Clinical trials: Dietary Sugars
Type 2 Diabetes
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
This study will look at how much CagriSema helps participants with type 2 diabetes lower their blood sugar and body weight. CagriSema is a new investigational medicine. Doctors may not yet prescribe CagriSema.
- Trial name
- REIMAGINE 1 (NCT06323174)
- Testing
- Cagrilintide, Semaglutide
- Where
- 50 sites in United States, China and 5 more
- Volunteers
- 189 people
- Sponsor
- Novo Nordisk A/S
Healthy
Added Sugar Intake, Sweet Taste Phenotypes and Biomarkers
The goals of this cross-sectional study on a racially diverse group of children (3-10y) and their mothers are to determine whether the relationship between sweet taste phenotypes differed among mother-daughter and mother-son…
- Trial name
- SWBIO (NCT05047588)
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Dietary Habits, Endotoxemia
Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function
The aim of the present study is to determine the effect of non-nutritive sweeteners on intestinal barrier function and inflammatory markers in healthy subjects in comparison to mono- and disaccharides.
- Trial name
- NCT04788680
- Testing
- Dietary intervention 1, Dietary Intervention 2, Dietary Intervention 3
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Diet, Healthy
Understanding Food Choices in Saudi Arabia- Taxes
Using a 3-arm randomized controlled trial, the investigators aim to rigorously evaluate the effects of two different taxation policies on diet quality.
- Trial name
- NCT05429528
- Testing
- Implicit Tax, Explicit Tiered Tax
- Where
- Singapore
- Volunteers
- 2,490 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Cardiovascular Disease, Diabetes
Diet and Activity Promotion Among Older Working Adults
The trial will test whether the Alive email-delivered health behavior program can improve subjects' physical activity, fruits and vegetables and saturated/trans fats and added sugars.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Aging
- Trial name
- ALIVE (NCT01233063)
- Testing
- Physical Activity and Diet Intervention via Alive2
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Berkeley Analytics, Inc.
Healthy, Overweight and Obesity
Strategies To OPpose Sugars With Non-nutritive Sweeteners Or Water (STOP Sugars NOW) Trial
Health authorities recommend a reduction in added sugars from sugar-sweetened beverages (SSBs) due to risk of obesity and diabetes. As a sugar-reduction strategy, finding the ideal SSB replacement is of the utmost importance.
- Conditions
- Healthy, Overweight and Obesity, Metabolic Syndrome, PreDiabetes
- Trial name
- NCT03543644
- Testing
- Sugar-sweetened beverage (SSB), Non-nutritive sweetened beverages (NSB), Water
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer, Breast Cancer Stage IV
Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer
The purpose of this study to find out whether a very low carbohydrate diet (ketogenic diet), a low carbohydrate diet, or the study drug canagliflozin can prevent high blood sugar and may improve the effectiveness of cancer…
- Conditions
- Breast Cancer, Breast Cancer Stage IV, Metastatic Breast Cancer
- Trial name
- NCT05090358
- Testing
- Ketogenic Diet, Low Carbohydrate Diet, Alpelisib
- Where
- 9 sites in United States
- Volunteers
- 15 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Child Development
Added Sugar Intake and Brain Structure and Function
The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.
- Trial name
- GAINS BRAINS (NCT06640829)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Obesity, Adolescent, Dietary Sugars
A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents
The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black/African American and Latine adolescents with obesity…
- Conditions
- Obesity, Adolescent, Dietary Sugars, Taste Perception, Insulin Resistance
- Trial name
- SPARKLE (NCT07223151)
- Testing
- Unsweetened Sparkling Water Replacement, Progressively Reduced Sugar Beverage Replacement, Plain Water Replacement
- Where
- 3 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Nana Gletsu Miller
Unhealthy Diet
Reduction of Excessive Calories From Beverages in Children
Objective: to test the hypothesis that an intervention comprised of targeted physician and print messages can influence parents to reduce the amount of sugar-sweetened beverages (SSB) and fruit juice they give to their children 1…
- Trial name
- MWP (NCT02239653)
- Testing
- Physician communication
- Where
- United States
- Volunteers
- 443 people
- Sponsor
- Washington University School of Medicine
Dietary Behaviour
Reducing Free Sugar Intakes: A Role for Sweet Taste
This randomised controlled trial aims to assess the effects of three different types of dietary advice for reducing free sugar intakes, on intakes of free sugar, in a sample of the UK population.
- Trial name
- NCT05684757
- Testing
- Dietary Advice
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Sugar; Blood, High
The Acute Effect of D-allulose Consumption on Postprandial Glycaemia
The rare sugar D-Allulose, when consumed in a drink before eating has been shown to reduce the blood glucose response to high carbohydrate drinks or meals in people who are healthy, or have elevated fasting blood glucose…
- Trial name
- NCT06330636
- Testing
- D-Allulose, Sodium Saccharin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aging, Diet, Healthy
Western Diet on Cardiometabolic and Immune Function
This study will implement a Western Diet (WD) to understand cardiometabolic and immune function in middle-aged adults (50- 64 years old).
- Trial name
- WD (NCT06528977)
- Testing
- Western Diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Fibromyalgia
Anti-inflammatory Nutritional Intervention in Patients With Fibromyalgia
This is a randomized clinical trial, aimed to analyse the effects of a potentially anti-inflammatory nutritional intervention in disease assessment parameters, inflammatory markers, and quality of life of Fibromyalgia patients.
- Trial name
- NCT04007705
- Testing
- Anti-inflammatory and low FODMAPs diet, General healthy eating
- Where
- Portugal
- Volunteers
- 46 people
- Sponsor
- Universidade do Porto
Hypertriglyceridaemia
Understanding Liver Fat Metabolism: Studies to Understand the Role of Dietary Sugars on Liver Fat Metabolism
High levels of fatty substances in the blood increase the risk of developing coronary heart disease and having a heart attack. The investigators know a lot about one of these fatty substances, cholesterol.
- Trial name
- NCT02478541
- Testing
- Sugar study
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Weight Loss
Resistant Starch and Whey Protein on Energy Metabolism
Recent evidence shows that dietary supplementation with resistant starch (RS) increases fat catabolism and resting energy expenditure and decreases plasma insulin and glucose responses as well as the gut-derived hormone…
- Trial name
- NCT02418429
- Testing
- waxy maize starch, waxy maize starch and Whey Protein, Resistant Starch
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Diabetes Mellitus
Effect of Varying the Protein and Dietary Fiber Content of Energy Bars on Their Glycemic and Insulinemic Impact
The purpose of this study was to determine the effect of changing the amounts of resistant starch, whey protein and sugar on the blood glucose and insulin responses elicited by energy bars.
- Trial name
- Solstice (NCT02537587)
- Testing
- Control 1, Control 2, 15/0
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Chronic Disease, Obesity
Evaluation of the Impact of a Sugar-Sweetened Beverage Tax in Chile
The purpose of this study is to evaluate formally the short term impacts of the tax policy applied to Sugar-Sweetened Beverages (SSBs) in Chile.
- Trial name
- NCT02926001
- Volunteers
- 2,836 people, healthy volunteers welcome
- Sponsor
- Marc Suhrcke
Dietary Behaviour, Nutrition Knowledge
Added-Sugars Warning Label PSAs
The purpose of this study is to determine if exposure to language-matched English-Spanish public service announcements (PSAs) can increase the understanding of and response to added-sugars menu warning labels among U.S.
- Conditions
- Dietary Behaviour, Nutrition Knowledge, Perceptions
- Trial name
- NCT07791511
- Testing
- Labels are coming soon, Hidden sugars in restaurant foods, Negative health outcomes
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Dietary Habits
Impact of Warnings on Sugar-Sweetened Beverages
The purpose of this randomized controlled trial is to determine whether pictorial warnings on sugar-sweetened beverages are more effective than neutral labels at reducing parents' purchases of sugar-sweetened beverages for their…
- Trial name
- NCT04223687
- Testing
- Sugar-Sweetened Beverage Warning Label, Neutral label
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill