Clinical trials: Differential Lung Ventilation
Respiratory Distress Syndrome
Predictive Value of PS Application in Premature Infants With RDS
A multicenter prospective study was conducted to compare the predictive value of 6-zone, 10-zone, and 12-zone LUS scores for PS application in early and late preterm infants.
- Trial name
- NCT05772247
- Testing
- Lung ultrasound
- Volunteers
- 1,392 people
- Sponsor
- The First Hospital of Jilin University
Thrombosis, Nadroparin
Nadroparin Pharmacokinetics in Different Stages of COVID-19
Objective: The risk of thrombotic complications in critical COVID-19 patients remains extremely high, and multicenter trials failed to prove the survival benefit of escalated doses of low molecular weight heparins (LMWH) in this…
- Conditions
- Thrombosis, Nadroparin, COVID-19, Mechanical Ventilation
- Trial name
- NCT05621915
- Testing
- Nadroparin
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Medical University of Lublin
Chest--Diseases
Clinical Application and Outcome of Non-invasive Ventilation in Different Chest Diseases
Noninvasive ventilation is increasingly used method of respiratory management in both the emergency room and critical care. Noninvasive ventilation delivers mechanically assisted breaths without the placement of an artificial…
- Trial name
- NCT03169452
- Testing
- Non-invasive mechanical ventilator
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Respiration, Artificial, Energy Metabolism
Energy Expenditure in Weaning From Mechanical Ventilation
During weaning from mechanical ventilation process, the energy expenditure in T tube is greater than pressure support ventilation.
- Trial name
- NCT00853060
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Respiration; Insufficient or Poor, Newborn
Mask Ventilation With Different Face Masks During Neonatal Resuscitation
Most premature babies have difficulty breathing at birth and need help (what we call resuscitation). The treatment for this is to gently inflate their lungs with a resuscitation device and a facemask.
- Trial name
- NCT01685697
- Testing
- Mask ventilation with a Laerdal face mask, Mask ventilation with a F&P face mask
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Inadequate or Impaired Respiratory Function
The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers
Investigation of the differences between the levels of extracellular and intracellular nano-particles in workers exposed to environmental particles during their employment to enhance understanding the process of penetration of…
- Trial name
- Nanoexposure (NCT01599845)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Respiratory Distress Syndrome, Mechanical Ventilation, Respiratory Mechanics, Ventilator-induced Lung Injury
A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies
Ventilator-induced lung injury is a common complication. The latest and most noticeable theory of its pathogenesis is called 'ergotrauma' by Gattinoni in 2016.
- Trial name
- NCT04046380
- Testing
- work of breath measurement and calculation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Changhua Christian Hospital
COVID-19 Pneumonia, Non-invasive Ventilation
The Difference Between Non-invasive High-frequency Oscillatory Ventilation and Non-invasive Continuous Airway Pressure Ventilation in COVID-19 With Acute Hypoxemia
High frequency oscillatory ventilation (HFOV), as an ideal lung protection ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute…
- Trial name
- NCT05706467
- Testing
- Non-invasive high-frequency oscillatory ventilation, Non-invasive continuous positive airway pressure ventilation
- Volunteers
- 20 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Rigid Bronchoscopy Ventilation
Clinical Effects of Different Ventilation Strategies in Rigid Bronchoscopy Procedures
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures.
- Trial name
- RBV-HFJV (NCT07860918)
- Testing
- Jet Ventilation, Spontaneous Assisted Ventilation
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Coronary Artery Bypass
Noninvasive Ventilation After Coronary Bypass Grafting
This is a prospective, quantitative, randomized, crossover study. Were included in this study 10 people in the Intensive Care Unit at University Hospital in Uberlandia, on the first day of the postoperative coronary artery bypass…
- Trial name
- Physiotherapy (NCT02352376)
- Testing
- Conventional ventilator, Specific ventilator
- Volunteers
- 10 people
- Sponsor
- Federal University of Uberlandia
Respiratory Physiology, Respiratory Insufficiency
Investigation of Efficiency of Breathing With Different Breathing Patterns
Our aim in this study is to investigate the efficiency of the breathing with different breathing patterns. Ten volunteers and twenty patients having respiratory problems will be coached on their breathing through specific masks…
- Conditions
- Respiratory Physiology, Respiratory Insufficiency, Breathing Patterns
- Trial name
- NCT00784004
- Testing
- Breathing Patterns
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
One Lung Ventilation, Continuous Positive Airway Pressure
Differential Lung Ventilation vs. CPAP
In this study we compared the efficacy of continuous positive airway pressure (CPAP) to differential lung ventilation, in terms of patient's oxygenation, during video assisted thoracoscopic lung resection.
