Clinical trials: Diabetic Foot Disease
Diabetes, Foot Ulcer
Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers
After determining if subjects meet the criteria to be included in the study they will be randomly placed in either Group 1 or 2 and patient will be blinded from randomization group.
- Trial name
- NCT01108263
- Testing
- INTEGRA™ Flowable Matrix (Collagen)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Diabetic Foot
Diabetic Foot Ulcer Study on Topical Interventions
The purpose of this study is to determine whether nanocrystalline silver dressing, manuka honey dressing and conventional dressing are effective in the treatment of diabetic foot ulcer.
- Trial name
- DFU (NCT02577900)
- Testing
- Acticoat absorbent, Honey gel sheet, Jelonet
- Volunteers
- 31 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Peripheral Arterial Disease, Diagnosis
DIAbetes Maximal ACCeleration
Prevalence of diabetes mellitus (DM) is increasing rapidly, with patient numbers projected to rise to 643 million by 2030. As a consequence of diabetes-related atherosclerosis, peripheral arterial disease (PAD) and in particular…
- Conditions
- Peripheral Arterial Disease, Diagnosis, Diabetic Foot
- Trial name
- DIAMACC (NCT05646147)
- Testing
- Maximal Systolic Acceleration
- Volunteers
- 238 people
- Sponsor
- Leiden University Medical Center
Diabetic Foot Ulcer
BST-DERMON Versus Standard of Care in the Treatment of Diabetic Foot Ulcers
This trial is designed to investigate the therapeutic benefits of using BST-DermOn for the wound repair of diabetic neuropathic foot ulcers.
- Trial name
- NCT00434538
- Testing
- BST-DermOn
- Where
- 20 sites in Canada
- Volunteers
- 40 people
- Sponsor
- BioSyntech Canada Inc.
Diabetic Foot
Cost-effectiveness Evaluation of Two 10% Urea Creams in Patients With Diabetic Foot Syndrome
Randomised, double-blind, cost-effectiveness clinical trial of two 10% urea creams purchased in pharmacies and supermarkets in patients with diabetic foot syndrome.
- Trial name
- NCT05588258
- Testing
- Participants were given the 10% urea cream purchased in pharmacy or supermarket as appropriate after randomisation and their foot skin quality was assessed by validated questionnaire.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Complutense de Madrid
Foot Ulcer, Diabetic, Diabetes Complications
Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers
This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers.
- Trial name
- NCT00312364
- Testing
- MRE0094
- Where
- 63 sites in United States
- Volunteers
- 322 people
- Sponsor
- Pfizer
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Diabetic; Foot Ulcers
Allogenic Dermis Versus Standard Care in the Management of Diabetic Foot Ulcers
This is comparison trial comparing human dermis to standard wound care for non healing diabetic wound
- Trial name
- NCT02331147
- Testing
- Offloading, Dressing Application
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Musculoskeletal Transplant Foundation
Diabetic Foot Ulcer
Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
The purpose of this study is to determine whether the EpiFix human amniotic membrane is effective in the treatment of diabetic foot ulcers.
- Trial name
- NCT01552499
- Testing
- Standard of care, Applications of EpiFix
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- MiMedx Group, Inc.
Diabetic Foot Ulcers
Passive Training as a Treatment for Diabetic Foot Ulcers
Overall project design: This PhD project involves a randomized study on diabetic individuals with healing resistant wounds, comparing the effect of passive movement of the lower limb with standard treatment of diabetic wounds.
