Clinical trials: Dermatophyte Infection
Onychomycosis
Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail
The purpose of this study is to determine how much terbinafine is delivered to the nail bed after treatment with a number of modifications to a previously studied method for iontophoretic delivery of terbinafine gel.
- Trial name
- NCT01484145
- Testing
- Terbinafine HCl
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nitric BioTherapeutics, Inc
Dermatophytoses
Novel Electrolyzed Water Spray Treatment Mild Dermatophytosis
The purpose of this study is to test whether spraying the skin of patients of patients by use of the novel electrolyzed water spray will produce improvement in the condition of mild dermatophytosis.
- Trial name
- NCT05770245
- Testing
- The novel electrolyzed water spray
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Dove Medical Press Ltd
Onychomycosis
Efficacy and Safety Study of ME1111 in Patients With Onychomycosis
The purpose of the study is to determine the safety and efficacy of high and low strength of ME1111 solutions compared to the vehicle in the treatment of onychomycosis of the toenail.
- Trial name
- NCT02022215
- Testing
- ME1111 Solution, Low strength, ME1111 Solution, High strength, Matching Vehicle Solution
- Where
- 31 sites in United States
- Volunteers
- 304 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Onychomycosis
Fractional CO₂ Laser or 40% Urea With Topical Fluconazole Microemulsion in Onychomycosis
To evaluate the efficacy and safety of topical fluconazole microemulsion enhanced by fractional CO₂ laser versus by 40% urea ablation in treatment of Onychomycosis.
- Trial name
- NCT07033962
- Testing
- "Fractional CO2 laser" and "topical fluconazole microemulsion", "Urea 40%" and "topical fluconazole microemulsion"
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dermatophytosis
Combination of Oral Antifungal Treatment for Refractory Dermatophytosis
Superficial dermatophytosis is no longer a simple, cutaneous fungal infection that is easily amenable to treatment. It has evolved into a chronic and recurrent, difficult-to-treat condition, which affects the patients' physical…
- Trial name
- COATRD (NCT07816510)
- Testing
- Group A (TF group) receiving Oral Terbinafine (250 mg once daily) and Fluconazole (100 mg twice daily); 48 patients
- Where
- Bangladesh
- Volunteers
- 138 people
- Sponsor
- Chittagong Medical College
Tinea Pedis
Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis
To demonstrate comparable safety and efficacy of Taro Pharmaceuticals Inc. butenafine hydrochloride cream 1% (test product) and Lotrimin Ultra® cream (reference listed drug) in the treatment of interdigital tinea pedis, and to…
- Trial name
- NCT00835510
- Testing
- Butenafine cream 1% manufactured by Taro, Lotrimin Ultra (butenafine) 1%, Butenafine Vehicle manufactured by Taro
- Where
- 17 sites in United States, Belize
- Volunteers
- 548 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Tinea Capitis
Trichoscopic Predictors of Treatment Response in Tinea Capitis: A Prospective Study
Brief Summary (Plain Language Version) The goal of this observational study is to learn how well changes seen under a special microscope called a trichoscope (used to look at hair and scalp) match the success of treatment in…
- Trial name
- TCTREP (NCT07043582)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul Medeniyet University
Tinea Capitis
A Study Of Diflucan In Children With Ringworm Of The Scalp
The purpose of this study is to evaluate the safety and efficacy of fluconazole for the treatment of tinea capitis in pediatric patients aged 3 to 12 years.
- Trial name
- NCT00645242
- Testing
- fluconazole
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 185 people
- Sponsor
- Pfizer
Localized Skin Lesion, Mycosis Fungoides
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides
This phase II trial studies how well ultra low dose radiation therapy works in treating patients with mycosis fungoides. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
- Trial name
- NCT03398161
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- M.D. Anderson Cancer Center
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Prevalence of Onychomycosis, Diabetic Neuropathic Patients
Onychomycosis: Diagnosis and Prevalence in Diabetic Neuropathic Patients
The prevalence of onychomycosis among diabetic patients is still a debated question as well as the best way to diagnose the disease.