- Conditions
- One Lung Ventilation, Continuous Positive Airway Pressure, Differential Lung Ventilation
- Trial name
- NCT03563612
- Testing
- cpap
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Rambam Health Care Campus
High Flow Oxygen Therapy, Non Invasive Ventilation (NIV)
Predicting the Need for Invasive Mechanical Ventilation Using Different Risk Scores
This prospective, single-center observational study aims to evaluate the predictive performance of the ROX index, modified ROX index, and HACOR score for the need for invasive mechanical ventilation in adult intensive care unit…
- Trial name
- HFNC-NIV (NCT07896616)
- Volunteers
- 84 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Chronic Obstructive Pulmonary Disease (COPD), Whole Body Vibration
Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance.
- Trial name
- NCT07509606
- Testing
- Whole body vibration
- Where
- Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
COPD Exacerbation, Pneumonia
Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows
The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2).
- Conditions
- COPD Exacerbation, Pneumonia, Hypoxemia, Respiratory Disease
- Trial name
- NCT05819164
- Testing
- Masimo oximeter, Nellcor oximeter, Nonin oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Community-acquired Pneumonia, Acute Respiratory Distress Syndrome
Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia
Randomized Controlled Trial Comparing Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia. The control strategy will be based on ARDSNet approach.
- Trial name
- STAMINA (NCT04972318)
- Testing
- Positive end-expiratory pressure titration with driving pressure control, ARDSNet ventilatory strategy
- Where
- 6 sites in Brazil
- Volunteers
- 214 people
- Sponsor
- Hospital do Coracao
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Pursed-Lip Breathing With Different I:E Ratios on Respiratory Outcomes in COPD Patients
The goal of this clinical trial is to evaluate whether different inspiratory-expiratory (I:E) ratios in the pursed-lip breathing (PLB) technique can improve respiratory outcomes in patients with stable Chronic Obstructive…
- Trial name
- PLB I:E Ratio (NCT07573826)
- Testing
- Participants perform PLB with inspiratory-expiratory ratio 1:3 (2 seconds inspiration, 6 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:4 (2 seconds inspiration, 8 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:5 (2 seconds inspiration, 10 seconds expiration)
- Volunteers
- 122 people
- Sponsor
- Scholastica Fina Aryu Puspasari
Ventilator-Induced Lung Injury, Acute Respiratory Distress Syndrome
Comparing Mechanical Power in Different Inspiratory Times
We aimed to compare mechanical power and energy values using geometric methods at varying inspiratory rise times.
- Trial name
- NCT06413472
- Testing
- Mechanical ventilator adjustment for PCV, Mechanical ventilator adjustment for VCV
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
to Assess the Corresponding PEEP Values in NIV With CPAP Under Different Airflow Rates During HFOT in Heart Failure Patients
Using Electrical Impedance Tomography to Investigate the Relationship Between Airflow Rate During High-flow Oxygen Therapy and Pressure in Patients With Heart Failure Compared to Non-invasive Ventilation
Non-invasive ventilation (NIV) has been widely used in heart failure patients with supporting evidence. However, the drawbacks and contraindications associated with NIV limit its applicability in certain patients.
- Trial name
- NCT06107907
- Testing
- Non-invasive ventilation (NIV) or high-flow oxygen therapy (HFOT) using electrical impedance tomography (EIT)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Emergence Agitation
Effect of Induction Method in Post Operative Agitation
To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy
- Trial name
- NCT03252405
- Testing
- mask ventilation, intravenous cannulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital