Clinical trials: Diaphragm Defect
Hernias, Diaphragmatic, Congenital, Hernia; Diaphragm Defect, Congenital
Physiological-based Cord Clamping in Congenital Diaphragmatic Hernia
Pulmonary hypertension is a major determinant of postnatal survival in infants with a congenital diaphragmatic hernia (CDH). The current care during the perinatal stabilisation period in infants born with this rare birth defect…
- Conditions
- Hernias, Diaphragmatic, Congenital, Hernia; Diaphragm Defect, Congenital, Pulmonary Hypertension
- Trial name
- PinC (NCT04373902)
- Testing
- Physiological-based cord clamping
- Where
- 9 sites in Australia, Austria and 5 more
- Volunteers
- 144 people
- Sponsor
- Erasmus Medical Center
Pulmonary Hypertension of Newborn, Diaphragm Defect
Effect of a Parenteral Emulsion With Omega3 on Neonates With PPHN and CDH
The purpose of this study is to evaluate the effect of a parenteral emulsion containing n-3 long-chain polyunsaturated fatty acids (LC-PUFA) in fish oil on clinical outcomes, markers of inflammation and oxidative stress, and pain…
- Trial name
- CDH-PPHN-N3 (NCT04031508)
- Testing
- lipid injectable emulsion with Fish oil
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Weaning Failure, Diaphragm Defect
Value of Diaphragm Function Predicting Weaning From Mechanical Ventilation
The reason of failure of weaning from mechanical ventilation is that their respiratory loads exceeding the capacity of their respiratory muscles.
- Trial name
- NCT05632822
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peking Union Medical College Hospital
Systemic Sclerosis, Diaphragm Defect
Muscular Respiratory Involvement and Systemic Sclerosis
Dyspnea in systemic sclerosis (ScS) constitute a major factor of functional disability. Intensity of dyspnea is sometimes discordant with objectives data from cardiopulmonary involvements, suggesting unknown additional factors.
- Conditions
- Systemic Sclerosis, Diaphragm Defect, Respiratory Insufficiency, Pulmonary Function Test
- Trial name
- SIROCO (NCT04118725)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Poitiers University Hospital
Sepsis, Disease of Diaphragm
Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis
Diaphragmatic dysfunction is associated with sepsis severity and pejorative prognosis. Aim of this study is to assess diaphragmatic function with the Diaphragmatic Thickening Fraction (DTF) ultrasound measure in patients with…
- Conditions
- Sepsis, Disease of Diaphragm, Defect of Diaphragm, Intensive Care Neuropathy
- Trial name
- US-Diamonds (NCT02474797)
- Testing
- Diaphragmatic ultrasonography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Hôpital Saint-Joseph