Clinical trials: Diabetes, Gestational
Gestational Diabetes
An Exercise Intervention to Prevent Gestational Diabetes
Women diagnosed with gestational diabetes mellitus (GDM) are at substantially increased risk of developing type 2 diabetes and obesity, currently at epidemic rates in the United States.
- Trial name
- NCT00728377
- Testing
- Physical activity, Heath & Wellness
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Massachusetts, Amherst
Gestational Diabetes Mellitus
Structured Aerobic and Resistance Exercise and Gestational Diabetes
Gestational diabetes mellitus (GDM) is defined as impaired glucose tolerance of various degrees first manifested during pregnancy. The primary aim of treating GDM is to optimize glycaemic control and improve pregnancy outcomes.
- Trial name
- NCT02196571
- Testing
- Structured Exercise
- Where
- Croatia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Association for Functional Rehabilitation, Recreation and Applied Kinesiology Impulse
Gestational Diabetes, Myocardial Dysfunction
Fetal Myocardial Performance Index in Diabetic Pregnancies
The myocardial tissue is the most likely structure affected by hyperglycemia. The myocardial performance index (MPI) is a pulsed wave Doppler-derived index of global myocardial function.
- Trial name
- NCT03925064
- Testing
- myocardial performance index
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Gestational Diabetes Mellitus
The Effect of Oral Probiotics on Glycemic Control of Women With Gestational Diabetes Mellitus
Scientific background: Uncontrolled gestational diabetes mellitus (GDM) is associated with severe maternal and neonatal morbidities. Treatment of GDM is multidisciplinary and includes lifestyle changes and medications.
- Trial name
- NCT03864549
- Testing
- Femina II
- Where
- 4 sites in Israel
- Volunteers
- 93 people
- Sponsor
- HaEmek Medical Center, Israel
Gestational Diabetes Mellitus, Preeclampsia
User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study
Refine content and delivery of the mHealth delivered lifestyle intervention program through iterative testing with small groups of users who provide feedback through on-line asynchronous focus groups.
- Conditions
- Gestational Diabetes Mellitus, Preeclampsia, Gestational Hypertension, Pre-term Delivery
- Trial name
- NCT02384226
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Gestational Diabetes, Diabetes
The DNA Methylation of ARHGEF11 in Macrosomia
Background Macrosomia at birth is associated with subsequent susceptibility to obesity, abnormal glucose metabolism, hypertension and dyslipidaemia.
- Conditions
- Gestational Diabetes, Diabetes, Macrosomia, Fetal
- Trial name
- NCT03165643
- Testing
- OGTT
- Volunteers
- 239 people
- Sponsor
- Peking University First Hospital
Diabetes Mellitus
Texting for Diabetes
Diabetes is a common complication of pregnancy that increases risks for both the mother and baby. Poorly controlled diabetes has been associated with very large babies, congenital heart defects, stillbirth, birth trauma, and…
- Trial name
- NCT03025984
- Testing
- Texting
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- St. Louis University
Type 2 Diabetes
Nutraceutical Citrulline in Pregnancy
The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to pregnant women with type 2 diabetes will increase the plasma L-arginine/ADMA ratio, lower maternal blood…
- Trial name
- NCT02772887
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pittsburgh
Gestational Diabetes
Evaluation of Education for Gestational Diabetes
Prospective observational cohort study of women with gestational diabetes (GDM) based on the 'International Association of Pregnancy Study Groups' (IADPSG) criteria.
- Trial name
- NCT02528162
- Testing
- education
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gestational Diabetes Mellitus, Postpartum Depression
Gestational Diabetes and Perinatal Depression: an Intervention Program
Background: The gestational diabetes mellitus and perinatal depression are both global public health issues with high prevalence.
