Clinical trials: Disability
Developmental Delay (Disorder)
Mindful Movement And GAME BASED Training In Developmental Delay
Developmental delay in children is characterized by delayed acquisition of cognitive, motor, language, and social skills and is commonly associated with conditions such as cerebral palsy, autism spectrum disorder, and genetic…
- Trial name
- MINDGAME (NCT07575165)
- Testing
- Mindful movement, Game based training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Rett Syndrome
Esketamine for the Treatment of Rett Syndrome
The goal of this interventional study is to learn about the efficacy and safety of Esketamine for treating children with Rett syndrome (RTT).
- Trial name
- NCT06199700
- Testing
- Esketamine hydrochloride
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Children's Hospital of Fudan University
Neck Pain
Neck Motion and Motor Control in Chronic Neck Pain and Associations With Clinical Symptoms
The primary purpose of this study is to investigate if there is altered motor control of head and neck in chronic neck pain patients compared with healthy persons.
- Trial name
- NCT01778036
- Where
- 2 sites in Norway
- Volunteers
- 84 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Low Back Pain
Effect of High Intensity Interval Exercise on Chronic Low Back Pain Patients
Patients with low back pain (LBP) often report an overall reduced physical activity and fitness that could consequently lead to an altered autonomic balance.
- Trial name
- CLBP (NCT03753165)
- Testing
- High intensity interval exercise
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Myofascial Temporomandibular Disorder, Bruxism, Sleep
Factors Affecting Patients With Myofascial Temporomandibular Disorders
The aim of the study was to assess and compare the relationship between jaw function, neck disability, sleep quality, fatigue, and headache in patients with myofascial Temporomandibular Disorder (TMD) with Sleep Bruxism (SB) and…
- Conditions
- Myofascial Temporomandibular Disorder, Bruxism, Sleep, Sleep Disturbance, Jaw Spasm
- Trial name
- NCT04842136
- Testing
- Scales and indexes
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Parents, Children With Disabilities
ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics
The goal of this clinical trial is to evaluate the feasibility, usability, and preliminary benefits of implementing ACT Together for parents of children with disabilities in pediatric outpatient clinics.
- Conditions
- Parents, Children With Disabilities, Stress, Depression
- Trial name
- NCT07360600
- Testing
- ACT Together
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Fragile X Syndrome
Optical Imaging as a Tool for Monitoring Brain Function in Fragile X Syndrome
The objective of this project is to explore the potential of functional near- infrared spectroscopy (fNIRS) as innovative functional biomarker for clinical trial readiness in Fragile X Syndrome (FXS) that is still without cure.
- Trial name
- NCT06293027
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Fragile X Syndrome
A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome
A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN14770 in Male Adults (Aged 18 to 45) with Fragile X Syndrome
- Trial name
- NCT05358886
- Testing
- BPN14770/ zatolmilast
- Where
- 17 sites in United States
- Volunteers
- 171 people
- Sponsor
- Tetra Discovery Partners
Low Back Pain
Effectiveness of Coordinated Care to Reduce the Prolonged Disability Risk Among Patients Suffering From Low Back Pain in Primary Care
Common low back pain affects about 23% of general population and can be associated with psychosocial difficulties and prolonged inability to work.
- Trial name
- COLOMB (NCT04826757)
- Testing
- Coordinated care
- Where
- 20 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Angers
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Neck Pain
Prevalence of Helmet Associated Neck Pain Among TCS Riders
The aim and objective of this study is to check the prevalence of helmet associated neck pain among TCS riders.
- Trial name
- NCT07071792
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Multiple Disability
Function-oriented Assistive Technology Indexing System Development and Promotion
Appropriate assistive devices are important factors for the activity participation of the disabled. These devices should be prescribed by the specialists based on their functional needs.
- Trial name
- NCT02492971
- Where
- Taiwan
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Delay, Skeletal Abnormalities
Biomarker for Sly Disease (MPS VII) (BioSly)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Sly disease from blood (plasma)
- Conditions
- Developmental Delay, Skeletal Abnormalities, Hepatomegaly, Splenomegaly
- Trial name
- BioSly (NCT02298699)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Acute Low-back Pain, Chronic Low-back Pain
Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain
Evaluate pain and disability change in Low Back Pain with DuoTherm Compared to Active Control
- Conditions
- Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
- Trial name
- NCT04494698
- Testing
- Duotherm VibraCool Back Device, TENS 8-channel unit
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Substance Use, Severe Mental Disorder
Validation of the Dutch Translation of the Tobacco, Alcohol, Prescription Medication and Other Substances (TAPS)-Tool
The aim of the study is to investigate the reliability and validity of the Dutch version of the TAPS-tool. This will be investigated in 2 groups: patients without intellectual disabilities treated in Flexible Assertive Community…
- Conditions
- Substance Use, Severe Mental Disorder, Intellectual Disability, Mild
- Trial name
- NCT05273021
- Testing
- TAPS
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Birgit Seelen-de Lang
Non-specific Low Back Pain
Effects of Manual Lumbar and Prone Traction in Patients With Low Back Pain
The study determined the effects of manual Lumbar traction and prone traction on some clinical variables of patients with long standing low back pain.
- Trial name
- L&PtracinLBP (NCT05518552)
- Testing
- Manual lumbar traction, Prone traction
- Where
- Nigeria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Respiratory Aspiration
Acceptability and Feasibility of a New Postural Management Night-time Intervention to Improve Respiratory Health of Children With Complex Neuro-disability
This research concerns children with complex neuro-disability. Damage to the developing brain leads to lifelong disturbances in motor control, seizures, cognition, communication, eating and drinking, and behaviour.
- Trial name
- Breathe-Easy (NCT06039852)
- Testing
- Novel Postural Management Night-time Intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sussex Community NHS Foundation Trust
Vestibular Disorder, Physical Disability
Feasibility, Usability and Safety of the Vestibular Rehabilitation Using the Immersive Virtual Reality Software DizzyVR
The main goals of this pilot study is to assess the feasibility, usability, satisfaction and safety of the immersive virtual reality system called DizzyVR in participants diagnosed with a vestibular disorder.
- Trial name
- DizzyVR (NCT06350721)
- Testing
- DizzyVR
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Loyola Andalucia
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