Clinical trials: Diabetes Type II
Type 2 Diabetes, Aging
IH, Brain Health, and T2D
The purpose of this study is to use a randomized, placebo-controlled study design to rigorously examine the therapeutic potential of intermittent hypoxia (IH) for improving cerebrovascular health in older adults with and without…
- Trial name
- NCT07173543
- Testing
- Intermittent Hypoxia 1 (IH1), Intermittent Hypoxia 2 (IH2)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Darren P Casey
Type2 Diabetes
Risk Assessment of Type 2 Diabetes in Pharmacies
Background: Due to lack of clear symptoms, type 2 diabetes can remain undetected for many years. Our aim was to explore the capacity of Norwegian community pharmacies to identify people at high risk of developing type 2 diabetes…
- Trial name
- NCT03979768
- Testing
- Diabetes risk assessment service in Norwegian community pharmacies
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Type 2 Diabetes Mellitus
30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)
A 30-week extension to a 24-week study assessing the hemoglobin A1c (HbA1c)- and fasting plasma glucose (FPG)-lowering efficacy of the combination of sitagliptin and pioglitazone in patients with type 2 diabetes mellitus (T2DM)…
- Trial name
- NCT01028391
- Testing
- Sitagliptin 100 mg q.d.+ Pioglitazone 45 mg q.d., Metformin
- Volunteers
- 317 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes
Diabetes Self-Management Models to Reduce Health Disparities
To evaluate the effectiveness of two different diabetes self-management approaches (Personal Digital Assistant-based intervention \& Chronic Disease Self-Management Program) to reduce health disparities in minority, rural…
- Trial name
- P20-P2 (NCT01221090)
- Testing
- PDA, CDSMP, PDA/CDSMP
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Diabetes Mellitus, Type 2
Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin
Metformin may have complex interactions in the gut and is generally first line therapy for type 2 diabetes mellitus (T2DM). It is important to understand whether there are significant pharmacokinetic or pharmacodynamic…
- Trial name
- NCT01929863
- Testing
- GSK2330672, Metformin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
Diabetes
Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes
The investigators designed this prospective, randomized control study to compare the efficacy and safety between the basal insulin glargine therapy and metformin-based OADs after correction of the glucose toxicity with a short…
- Trial name
- NCT00978263
- Testing
- metformin-based Oral Antidiabetic Drugs, Glargine
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Chongqing Medical University
Diabetes
Promoting Physical Activity in Patients With Type 2 Diabetes (DIAfit)
The aim of this study is to evaluate the effects of a physical activity intervention in patients with type 2 diabetes in a community setting.
- Trial name
- DIAfit (NCT01289587)
- Testing
- Physical activity intervention
- Where
- Switzerland
- Volunteers
- 185 people
- Sponsor
- University of Lausanne Hospitals
Type 2 Diabetes Mellitus in Obese
REmote SUpport for Low-Carbohydrate Treatment of Type 2 Diabetes
Excess adiposity is a key causal factor in developing type 2 diabetes and weight loss improves glycaemia and can put diabetes in to remission. There is evidence that low carbohydrate diets also reduce glycaemia.
- Trial name
- RESULT (NCT04916314)
- Testing
- Low Carbohydrate diet
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- University of Oxford
Diabetes Mellitus, Non-Insulin-Dependent
Clinical Trial With Broccoli Sprout Extract to Patients With Type 2 Diabetes
Type 2 diabetes (T2D) results from a combination of insufficient insulin secretion from pancreatic islets and insulin resistance of target cells.
- Trial name
- NCT02801448
- Testing
- sulforaphane
- Volunteers
- 103 people
- Sponsor
- Anders Rosengren, MD PhD
Wound Healing, Diabetic
Effect of Supplementation With HMB and Glutamine in Wound Healing on Bloody Areas
A randomized controlled clinical trial in two groups of supplementation with HMB and glutamine. Each group consist in 25 patients with bloody areas, one group will receive and intervention with HMB and Glutamine and the other…
- Trial name
- NCT03782155
- Testing
- glutamine supplementation, HMB
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital General de Mexico
Diabetes, Type 2 Diabetes
Efficacy and Safety of LC-Z300-01 in Chinese With Type 2 Diabetes
This trial is conducted in China. The aim of the trial is to investigate the efficacy and safety of an Bamboo cane polysaccharide (oral LC-Z300-01) in subjects with type 2 diabetes.
