Clinical trials: Digital Ulcer
Systemic Sclerosis, Scleroderma
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine
This study will evaluate the effect of treprostinil diethanolamine (UT-15C) sustained release tablets(compared to placebo) on digital ulcers in patients with scleroderma. Treprostinil diethanolamine is an analog of prostacyclin.
- Trial name
- DISTOL-1 (NCT00775463)
- Testing
- treprostinil diethanolamine
- Where
- 30 sites in United States, Canada and 1 more
- Volunteers
- 148 people
- Sponsor
- United Therapeutics
Scleroderma, Scleroderma, Systemic
Effectiveness of Telerehabilitation on Scleroderma
The effects of exercises performed by telerehabilitation on individuals with hand-affected scleroderma on range of motion, grip strength, function, sensation, daily life activities and general health will be compared with the…
- Conditions
- Scleroderma, Scleroderma, Systemic, Scleroderma Associated Digital Ulcer, Hand Rheumatism
- Trial name
- NCT04563481
- Testing
- Hand Therapy via Telerehabilitation, Hand Therapy by Physiotherapist
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Colitis, Ulcerative, Inflammatory Bowel Diseases
Digital Holographic Microscopy: Evaluation of Histological Disease Activity in Patients With Ulcerative Colitis
Ulcerative colitis (UC) belongs to the group of inflammatory bowel disease (IBD) and is characterized by a chronic relapsing disease course.
- Trial name
- NCT03464474
- Testing
- digital holographic microscopy
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University Hospital Muenster
Inflammatory Bowel Diseases, Ulcerative Colitis
Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT07456566
- Testing
- Digital self-management program, Standard Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Scleroderma, Systemic
Pilot Study of Description of Cicatrisation Rates of Digital Ulcers in Systemic Scleroderma
To make an updated inventory of digital ulcer care protocols in scleroderma patients and to specify the French data on monthly healing rates and local care with patients in care centers experience, and thus to know the impact of…
- Trial name
- POPSUD (NCT04319120)
- Testing
- questionnaires online
- Where
- 3 sites in France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Limoges
Venous Leg Ulcer (VLU), Chronic Wound
Smart Bandage With Telemonitoring vs Standard Care for Venous Leg Ulcer: Randomized Trial
Venous leg ulcers (VLUs) are chronic wounds that are often slow to heal and can greatly affect patients' daily lives. This study will evaluate a new "smart bandage" that can monitor wound conditions such as pH, temperature, and…
- Trial name
- SMART-VLU (NCT07163195)
- Testing
- Smart Bandage with Telemonitoring, Conventional Bandage
- Where
- Indonesia
- Volunteers
- 110 people
- Sponsor
- Asmat Burhan
Scleroderma, Systemic
The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis
The aim of the study is to investigate whether bosentan added to usual care improves arterial stiffness after 3 months as measured as the pulse wave velocity (PWV) of the medium and large arteries corrected for blood pressure…
- Trial name
- CEASESTIFF (NCT02480335)
- Testing
- bosentan
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Nursing Caries, Pressure Injuries
Virtual Escape Room Game About Medical Device in Nurses
The research was planned as a pre-test-post-test single-group, quasi-experimental design in order to develop a web-based digital education game to improve nurses' knowledge level on pressure injuries related to medical devices…
- Trial name
- NCT07081490
- Testing
- Virtual Escape Room Game
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Foot Ulcer, Diabetic, Diabetes Complications
Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot Ulcers
This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers.
- Trial name
- NCT00318214
- Testing
- MRE0094, Vehicle gel
- Where
- 19 sites in United States
- Volunteers
- 16 people
- Sponsor
- Pfizer
Systemic Sclerosis
Ultrasound Therapy and Manual Therapy in Digital Ischemic Ulcers
The objective of this before-after non-randomized trial study is to evaluate the efficacy of ultrasound therapy in combination with manual therapy in the management of systemic sclerosis patients with IDU.
