Clinical trials: Developmental Stuttering
Stuttering, Adult, Stuttering, Childhood
Transcranial Alternating Current Stimulation (tACS) in Stuttering
The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that…
- Conditions
- Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06740968
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Stuttering, Developmental Stuttering
Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering
This research is studying the use of low-intensity focused ultrasound (LIFU; a mild, noninvasive acoustic stimulation technique) in a small number of people to learn about its safety as a treatment for stuttering.
- Trial name
- NCT07668882
- Testing
- High DC LIFU
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Stuttering, Developmental, Aphasia, Primary Progressive
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life.
- Trial name
- NCT05437159
- Testing
- Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords
- Where
- 3 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stutter, Stuttering, Adult
Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering
The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.
- Conditions
- Stutter, Stuttering, Adult, Stuttering, Stuttering, Developmental
- Trial name
- NCT07180628
- Testing
- Speech Production During functional magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Stuttering, Stuttering, Childhood
The Development of Stuttering in Young Children
The goal of this longitudinal research is to learn why some children "grow out" of stuttering, while others persist. Children who do and do not stutter aged 3-6 years are eligible to participate in our study.
- Conditions
- Stuttering, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06578416
- Testing
- Standardized assessments of speech and language abilities
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Healthy Subjects, Stuttering, Developmental
Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Stuttering negatively impacts communication and reduces the overall quality of life and well-being of individuals who stutter. This study will provide a strong foundation for developing neural and behavioral interventions for…
- Trial name
- NCT06181149
- Testing
- Delaying speech initiation, Auditory errors and pre-speech auditory modulation, Contributions of the speech premotor cortex to pre-speech auditory modulation
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Persistent Developmental Stuttering
Explorative Study for Treating Persistent Developmental Stuttering With Ramipril
Persistent developmental stuttering (PDS) is diagnosed when developmental stuttering persists beyond adolescence. Most stutterers experience vast improvement in stuttering during childhood and it generally disappears within five…
- Trial name
- NCT04173949
- Testing
- Ramipril 2.5 MG
- Where
- 2 sites in Israel
- Volunteers
- 10 people
- Sponsor
- HaEmek Medical Center, Israel
Persistent Developmental Stutter, Childhood-Onset Fluency Disorder (Stuttering)
Stimulation of the Thalamus to Ameliorate Persistent Disfluency
Persistent developmental stutter / childhood onset fluency disorder is a disabling condition leading to significant communication and psychological disability.
- Trial name
- SToPeD (NCT05641701)
- Testing
- System On, System off
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Stuttering, Stuttering, Adult
Exploring the Nature, Assessment and Treatment of Stuttering
The purposes of this study are to 1) investigate potential speech, language, and psychosocial contributions to the experience of stuttering in monolingual and multilingual speakers, and to 2) evaluate interdisciplinary…
- Conditions
- Stuttering, Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT05908123
- Testing
- The Blank Center CARE Model(TM) for Individuals who Stutter
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Developmental Stuttering, Evoked Potentials Auditory
Effect of Stuttering Remediation Exercises on Cortical Auditory Evoked Potentials
studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
- Trial name
- NCT05473572
- Testing
- Fluency shaping exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alaa Mamdouh
Stuttering, Developmental
TreatPaCS = Treatment for Preschool Age Children Who Stutter
Treatment for preschool age children who stutter: a randomised, multicentre, non-inferiority parallel group pragmatic trial with Mini-KIDS, the social cognitive behaviour therapy and the Lidcombe Program with 249 children
- Trial name
- TreatPaCS (NCT05185726)
- Testing
- Lidcombe Program, Mini-KIDS, Social Cognitive Behavioural Therapy
- Where
- Belgium
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Thomas More University of Applied Sciences
Stuttering, Developmental
Investigating Non-invasive Brain Stimulation to Enhance Fluency in People Who Stutter
This study aims to test whether the application of transcranial direct current stimulation (tDCS) concurrent with fluency training results in improvements in speech fluency in adults with developmental stuttering, measured up to…
- Trial name
- INSTEP (NCT03335722)
- Testing
- Metronome-timed speech, Active tDCS
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Stuttering, Developmental
Non-invasive Brain Stimulation in Adults Who Stutter
Research studies in stuttering have shown that activity patterns in certain brain areas differ in people who stutter compared to people who do not stutter when speaking.
- Trial name
- NCT03437512
- Testing
- Anodal tDCS, Fluency training
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Stuttering/ Developmental
The Effect of the Non-invasive Brain Stimulation on the Speech Fluency Enhancement
The aim of this study is to determine the effectiveness of concurrent transcranial direct current stimulation (tDCS) and fluency training in adults with developmental stuttering.
- Trial name
- NCT03990168
- Testing
- Anodal tDCS, fluency intervention/ Delayed Auditory Feedback
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Iran University of Medical Sciences
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Developmental Stuttering
Effectiveness of Digital Manipulation of Thyroid Cartilage and Fluency Shaping Therapy for the Management of Stuttering in Adult
This study was conducted to determine the effectiveness of digital manipulation of thyroid cartilage for the management of stuttering in adult.There were three groups,Group A received Digital Manipulation of Thyroid cartilage…
- Trial name
- NCT03628755
- Testing
- Digital Manipulation of Thyroid cartilage, Fluency Shaping Therapy, combination Group
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Isra University
Developmental Articulation Disorder, Speech Disorder
Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life.
- Conditions
- Developmental Articulation Disorder, Speech Disorder, Stuttering
- Trial name
- NCT00001551
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Developmental Articulation Disorder, Stuttering
Study of Brain Activity During Speech Production and Speech Perception
The purpose of this study is to gain a better understanding of the brain's activity and organization in the development of speech disorders.
- Trial name
- NCT00004991
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Developmental Stuttering
Dopamine Function in Developmental Stuttering
This study will use positron emission tomography (PET) to examine the role of the chemical messenger dopamine in stuttering. It will measure and compare the number of dopamine receptors and the amount of dopamine released in the…
- Trial name
- NCT00024960
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)