Clinical trials: Diffusion Magnetic Resonance Imaging
Breast Neoplasms, Artificial Intelligence (AI)
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement
This study is conducted under the ethics-approved project titled "Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI''.The goal of this observational study is to develop an integrated breast…
- Conditions
- Breast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance Imaging
- Trial name
- NCT07598084
- Testing
- Non-contrast breast MRI diagnostic model
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Diffusion Magnetic Resonance Imaging, Brain White Matter Diseases
Diffusion Magnetic Resonance Imaging (dMRI) in the Early Evaluation of Brain White Matter Diseases
To assess the sensitivity and accuracy of diffusion magnetic resonance imaging (MRI), including diffusion-weighted imaging (DWI) metrics, in identifying early-stage changes in brain white matter related to various white matter…
- Trial name
- NCT07108712
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- The General Authority for Teaching Hospitals and Institutes
Non-invasive Diffusion-weighted Imaging, Magnetic Resonance Cholangiopancreatography
Non-invasive Diffusion-weighted Imaging With MRCP in the Diagnosis of Neoplastic Biliary Obstruction
This study aims to evaluate the diagnostic value of non-invasive diffusion-weighted magnetic resonance imaging (DW-MRI) in detecting neoplastic biliary obstruction.
- Conditions
- Non-invasive Diffusion-weighted Imaging, Magnetic Resonance Cholangiopancreatography, Diagnosis, Neoplastic Biliary Obstruction
- Trial name
- NCT07108725
- Testing
- Magnetic Resonance Cholangiopancreatography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- The General Authority for Teaching Hospitals and Institutes
Parkinson Disease, Diffusion Magnetic Resonance Imaging
The STEREO-DBS Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation
Rationale: Deep brain stimulation (DBS) of the nucleus subthalamicus (STN) is an effective surgical treatment for the patients with advanced Parkinson's disease, despite optimal pharmacological treatment.
- Conditions
- Parkinson Disease, Diffusion Magnetic Resonance Imaging, Brain, Subthalamic Nucleus
- Trial name
- STEREO-DBS (NCT05843084)
- Testing
- 7T MRI network analysis for deep brain stimulation in Parkinson's disease
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Essential Tremor, Deep Brain Stimulation
Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET
Rationale: Deep brain stimulation (DBS) of the thalamus is an effective surgical treatment for patients with disabling essential tremor, despite optimal pharmacological treatment.
- Conditions
- Essential Tremor, Deep Brain Stimulation, Diffusion Tensor Imaging, Magnetic Resonance
- Trial name
- TREMBLE (NCT05968976)
- Testing
- Awake DBS, Asleep DBS
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Breast Cancer, Chemotherapy Effect
The Prediction Model of NAC Response for Breast Cancer Based on The Parametric Dynamics Features.
The main purpose of this study is to develop a computer-aided prediction model for NAC treatment response. Based on the heterogeneity of internal parametric tumor composition commonly observed, this study will utilize the…
- Conditions
- Breast Cancer, Chemotherapy Effect, Diffusion Weighted MRI, PET Imaging
- Trial name
- NCT06370234
- Testing
- Whole body 18F-FDG Positron Emission Tomography
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Lumbar Radiculopathy, Magnetic Resonance Imaging
Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Lumbar Radiculopathy, Magnetic Resonance Imaging, Diffusion Tensor Imaging
- Trial name
- DiTi-Aïe (NCT04507113)
- Testing
- DTI sequence acquisition
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Lille Catholic University
Breast Carcinoma; Magnetic Resonance Imaging; Diffusion Spectrum Imaging
Quantitative Assessment of Diffusion Spectrum Imaging in Breast Cancer
This project intends to prospectively collect patients with suspected breast malignant tumors by ultrasound or mammography. After routine MRI scanning, all patients underwent diffusion spectrum imaging (DSI) sequence scanning.
- Trial name
- NCT05159323
- Testing
- Diffusion Spectrum Imaging
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Xiang Zhang
Bladder Cancer, Diagnoses Disease
Role of 3 Tesla Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) for Diagnosis Bladder Cancer Grade and Stage
assess diagnostic performance of 3-Tesla DW-MRI in detecting and staging bladder cancer and potential role of the ADC value as a biomarker reflecting histological grade and stage.
- Conditions
- Bladder Cancer, Diagnoses Disease, Magnetic Resonance Imaging, Apparent Diffusion Coefficient
- Trial name
- NCT03138837
- Testing
- Magnetic resonance imaging
- Where
- Egypt
- Volunteers
- 385 people
- Sponsor
- Mansoura University
Multiple Sclerosis, Dimethyl Fumarate, Diffusion Tensor Imaging Magnetic Resonance Imaging
Tecfidera Diffusion Tensor Imaging
The primary aim of this study is to explore the effect of dimethyl fumarate on gray matter (GM) pathology, as measured by changes in diffusion-tensor imaging (DTI) of the thalamus in patients with relapsing multiple sclerosis…
- Trial name
- DTI (NCT02686684)
- Testing
- Dimethyl fumarate
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Whole Body Imaging, Magnetic Resonance Imaging
Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Whole body MRI will be performed in patients with neurofibromatosis Type 1 PURPOSE 1: To determine the total tumor load (neurofibroma) and to diagnose plexiform neurofibromas or malignant peripheral nerve sheath tumors.
- Conditions
- Whole Body Imaging, Magnetic Resonance Imaging, Neurofibromatosis 1, Diffusion Magnetic Resonance Imaging
- Trial name
- NEFIMAR (NCT01777451)
- Testing
- Additional imaging or surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven