Clinical trials: Diabetes, Gestational
Gestational Diabetes
Active Patient GDM
Among women with GDM, the investigators will determine if a strategy of (1) a website-based information and motivational resource bank; (2) biosensor/ePlatform-based physical activity and GWG tracking; and/or (3) a health coach…
- Trial name
- NCT03802877
- Testing
- Resource bank, ePlatform, Health coach
- Where
- 6 sites in Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cardiovascular Diseases
Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary…
- Trial name
- HER-CROWN (NCT05632601)
- Testing
- PET scan
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Type I or Type II Diabetes (Excludes Gestational Diabetes)
Empowering Patients to Better Manage Diabetes Through Self-Care
This study will look at the impact of health insurance benefits on self management of diabetes for people with this condition. Studies have shown that when people with diabetes manage their disease better, they stay healthier.
- Trial name
- NCT00254501
- Testing
- Pharmacist Counseling, Educational materials
- Volunteers
- 69 people
- Sponsor
- Oregon State University
Gestational Diabetes Mellitus
Effect of Low Glycemic Index on Gestational Diabetes Mellitus
The purpose of this study is to determine whether glycemic index is effective in the treatment of maternal glycemia and pregnancy outcomes in women with Gestational Diabetes Mellitus.
- Trial name
- MyLGI (NCT03801824)
- Testing
- Standard Nutrition Therapy, Low Glycemic Index
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Universiti Putra Malaysia
Gestational Diabetes, Hyperglycemia
Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
One third of women with gestational diabetes (GDM), diabetes diagnosed during pregnancy, have abnormal glucose levels within 3 years after pregnancy, but follow up is low.
- Trial name
- ENGAGED (NCT06184373)
- Testing
- Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gestational Diabetes Mellitus
Islet Function in Gestational Diabetes
The purpose of this research is to understand how the function of the human pancreas changes during and after pregnancy.
- Trial name
- NCT07806695
- Testing
- Exendin 9-39
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
Insulin Resistance and Hypertensive Disorders in Pregnancy
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester.
- Trial name
- NCT00412230
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Messina
Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM)
Women With Previous GDM and the Effects of HIIT.
The goal of this clinical trial is to investigate if women with previous gestational diabetes (pGDM) are characterized with unique metabolic and molecular alterations compared to women without pGDM.
- Conditions
- Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM), High-intensity Interval Training
- Trial name
- GDM-HIIT (NCT07566845)
- Testing
- High-intensity interval training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Gestational Diabetes, Pregnancy Related
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes
The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM).
- Trial name
- START 1 (NCT06419777)
- Testing
- Insulin
- Where
- 2 sites in United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Gestational Diabetes
Soy Supplementation and Gestational Diabetes
The purpose of this study is to assess the feasibility of randomizing pregnant women at high risk for gestational diabetes to a 24-week period of soy food consumption.
- Trial name
- NCT02806739
- Testing
- Soy Group (Soy Protein + Isoflavones), Control Group (Minimize Soy Intake)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Gestational Diabetes Mellitus, Pregestational Diabetes Mellitus
Home Versus Hospital Care in Glucose Monitoring of Gestational Diabetes and Mild Gestational Hyperglycemia
Pregnancies complicated by diabetes and mild gestational hyperglycemia are associated with increased perinatal and maternal complications.
- Conditions
- Gestational Diabetes Mellitus, Pregestational Diabetes Mellitus, Mild Gestational Hyperglycemia
- Trial name
- NCT01441518
- Testing
- Home care, Hospital care
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gestational Diabetes
Glyburide vs Glucovance in the Treatment of GDM
A randomized comparison of glyburide to glucovance (metformin -glyburide) in the management of diabetes in pregnancy.
- Trial name
- GGIG (NCT02726490)
- Testing
- Glyburide, Glucovance
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Gestational Diabetes Mellitus
Glycemic Objectives of Women With Gestational Diabetes Mellitus
In a previous study, the investigators established the dosage of foetal glycated hemoglobin (FGH). It represents the mean of blood sugar 4-6 before the delivery.
- Trial name
- NCT02478762
- Testing
- Normal glycemic control, Low glycemic control
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Université de Sherbrooke
Gestational Diabetes Mellitus in Pregnancy
Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus.
Caring for women with gestational diabetes mellitus (GDM) is very time-consuming. Therapeutic strategy includes dietary and lifestyle measures and additional insulin therapy for 15 to 40% of the women with GDM if the glycemic…
- Trial name
- ACARB-GDM (NCT03380546)
- Testing
- Acarbose, Prandial insulin
- Where
- France
- Volunteers
- 341 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gestational Diabetes Mellitus in Pregnancy
The CGMS in GDM Labor and Delivery Study
Glucose control during labor is important for both fetus and mother. During labor and delivery, the goal is to maintain the sugars in the normal range as safely as possible as increased blood sugars 4-6 h prior to delivery leads…
- Trial name
- CGMSGDMLABOR (NCT05067075)
- Testing
- Blinded CGM
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Woman's
Gestational Diabetes, Pregnancy Complications
OneinSeven Gestational Diabetes Genetic and Socioeconomic Risk Study
The objective of the Gestational Diabetes Genetic Socioeconomic Risk Study is to generate genome wide association study data (GWAS) to calculate polygenic risk scores (PRS) for the development of gestational diabetes in pregnant…
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy Related, Genetic Predisposition
- Trial name
- NCT04789473
- Testing
- Polygenic Risk Score Generation
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Prenome
Respiratory Disorder in Patient With Gestational Diabetes
Respiratory Disorder During Sleep in the Pregnancy : A Risk Factor in Gestational Diabetese
Introduction: The pregnancy brings about physiological and hormonal modifications which cause sleep disorder. The sleeplessness, snoring and a bad sleepquality are frequent during the pregnancy.
- Trial name
- NCT02756442
- Testing
- Respiratory disorder assessment during sleep
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Gestational Diabetes Mellitus in Pregnancy
Comparison of Rice-richen and Wheaten-richen Meal on Glucose Control Among Chinese Women With Gestational Diabetes Melitus (GDM)
Since the prevalence of gestational diabetes melitus (GDM) increased by ..., as an important part of medical treatment, nutrition therapy is highly required to help patients achieve normoglycemia.
- Trial name
- NCT03550963
- Testing
- rice-richen meal, wheaten-richen meal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Prediabetic State, Obesity
Presessions for the National Diabetes Prevention Program
The National Diabetes Prevention Program (NDPP) is a widely available, evidence-based intervention that promotes weight loss to prevent type 2 diabetes; however, participant attendance is problematic and leads to suboptimal…
- Conditions
- Prediabetic State, Obesity, Gestational Diabetes
- Trial name
- NCT04022499
- Testing
- Presessions, National Diabetes Prevention Program
- Where
- United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority