Clinical trials: Diabetes Mellitus (DM)
Type 2 Diabetes
INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes
T2DM has become an American Epidemic. Currently 8% of the US population has diabetes and rates may be as high as 33% by the year 2050 (1).
- Trial name
- INSPIRE (NCT01087567)
- Testing
- Intensive insulin, Routine Care
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ohio University
Type 2 Diabetes Mellitus
Placebo Controlled, Dose Escalation Study in Subjects With Type 2 Diabetes Mellitus Being Treated With Sulfonylurea
The purpose of this study is to provide an initial assessment of the safety, tolerability and efficacy of ISIS 113715 in combination with sulfonylurea in type 2 diabetes subjects.
- Trial name
- NCT00455598
- Testing
- ISIS 113715
- Where
- 39 sites in Poland, Romania and 1 more
- Volunteers
- 88 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Vascular Function, Exercise Training
Evaluation of Effects of Exercise Training and ARB in DM Patients
The aims of this clinical trial are to assess the impacts on vascular function tests and circulating biomarkers of a short-term (12-week) low-to-median intensity exercise training or ARBs treatment in patients with DM and…
- Trial name
- NCT01053026
- Testing
- olmesartan
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital
Elderly Patients (>65 Years), Diabetes (DM)
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
The project aims to study the impact of SGLT2i therapy on clinical and biochemical aspects. in elderly. The project will combine different types of data, such as clinical and biological information, and will use advanced Bayesian…
- Conditions
- Elderly Patients (>65 Years), Diabetes (DM), Heart Disease, Renal Diseases
- Trial name
- NCT07119424
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Chiara Lanzani
Hypercholesterolemia
Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)
An efficacy and safety study of ezetimibe (+) simvastatin compared to atorvastatin at week 6 in diabetics or metabolic syndrome patients in Korea.
- Trial name
- NCT00157924
- Testing
- simvastatin (+) ezetimibe, atorvastatin
- Volunteers
- 190 people
- Sponsor
- Organon and Co
Type 2 Diabetes Mellitus
Cilostazol Versus Aspirin for Primary Prevention of Atherosclerotic Events
This multi-center, randomized controlled study aims to evaluate the efficacy of Cilostazol versus Aspirin for primary prevention of atherosclerotic events with Korean type 2 Diabetes Mellitus (DM) patients.
- Trial name
- CAPPA (NCT00886574)
- Testing
- Cilostazol, Aspirin
- Where
- 6 sites in South Korea
- Volunteers
- 400 people
- Sponsor
- Hanyang University
Diabetes
Comprehensive Intervention to Evaluate Outcomes AND Cost in Hospitalized Surgical Patients With Diabetes Mellitus (DM)
This study is being performed to evaluate whether a comprehensive discharge planning and close follow up for one year can improve clinical outcomes and cut costs of care for patients with poorly controlled diabetes.
- Trial name
- COACH-DM (NCT02065050)
- Testing
- team-based care
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in Japan
Primary Objective: To compare LixiLan to lixisenatide in glycated hemoglobin (HbA1c) change from baseline to Week 26 in patients with type 2 diabetes mellitus.
- Trial name
- LIXILAN JP-O1 (NCT02749890)
- Testing
- Insulin glargine/Lixisenatide (HOE901/AVE0010), Lixisenatide (AVE0010), Oral anti-diabetic drugs
- Where
- 61 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Sanofi
Dyslipidemia, Type 2 Diabetes Mellitus
Management of Dyslipidemia in Adult Type 2 Diabetes Patients in India
The purpose of study to assess the control of dyslipidemia in the Indian diabetic population treated with any hypolipidemic agent.
- Trial name
- SOLID (NCT01292018)
- Volunteers
- 5,400 people
- Sponsor
- AstraZeneca
Thyroid Function in DM
Thyroid Function Among Pediatric Patients With DM
Thyroid function among pediatric patients with type1 diabetes mellitus at the first presentation, from patients' characteristics to disease severity
- Trial name
- NCT05717933
- Testing
- thyroid hormones
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2 DM
Safety and Efficacy Assessment of Unani Formulation 'Dolabi' in Management of Diabetes Mellitus Type II
Diabetes is a chronic health condition that affects millions of people worldwide. In recent years, Pakistan has witnessed a significant increase in the prevalence of diabetes, making it a major public health concern.
- Trial name
- NCT06841497
- Testing
- Dolabi
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Hamdard University
Diabetes Mellitus, Type 2
Glufast On Insulin Glargine Trial in Type 2 DM
We will evaluate the efficacy and safety of combination therapy of 10 mg mitiglinide or 0.2mg voglibose with insulin glargine for 16 weeks after single administration of insulin glargine for 4 weeks in type 2 diabetic patients…
- Trial name
- GLORIA (NCT00663884)
- Testing
- Mitiglinide, Voglibose
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- JW Pharmaceutical
Type 1 Diabetes Mellitus
Type 1 Diabetes Mellitus Bone Mineral Density in Childhood and Adolescence
Type 1 Diabetes Mellitus is a disease that has an effect on bone mineral density. It is unclear how and when it effects the bone density.
- Trial name
- NCT01605149
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Creighton University
Diabetes Mellitus, Amputation Stumps
Phototherapy in DM Amputation Ulcers.
Diabetes mellitus is a major public health problem and it is estimated that 300 million individuals will be affected by the year 2030.
- Conditions
- Diabetes Mellitus, Amputation Stumps, Diabetic Foot
- Trial name
- NCT02883751
- Testing
- LED, Control group
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Dyslipidemia, Type 2 Diabetes Mellitus
Postprandial Fatty Acids and FABP2 in Type 2 Diabetes Mellitus (DM)
This study will be conducted in type 2 diabetic patient's to evaluate the if there is a different response of serum lipids after a standard meal (rich in saturated fatty acids) in patients who have the presence of a genetic…
- Trial name
- NCT00634673
- Testing
- sandwich
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 2 Diabetes Mellitus
Comparative Interventional Study to Evaluate the Role of LRYGBP, LSG & SMM
A Comparative Interventional Study to Evaluate the Role of Laparoscopic Roux-en-Y Gastric Bypass (LRYGBP), Laparoscopic Sleeve Gastrectomy (LSG) and Standard Medical Management (SMM) in Patients of Type II Diabetes Mellitus (DM)…
- Trial name
- NCT04058730
- Testing
- Laparoscopic Roux en Y Gastric by pass surgery, Laparoscopic Sleeve Surgery, Standard Medical Management
- Where
- 2 sites in India
- Volunteers
- 150 people
- Sponsor
- Max Institute of Minimally Access, Metabolic & Bariatric Surgery
Type 2 Diabetes Mellitus
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome
The purpose of this study is to determine whether an increase in lipid bodies in leukocytes will lead to an increase in eicosanoid production.
- Trial name
- NCT02498119
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diabetes Mellitus, Type 2, Diastolic Dysfunction
PDD in Type 2 Diabetes w/wo Diastolic Dysfunction
This study will advance the investigator's knowledge of the integrated cardiorenal and humoral physiology in type 2 diabetic patients with and without pre-clinical diastolic dysfunction, and test a novel therapeutic strategy…
- Trial name
- NCT03744975
- Testing
- LCZ 696
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Self-Care for Older People With Diabetes Mellitus
In Singapore, the prevalence of diabetes was approximately 12.8% in 2014 and was projected to rise to 22.7% in 2035. In 2015, the International Diabetes Federation (IDF) reported that Singapore has the second highest proportion…
- Trial name
- SCOPE-DM (NCT03890991)
- Testing
- SCOPE-DM, SCOPE-DM with 3 months' supply of glucometer, SCOPE-DM with 6 months' supply of glucometer
- Where
- Singapore
- Volunteers
- 320 people
- Sponsor
- National University of Singapore
Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (T2DM)
Improving the Activation Level of Diabetic Individuals
This study was planned to determine the activation levels of diabetic individuals and to improve the activation level. The study, planned as a descriptive and experimental type, is an attempt to increase the activation level of…
- Conditions
- Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (T2DM), Patient Activation, Diabetes Self-management
- Trial name
- NCT06973954
- Testing
- Text Message Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University