Clinical trials: Detection of Helicobacter Pylori
Helicobacter Pylori Infection
New Strategy for the Detection and Treatment of Helicobacter Pylori Infections in Primary Care Guided by a Non-invasive PCR in Stool
In France, every year 1 million people are explored for Helicobacter pylori infection and 200,000 receive eradication treatment.
- Trial name
- HEPYPRIM (NCT05495854)
- Testing
- PCR test in the stool, Hp serology and gastroscopy
- Where
- 13 sites in France
- Volunteers
- 245 people
- Sponsor
- Poitiers University Hospital
Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Eradication Therapy of Helicobacter Pylori
Reinfection After Eradication of Helicobacter Pylori Infection
Helicobacter pylori is closely related with gastritis, peptic ulcer, gastric cancer and gastric MALT lymphoma, and it may participate in a variety of parenteral diseases.
- Conditions
- Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Eradication Therapy of Helicobacter Pylori, Detection of Helicobacter Pylori
- Trial name
- RAEHPI (NCT02674802)
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Helicobacter-associated Gastritis
Detection of Helicobacter Pylori Infection by High Resolution Endoscopy
Although endoscopic findings of H. pylori have been reported in the literature, there is still some debate over whether H. pylori-related gastritis can be diagnosed via endoscopic features alone.
- Trial name
- NCT01434992
- Where
- South Korea
- Volunteers
- 585 people
- Sponsor
- Kyunghee University Medical Center
Suspicion of Being Infected With H.Pylori
Show Equivalence of the Modified BreathID Compared to Currently Approved BreathID in H.Pylori Detection
The purpose of this study is to confirm equivalence of a new generation breath analyzer (Modified BreathID) in its ability to detect H. pylori compared to the currently approved BreathID® System.
- Trial name
- NCT01650831
- Testing
- Modified BreathID
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Meridian Bioscience, Inc.
Helicobacter Pylori Infection
The Prevalence of Family-unit Helicobacter Pylori Infection in Jiangsu
To assess Family-unit Helicobacter Pylori Infection rates and antimicrobial resistance rates in Jiangsu,China
- Trial name
- NCT05654857
- Testing
- PCR test in the stool
- Where
- 16 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Gastric Swab for Helicobacter Pylori Detection
A randomized controlled trial for comparing the Helicobacter pylori test using the swap method and the method using the conventional biopsy.
- Trial name
- NCT05349578
- Testing
- swab RUT
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Hospital
Helicobacter Pylori Infection
Comparison of Different Helicobacter Pylori Detection Methods in Patients With Chronic Atrophic Gastritis
As we know，Helicobacter pylori is closely related to many gastrointestinal diseases such as chronic gastritis, peptic ulcer disease,gastric carcinoma and gastric mucosa-associated lymphoid tissue lymphoma，as well as…
- Trial name
- NCT04923113
- Testing
- Histology，13C urea breath test，Stool antigen test，Serological antibody test for H.pylori and Serologic test with a current infection marker of H.pylori, Rabeprazole，Minocycline，Amoxicillin and Colloidal bismuth pectin
- Where
- 2 sites in China
- Volunteers
- 281 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastric Adenocarcinoma, Helicobacter Pylori
Prospective Gastric Cancer Screening Using Helicobacter Pylori High-Risk Single Nucleotide Polymorphism Detection
This is a prospective study designed to compare the performance of fecal H. pylori gastric cancer susceptibility analysis and the gastric cancer risk questionnaire for the early detection of gastric cancer.
- Trial name
- NCT06943781
- Testing
- Fecal Helicobacter pylori gastric cancer susceptibility gene test
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric Cancer
Pepsinogen II and Helicobacter Pylori Test in Gastric Cancer
The aim of this study to validate the role of pepsinogens in gastric cancer screening.
- Trial name
- NCT06301464
- Where
- South Korea
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gastritis
i-Scan for the Detection of Helicobacter Pylori
This study aims to assess whether iScan, an intra-endoscopic imaging technique is an accurate and reliable tool in detecting and characterising Helicobacter pylori (H pylori) and comparing this to standard endoscopic imaging with…
- Trial name
- NCT02385045
- Testing
- i-scan, narrow band imaging
- Where
- United Kingdom
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Helicobacter Pylori
Performances of a H. Pylori Stool PCR Test
Performance of a non-invasive test for the detection of Helicobacter pylori and its resistance to clarithromycin in stool by Real-Time PCR Amplidiag H. pylori + ClariR (Mobidiag).
