hospital