- Trial name
- NCT06847178
- Testing
- Low-dose LC-Z300-01 twice daily in blinding, High-dose LC-Z300-01 twice daily in blinding, High-dose LCZ300-1 twice daily in open-label
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Changzheng Hospital
Diabetes Mellitus, Type 2
Incidence of Type 2 Diabetes in the di@Bet.es Study
Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population.
- Trial name
- NCT02542735
- Where
- Spain
- Volunteers
- 2,408 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Type 2 Diabetes
TREAT (Telemedicine for Reach, Education, Access, and Treatment)
The purpose of this study is to evaluate the feasibility and clinical efficacy of an innovative care model that combines Telemedicine consultations, educator therapeutic management and diabetes education to empower patients to be…
- Trial name
- TREAT (NCT01339208)
- Testing
- Telemedicine diabetes intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pittsburgh
Diabetes Mellitus Type 2
Effect of High Intensity Interval Training and Ultrasound Cavitation on Lipid Profile in Type 2 Diabetes Patients
The study aim to find out the combined effect of high intensity interval training and ultrasound cavitation on lipid profile in type two diabetic patient with abdominal obesity.
- Trial name
- Diabeties (NCT06926725)
- Testing
- Cavitation : Study group A only will receive one session per week for three months (total 12 sessions ). Ultrasound treatments are performed using an applicator head with diameter 7 cm . Intensity :, high intenisty exercise, Diet
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Mahmoud Awad Ramadan Elkholy
Type 2 Diabetes Mellitus, Overweight
Impact of Liraglutide on Sensory Perception, Sensory Specific Satiety, Liking and Wanting in Type 2 Diabetic Patients
Besides their potential action in the treatment of type 2 diabetes mellitus (T2DM), GLP-1 analogues decrease satiety and food intake leading to a significant weight loss in patients.
- Trial name
- NCT01599338
- Testing
- Liraglutide
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes Mellitus, Type 2
Effects on Insulin Resistance With Tadalafil in Type 2 Diabetes - a Double-blind, Placebo-controlled Crossover Study
The aim is to continue our program on PDE5 inhibition by evaluating effects on insulin resistance, including glucose metabolism and subclinical inflammation, after a 6-week administration of tadalafil in T2D patients.
- Trial name
- MAKROTAD (NCT02601989)
- Testing
- Tadalafil
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Göteborg University
Diabetes Mellitus, Type 2
Multiple Dose Escalation Trial Of PF-04603629 Given To Subjects With Type 2 Diabetes Mellitus
PF-04603629 is being investigated for the treatment of Type 2 diabetes mellitus (T2DM). Specifically, PF-04603629 is a protein that is a combination of exendin-4 (a glucagon-like peptide-1 (GLP-1) mimetic currently marketed as…
- Trial name
- NCT00637338
- Testing
- PF-04603629
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Pfizer
Vascular Function, Exercise Training
Evaluation of Effects of Exercise Training and ARB in DM Patients
The aims of this clinical trial are to assess the impacts on vascular function tests and circulating biomarkers of a short-term (12-week) low-to-median intensity exercise training or ARBs treatment in patients with DM and…
- Trial name
- NCT01053026
- Testing
- olmesartan
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital
Type 2 Diabetes Mellitus
Premature Aging and Type 2 Diabetes Mellitus: an Increased Risk of Cardiomyopathy?
The potential clinical implications of this study are to optimise the selection of a population at risk for developing a diabetic cardiomyopathy among diabetic patients in order to develop early therapeutic strategies to prevent…
- Trial name
- R2D2 (NCT01536808)
- Testing
- Cardiac RMI, Analysis telomere, Stress test
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906640)
- Testing
- (IRIS-CKD Management Program): Education, (IRIS-CKD Management Program): GDMT
- Where
- 7 sites in United States
- Volunteers
- 212 people
- Sponsor
- Duke University