- Trial name
- HEPYSTOOL (NCT03566004)
- Testing
- Stool specimen collection
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Poitiers University Hospital
Helicobacter Pylori
Development of a Laboratory Test for the Detection of a Fluorescent-labeled Urease Inhibitor Marker Attached to Helicobacter Pylori
The aim of this study is to compare the usual rapid urease test (RUT) to a new florescent-labeled urease inhibitor marker to diagnose Helicobacter Pylori.
- Trial name
- NCT04937426
- Testing
- Fluorescent-labeled Urease Inhibitor Marker to Detect Helicobacter Pylori
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hillel Yaffe Medical Center
Helicobacter Pylori Infection
Bag Mode BreathID Hp Validation Versus Endoscopy in Detection of Helicobacter Pylori
A new method of breath collection for testing for Helicobacter Pylori infection has been developed by Exalenz. In this study, it will be compared to the gold standard- endoscopy results to prove its accuracy.
- Trial name
- NCT02010112
- Testing
- Breath Test Collection bags
- Where
- 9 sites in United States
- Volunteers
- 193 people
- Sponsor
- Meridian Bioscience, Inc.
Helicobacter Pylori Infection, Helicobacter Pylori gyrA Levofloxacin Resistance Mutation
Helicobacter Pylori 23S rRNA/gyrA Gene Mutation Detection Kit (Fluorescence PCR Fusion Curve Method)
The purpose of this study was to evaluate the detection ability of Helicobacter pylori 23S rRNA/gyrA gene mutation detection kit (fluorescent PCR fusion curve method) for Helicobacter pylori gene mutation.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Pylori gyrA Levofloxacin Resistance Mutation, Fecal Drug Resistance Gene Detection, Helicobacter Pylori Infection, Susceptibility to
- Trial name
- NCT05410652
- Testing
- Detection of fecal samples with diagnostic kit, Sanger Sequencing group, Bacterial culture and drug sensitivity test of gastric mucosa samples
- Where
- 4 sites in China
- Volunteers
- 1,176 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
HELICOBACTER PYLORI INFECTIONS
Feasibility and Performance of FFPE qPCR for Detection of Clarithromycin Resistance in Helicobacter Pylori
This prospective observational study aims to evaluate the feasibility and performance of real-time PCR (qPCR) performed on formalin-fixed, paraffin-embedded (FFPE) gastric biopsies to detect Helicobacter pylori infection and…
- Trial name
- HED-2T (NCT07821294)
- Testing
- q-PCR on FFPE gastric biopsies
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Clinique Bizet
Helicobacter Pylori Infection Metabolic Dysfunction-Associated Fatty Liver Disease
Detection of Helicopacter Pylori in Patients With Metabolic Associated Fatty Liver Disease
Owing to the correlation between H.pylori and MAFLD, our study aims to search for H.pylori in every patient with MAFLD to aid in the management of MAFLD and improve quality of life for these patients by decreaseing morbidity and…
- Trial name
- HpyloriMAFLD (NCT07128147)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Molecular Detection of Antibiotic Resistance and H Pylori Eradication
H pylori eradication failure with recommended triple therapy is mainly related to antibiotic resistance. However,IN VITRO culture of H pylori is uneasy and is not performed in routine practice.
- Trial name
- HELICOSTIC (NCT01168063)
- Testing
- Molecular detection of antibiotic resistance, standard triple therapy (PPI, amoxicillin, clarithromycin, metronidazole)
- Where
- France
- Volunteers
- 1,386 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Helicobacter Pylori Infection
Dysplasia Detection and Helicobacter Pylori Eradication
The investigators in the present study, aimed to assess the efficacy of both White-Light Endoscopy with High Resolution Endoscopy-Narrow-band imaging in the diagnosis of Premalignant Gastric Conditions, before and after…
- Trial name
- NCT03917836
- Testing
- endoscopy and histology
- Where
- Italy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Helicobacter Pylori Infection
Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication
To investigate the efficacy, safety, and compliance of a simplified strategy using vonoprazan plus clarithromycin for first-line treatment in patients with Helicobacter pylori infection, among those infected with strains without…
- Trial name
- NCT07439445
- Testing
- Vonoprazan 20 mg twice daily + clarithromycin 500 mg twice daily for 14 days
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University First Hospital
Inflammatory Bowel Diseases
Detection of Helicobacter Pylori in Ulcerative Colitis Patients
Helicobacter pylori (H. pylori) infection is one of the most common infectious diseases in humans.
- Trial name
- NCT03172000
- Testing
- Colonoscopy and biopsy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University