- Trial name
- NCT05907200
- Testing
- combination ultrasound therapy and manual therapy, manual therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Palermo
Systemic Sclerosis
ADMSCs for the Treatment of Systemic Sclerosis
Systemic sclerosis (SSc) is a rare autoimmune disease, mainly characterized by cutaneous and visceral fibrosis. Digital ulcer and sclerosing skin are commonly affected on hands, but the treatment for these manifestations are…
- Trial name
- NCT02975960
- Testing
- injection of autologous stromal vascular fraction
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- The Catholic University of Korea
Digital Ulcer of Scleroderma
Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers
Digital ulcers are one of the most prevalent complications of scleroderma (systemic sclerosis). There can be found few surveys on effect of topical agents on healing process of the ulcers.
- Trial name
- NCT02801305
- Testing
- Diltiazem Gel 2%, Nitroglycerin Ointment 2%, Vaseline
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Mohammad Ali Nazarinia
Cholecystitis, Perforated Duodenal Ulcer
Incentive Spirometry and Upper Abdominal Laparoscopic Surgery
To compare the effects of volume-oriented versus flow-oriented incentive spirometry on pulmonary function tests and functional capacity in patients of upper abdominal laparoscopic surgery.
- Conditions
- Cholecystitis, Perforated Duodenal Ulcer, Diaphragmatic Hernia, Benign Pancreas Tumor
- Trial name
- NCT04716166
- Testing
- Volume-oriented incentive spirometry, Flow-oriented incentive spirometry
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Diabetic Foot, Diabetic Foot Ulcer
Digital Foot Check by Using the D-Foot, a New Software
Patients with diabetes should be thoroughly examined before they are provided with insoles and shoes. In the study the feet are examined with the help of a new software, the D-Foot. D-Foot includes questions and surveys.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Diabetic Foot Ulcer Neuropathic, Neuropathy;Peripheral
- Trial name
- D-Foot2019 (NCT04054804)
- Testing
- D-Foot
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Pressure Injury
Digital Multimedia in Clinical Nurse Education for Pressure Injury Prevention Via LINE@
The goal of this clinical trial is to integrate past indicators affecting the effectiveness of pressure injury care education among nurses and to explore the learning outcomes of nurses through different educational…
- Trial name
- NCT06527716
- Testing
- Teaching Strategy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Asia University
Diabetic Neuropathies
Effects of Customized Silicone Digital Orthoses in People With Diabetic Neuropathy
The present study aims to evaluate the efficacy and safety of the use of customized silicone digital orthoses for six months in the distribution of plantar pressure, in the reduction of pre-ulcerative lesions and plantar ulcers…
- Trial name
- NCT05683106
- Testing
- Custom silicone digital orthosis (CSDO)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Foot Ulcer, Diabetic, Diabetes Complications
Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers
This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers.
- Trial name
- NCT00312364
- Testing
- MRE0094
- Where
- 63 sites in United States
- Volunteers
- 322 people
- Sponsor
- Pfizer
Systemic Sclerosis, Digital Ulcers
Bosentan in Systemic Sclerosis
The effect of bosentan on digital ulcers (DU) was studied in two randomized placebo-controlled trials (RAPIDS-1 and RAPIDS-2). A limitation of these studies was the heterogeneous study population.
- Trial name
- HOME (NCT01395732)
- Testing
- Bosentan
- Where
- 10 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- Actelion
Systemic Sclerosis, Ulcer
Prevention and Treatment of Digital Ulcers in Systemic Sclerosis
Systemic sclerosis is an orphan, multiorgan disease affecting the connective tissue of the skin and several internal organs. Digital ulcers are frequent and have a major impact on the quality of life in patients with systemic…
- Trial name
- NCT01836263
- Where
- 11 sites in France, Germany and 4 more
- Volunteers
- 420 people
- Sponsor
- marco matucci cerinic
Crohn Disease (CD), Ulcerative Colitis (UC)
Multiple Digital Biomarkers for Optimization of IBD Care
To develop digital biomarkers associated with disease activity of inflammatory bowel disease
- Conditions
- Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- LEGEND-IBD (NCT07159776)
- Testing
- monitoring of wearable data, shopping data, biomarkers and patient reported outcomes
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Imelda GI Clinical Research Center