- Trial name
- NCT02785198
- Testing
- Passive knee extensor machine
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Vascular Ulcer (Arterial or Venous Including Diabetic Ulcers Not Located on the Foot), Diabetic Foot Ulcer
A Pilot Study to Assess the Efficacy of NEOX® CORD 1K® in the Treatment of Complex Diabetic Wounds
Patients presenting to Johns Hopkins with a diabetic ulcer classified by the UT Grade 2 or 3 who meet all of the inclusion and none exclusion criteria and give their informed consent, will receive an application of NEOX CORD 1K…
- Conditions
- Vascular Ulcer (Arterial or Venous Including Diabetic Ulcers Not Located on the Foot), Diabetic Foot Ulcer, Diabetic Foot, Diabetic Foot Infection
- Trial name
- NCT03296436
- Testing
- NEOX® CORD 1K®
- Sponsor
- Johns Hopkins University
Diabetic Foot
Diabetic Foot School and Biomechanics
The primary aim of the study is to establish a diabetic foot school. The secondary aim is to compare the effects of the training given to diabetic foot patients within the scope of the diabetic foot school, on sensory, balance…
- Trial name
- NCT05431660
- Testing
- education and exercise protocol about diabetic foot, control group
- Volunteers
- 50 people
- Sponsor
- Ankara Yildirim Beyazıt University
Diabetic Foot Ulcer, Venous Leg Ulcer
Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers
The purpose of this study is to determine how well multiple CAMPs (Cellular, Acellular and Matrix-Like Products) and Standard of Care work when compared to Standard of Care alone in achieving complete closure of diabetic foot and…
- Trial name
- CAMPLIFE (NCT06562296)
- Testing
- Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 292 people
- Sponsor
- Cellution Biologics
Diabetic Foot, Educational Intervention
Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.
There are multiple studies conducted in Pakistan that supports the topic of foot care knowledge among individual with type 2 diabetes but all are descriptive cross-sectional studies and investigators cannot develop cause effect…
- Conditions
- Diabetic Foot, Educational Intervention, Foot Care, Foot Ulcer, Diabetic
- Trial name
- NCT06358846
- Testing
- Self-care behavior to promote foot care through educational guidance among individual with diabetes
- Where
- Pakistan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SINA Health Education and Welfare Trust
Diabetic Peripheral Neuropathy
Exercise Effects on Pain, Sleep and Depression in Diabetic Peripheral Neuropathy
It is known that the pain experienced by individuals with diabetic neuropathy negatively impacts sleep and quality of life, leading to numerous psychosocial problems such as anxiety and depression.
- Trial name
- NCT07291596
- Testing
- Ankle-Foot Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Amasya University
Reflexology, Type 2 Diabetes
Effect of Reflexology on Diabetic Foot and Glycemic Control in Elderly Diabetic Individuals
Background: Glycemic control can be difficult in the elderly with diabetes.Diabetic foot problems characterized by vascular and neuropathy are serious complications.
- Conditions
- Reflexology, Type 2 Diabetes, Older People
- Trial name
- NCT04416503
- Testing
- Foot reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Foot Ulcer, Diabetic
The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals With Diabetic Foot Ulcers
The rise in diabetes incidence has led to a corresponding increase in diabetes-related complications. Diabetic foot ulcers, a severe consequence of diabetes, have substantial impacts on patients, the social environment, overall…
- Trial name
- NCT06023810
- Testing
- Watson's human care theory-based motivational interviewing method
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Okan University
Diabetic Foot Ulcer
Clinical and Mechanistic Study of Transverse Tibial Transport in Complex Foot Ulcers
TTT is a novel surgical technique that may potentially solve the long-standing deficit of seeking effective treatment for diabetic foot ulcers, decreasing the need for amputations and softening the socio-economic impact it…
- Trial name
- NCT05704075
- Testing
- Transverse Tibial Transport (TTT), Conventional
- Volunteers
- 54 people
- Sponsor
- Chinese University of Hong Kong
Diabetic Polyneuropathy
Combined Effects of Foot-Ankle Therapeutic Exercises and Mindful Walking in Patients With Diabetic Polyneuropathy
The aim of this study is to investigate the combined effects of foot ankle therapeutic exercises and mindful walking on pain, foot and ankle disability, and quality of life in patients with diabetic polyneuropathy.
- Trial name
- NCT07248631
- Testing
- Foot-Ankle therapeutic exercises and Mindful Walking., Standard care with Mindful walking.
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Diabetic Foot Ulcers, Diabetic Foot Wounds
Using Santyl on Diabetic Foot Ulcers
Subjects enrolled in this study will either use Santyl daily or follow standard care procedures for up to 6 weeks for their diabetic foot wound.
- Trial name
- NCT01408277
- Testing
- Santyl, Control
- Where
- 7 sites in United States
- Volunteers
- 55 people
- Sponsor
- Healthpoint
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