Clinical trials: Development, Adolescent
Development, Child, Adolescent Behavior
Developmental Intervention for Infants of Adolescent Mothers
This is a randomized control trial to evaluate a simple language intervention curriculum that utilizes LENA recordings, linguistic feedback and text-message review of content to improve language environments and outcomes for…
- Conditions
- Development, Child, Adolescent Behavior, Language Development, Language Delay
- Trial name
- NCT03547492
- Testing
- Teaching Talking, LENA recordings-language, LENA recordings-motor
- Volunteers
- 108 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Autistic Disorder, Attention Deficit Disorder With Hyperactivity
Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to determine whether atomoxetine is effective in reducing ADHD (Attention Deficit/Hyperactivity Disorder) symptoms in children and adolescents with ASD (Autism Spectrum Disorder).
- Trial name
- NCT00380692
- Testing
- Atomoxetine
- Where
- 8 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Eli Lilly and Company
Intellectual Disability
Mental Health Crises in Youth With IDDs
This study is an unmatched, case-control study of 150 youth (Ages 7-17) with a parent reported Intellectual Developmental Disability (IDD) who present to Rady Children's Hospital Emergency Department with a Mental Health Crisis…
- Trial name
- NCT05471232
- Testing
- Genomic sequencing and molecular diagnostic results, if any., EHR-Based Network Model
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Tobacco Use Disorder, Smoking Cessation
Mobile Health (mHealth) Application for Smoking Cessation Among Adolescents in Indonesia
This mixed-methods study develops and evaluates a mobile health (mHealth) application for smoking cessation among Indonesian adolescents aged 13-15 years.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Adolescent Smoking
- Trial name
- NCT07198828
- Testing
- mHealth Smoking Cessation Application, Paper-based Control Materials
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Anxiety, Traumatic Stress
Personalizing Mental Health Treatment for Youth and Families
Incompatibility between evidence-based treatments (EBTs) and the cultural values, practices, and minoritized experiences of Latine youth and families contributes to racial-ethnic disparities in mental health treatment engagement…
- Conditions
- Anxiety, Traumatic Stress, Disruptive Behavior, Depression
- Trial name
- NCT07425366
- Testing
- Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT), Cultural Formulation Interview, Modular Approach to Therapy for Children
- Volunteers
- 64 people
- Sponsor
- University of Oregon
Heart Defects, Congenital, Executive Dysfunction
EF Intervention in Children With Severe Congenital Heart Disease
Survival rates of children with severe congenital heart disease (CHD) have increased with ongoing medical progress over the past decades.
- Trial name
- E-FIT (NCT05198583)
- Testing
- E-Fit
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital, Zurich
Autism Spectrum Disorder
Evaluation of Skillflix for Parents of Youth With ASD
The goal of this clinical trial is to evaluate the effectiveness of using a Microskills video training library for training parents of adolescents with ASD in talking with their teens about relationships and sexual health topics.
- Trial name
- NCT05958394
- Testing
- SkillFlix for Parents
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ashley Philliber
ASD, Autism Spectrum Disorder
The Effects of Tailored Judo Training and Nutritional Counseling on Physical Fitness and Body Composition in Children With Autism: A Study Including Blood Morphology and Genetic Analysis
The present research project aims to testing adapted judo training as a form of supportive developmental therapy, combined with nutritional counseling, to influence physical fitness, dietary habits, body composition, body…
- Conditions
- ASD, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Autism Spectrum
- Trial name
- AdaptedJudoASD (NCT07442994)
- Testing
- Adapted judo training for children and adeloscence with and without autism spectrum disorder - training in integrated groups
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Substance Use Disorders, Adolescent Behavior
The Canadian Underage Substance Use Prevention Trial
Despite having made some strides with respect to reducing adolescent drinking rates, illicit substance use and substance use disorders (SUDs) remain significantly above national targets for health promotion and disease prevention…
- Conditions
- Substance Use Disorders, Adolescent Behavior, Adolescent Development
- Trial name
- CUSP (NCT04198974)
- Testing
- PreVenture Training (PTtT), PreVenture Training+Implementation Facilitation
- Where
- 4 sites in Canada
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Gingivitis
A Person-centered, Theory-based, Intervention - Method Development Through the Integration of Digital Technology.
Studies have shown that Swedish adolescents have poor oral hygiene and with high prevalence of gingivitis. Therefore, more effective preventive programs in dental care are needed.
- Trial name
- NCT07306117
- Testing
- Person-centered, theory-based, intervention
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Vastra Gotaland Region
Autism Spectrum Disorder, Autism
In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve…
- Trial name
- NCT06577623
- Testing
- MINDful TIME
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children and Adolescents Aged From 7 to Less Than 18 Years Old With Autism Spectrum Disorder
The purpose of this study was to evaluate the efficacy and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715166
- Testing
- Bumetanide Oral Solution
- Where
- 45 sites in Brazil, France and 8 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
Scoliosis Idiopathic Adolescent
Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in ~10% of cases.
- Trial name
- NCT03539770
- Testing
- Posterior spinal fusion
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Mobile App-Based Intervention to Improve Toothbrushing in Children and Teens With Autism
The goal of this clinical trial is to test whether the autism-friendly app improves toothbrushing outcomes compared to a control app with only a digital mirror and countdown timer among children and teens (ages 8-17 years) with…
- Trial name
- BU (NCT07446413)
- Testing
- Brush Up App, Brush Down App
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Autism Spectrum Disorder
Treatment of Anxiety in Late Adolescents With Autism
Autism spectrum disorders (ASD) affect approximately 1.1% of late adolescents and young adults, making it one of the most common neurodevelopmental disorders.
- Trial name
- TALAA (NCT02977962)
- Testing
- Cognitive-Behavior Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Congenital Adrenal Hyperplasia
Androgen Reduction in Congenital Adrenal Hyperplasia
Children with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency tend to have elevated circulating levels of androgens, which can accelerate skeletal maturation and adversely impact adult height.
- Trial name
- ARCH (NCT03548246)
- Testing
- Abiraterone acetate, Hydrocortisone, Fludrocortisone
- Where
- 4 sites in United States
- Sponsor
- University of Texas Southwestern Medical Center
Adolescent Athletic Performance, Muscle Strength Development
Effects of Back Squat Exercise with or Without Blood Flow Restriction in Healthy Adolescent Basketball Athletes
The goal of this clinical trial is to assess the effectiveness of Blood Flow Restriction (BFR) training compared to traditional high-intensity training in adolescent basketball players aged 16-18.
- Conditions
- Adolescent Athletic Performance, Muscle Strength Development, Jump Height Improvement, Ground Reaction Force (GRF) Enhancement
- Trial name
- BFR (NCT06684093)
- Testing
- Back squat with Blood flow restriction machine, Back squats
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Adolescent Psychiatry, Antisocial Personality Disorders
Impaired Decision-making in Adolescents
There is clear evidence that aggressive behavior and disruptive behavior disorders (DBD) in middle childhood are associated with an increased risk for substance abuse in adolescence.
- Conditions
- Adolescent Psychiatry, Antisocial Personality Disorders, Substance-Related Disorders
- Trial name
- NCT01253993
- Where
- Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Adolescent - Emotional Problem, Agent
A Virtual Peer Agent for Counseling Adolescents With Stressful Life Events
This study aims to develop and evaluate a virtual companion agent for providing psychological support to adolescents who have recently experienced stressful life events. This is a single-arm, pre-post pilot trial.
- Conditions
- Adolescent - Emotional Problem, Agent, Psychological, Conversational
- Trial name
- NCT07305064
- Testing
- Virtual Peer Agent Counseling
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Sun Yat-sen University