- Conditions
- Prevalence of Onychomycosis, Diabetic Neuropathic Patients, Diagnostic of Onychomycosis, Patients Clinically Suspected of Onychomycosis
- Trial name
- NCT00525187
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Vésale Hospital
Tinea Pedis
A Study Comparing the Efficacy of TA103 and the Placebo Control in the Treatment of Interdigital Tinea Pedis.
To evaluate and compare the safety and efficacy of TA103 in the treatment of tinea pedis.
- Trial name
- NCT04883593
- Testing
- TA103
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Tinea Pedis
Clinical Study to Evaluate the Therapeutic Equivalence of Ketoconazole Cream 2% in the Treatment of Tinea Pedis
Clinical Study to Evaluate the Therapeutic Equivalence of Ketoconazole Cream 2% in the Treatment of Tinea Pedis
- Trial name
- NCT03824912
- Testing
- Ketoconazole Cream 2%, Ketoconazole Cream 2% (G&W Laboratories Inc.)
- Where
- 9 sites in United States, Belize and 1 more
- Volunteers
- 831 people
- Sponsor
- Encube Ethicals Pvt. Ltd.
Infected Toenails, Onychomycosis
PinPointe FootLaser for the Treatment of Onychomycosis
To evaluate the safety and efficacy of the PathoLase FootLaser treatment of infected toenails.
- Trial name
- NCT00935649
- Testing
- PinPointe FootLaser
- Where
- 4 sites in United States, Canada
- Volunteers
- 134 people
- Sponsor
- PathoLase, Inc.
Tinea Pedis
Evaluate the Safety and Efficacy of Naftifine Hydrochloride Cream 2% and Naftin® Cream 2% in Patients With Tinea Pedis
The objective of this study is to compare the efficacy and safety of the test formulation of Naftifine Hydrochloride Cream 2% to Naftin® (Naftifine Hydrochloride) 2% Cream in a 6 week study in patients with tinea pedis.
- Trial name
- NCT02132260
- Testing
- Naftifine Hydrochloride Cream 2%, Naftin® (Naftifine Hydrochloride) Cream 2%
- Volunteers
- 890 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Tinea Pedis
Evaluate the Clinical Equivalence of Two Naftifine HCl 1% Creams in Patients With Interdigital Tinea Pedis
The objective of this study is to evaluate the efficacy and safety of the test formulation of Naftifine HCl Cream 1% (Taro Pharmaceuticals Inc.) as compared to the already marketed formulation Naftin® (Naftifine HCl) 1% Cream…
- Trial name
- NCT01580891
- Testing
- Naftifine HCl Cream 1%, Naftin® (Naftifine HCl) Cream 1%
- Volunteers
- 1,053 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Ankle Inversion Sprain, Chronic Instability of Joint
Effectiveness of Balance Training and Dynamic Neuromuscular Stabilization Training in Amateur Athletes with Chronic Ankle Instability
The goal of this clinical trial is to determine and compare the effects of balance and dynamic neuromuscular stabilization training on ankle function ability, functional instability severity, physical activity level, muscle…
- Conditions
- Ankle Inversion Sprain, Chronic Instability of Joint, Chronic Pain, Athlete Foot
- Trial name
- NCT06296537
- Testing
- Dynamic Neuromuscular Stabilization Training (DNS), Balance Training, Conventional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Medipol University
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Onychomycosis, Chronic Paronychia
A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment
This study was designed to demonstrate the efficacy of this product in non-dermatophyte (Scytalidium dimidiatum) onychomycosis and chronic paronychia treatment in Thai patients.
- Trial name
- NCT02464826
- Testing
- Nailprotex
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Invasive Fungal Infections, Invasive Aspergillosis
Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients
The main objective of this study is to test prospectively the performance of an algorithm stratified by an index based on neutrophil counts in association with galactomannan assay and image tests to start an antifungal early…
- Conditions
- Invasive Fungal Infections, Invasive Aspergillosis, Invasive Fusariosis
- Trial name
- Dindexval (NCT00982540)
- Testing
- caspofungin as preemptive antifungal therapy
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal do Rio de Janeiro