- Conditions
- Gestational Diabetes Mellitus, Postpartum Depression, Perinatal Depression
- Trial name
- NCT05800509
- Testing
- Clips Intervention, Structured Questionnaire Only
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gestational Diabetes Mellitus (GDM)
Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM)
The goal of this clinical trial is to determine whether the sequence of macronutrient consumption affects post-prandial glycaemia in women with gestational diabetes mellitus.
- Trial name
- DEFI-GDM (NCT06896799)
- Testing
- Visit 1: Protein/fat then carbohydrate. Visit 2: Carbohydrate then protein/fat., Visit 1: Carbohydrate then protein/fat. Visit 2: Protein/fat then carbohydrate.
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Queen's University, Belfast
Gestational Diabetes, Cardiovascular Risk Factors
Autonomic Nervous System and Exercise In Gestational Diabetes
The focus of this study is on individualized exercise prescription on primary prevention of cardiovascular diseases (CVD). Special attention is set on autonomic nervous system function and inflammation.
- Trial name
- ANS-EXE (NCT01675271)
- Testing
- individual exercise, general exercise
- Where
- Finland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Respiratory Viral Infections, Adverse Pregnancy Outcomes
APOs Associated With Respiratory Viral Infections Before and During Early Pregnancy
Adverse pregnancy outcomes (APOs) are a collection of conditions that have short-term and long-term effects of complications related to pregnancy and childbirth on pregnant women and their fetuses, including hypertensive…
- Trial name
- APO (NCT07257952)
- Volunteers
- 1,440 people
- Sponsor
- Shanghai General Hospital, China
Diabetes, Gestational
Effects of an Aquatic Physical Exercise Program on Glycaemic Control and Perinatal Outcomes of Gestational Diabetes: Study Protocol for a Randomized Controlled Trial
The purpose of this study is to verify the efficacy of an aquatic physical exercise program on GDM control and adverse maternal and fetal outcomes.
- Trial name
- NCT01940003
- Testing
- Aquatic exercise
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Gestational Diabetes
Evaluating the Efficacy of GPT-based Nutrition and Diabetic Counseling in Gestational Diabetes Management: A Randomized Controlled Trial (AIM-GDM)
The purpose of this study is to assess whether an AI based counseling service can be beneficial for patients to assist in management of gestational diabetes.
- Trial name
- AIM-GDM (NCT06582719)
- Testing
- GPT-based counseling, Nutritional Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Gestational Diabetes Mellitus in Pregnancy
Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes
This study aims to compare the maternal, fetal, and neonatal outcomes associated with the use of metformin versus glyburide for managing gestational diabetes.
- Trial name
- NCT06589141
- Testing
- MetFORMIN 500 Mg Oral Tablet, GlyBURIDE 2.5 MG Oral Tablet
- Volunteers
- 180 people
- Sponsor
- Assiut University
Gestational Diabetes Mellitus (GDM)
Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes Mellitus
Gestational diabetes mellitus(GDM) is a commom complication during pregnancy and associated with various adverse pregnancy outcomes for both the mother and her offspring.
- Trial name
- NCT03062475
- Testing
- lifestyle intervention with dietary and exercise recommendation
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Gestational Diabetes
The Use of the CPR to Predict Adverse Outcomes in GDM Pregnancies
The cerebro-placental ratio (CPR) is a tool for assessment of fetal wellbeing in the management of the growth restricted fetus. CPR is the ratio of the fetal middle cerebral artery pulsatility index (PI) to the umbilical artery…
- Trial name
- CPR GDM (NCT03072563)
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Unity Health Toronto
Gestational Diabetes Mellitus, Pregnancy
Gestational Diabetes Mellitus and Cardiovascular Disease: The Role of Vascular Dysfunction
The purpose of this research study is to look at whether there are differences in blood vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels, and levels of other blood markers between black…
- Trial name
- NCT00998712
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gestational Diabetes Mellitus, Pregnancy
GooDMoMS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics
This study includes a behavioral educational intervention that focuses on healthy eating and physical activity during pregnancy and the postpartum among women newly diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- NCT01600534
- Testing
- lifestyle counseling
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill