Clinical trials: Dermatologic Complication
Advanced Malignant Neoplasm, Dermatologic Complication
Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab
This randomized phase II trial studies how well giving spironolactone works in preventing rash in patients with cancer that has spread to other places in the body and are receiving panitumumab and cetuximab.
- Trial name
- NCT01867294
- Testing
- Doxycycline, Management of Therapy Complications, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Academic and Community Cancer Research United
Edema, Dermatologic Complication
Care Bundle for Prevention of Skin Complications and Edema in Restrained Patients
Physical restraint (restraint) is defined as the restriction of a patient's free body movements and the prevention of the patient's ability to move easily by healthcare professionals using physical or mechanical devices to…
- Conditions
- Edema, Dermatologic Complication, Physical Restraints
- Trial name
- SCER-ICU (NCT07442344)
- Testing
- Evulation, Application of physical restraint material, Elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Kocaeli City Hospital
Dermatologic Complications, Palmar-plantar Erythrodysesthesia
Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer
RATIONALE: Pyridoxine may help prevent hand-foot syndrome caused by capecitabine in patients with cancer. It is not yet known whether pyridoxine is more effective than a placebo in preventing hand-foot syndrome in patients with…
- Conditions
- Dermatologic Complications, Palmar-plantar Erythrodysesthesia, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00486213
- Testing
- pyridoxine hydrochloride
- Where
- Singapore
- Volunteers
- 210 people
- Sponsor
- National Cancer Centre, Singapore
Colorectal Cancer, Dermatologic Complications
S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride
RATIONALE: Questionnaires that patients can use to assess skin toxicities related to treatment may help identify the intermediate-and long-term effects of cetuximab, panitumumab, or erlotinib hydrochloride.
- Conditions
- Colorectal Cancer, Dermatologic Complications, Lung Cancer, Therapy-related Toxicity
- Trial name
- NCT01416688
- Testing
- assessment of therapy complications, psychosocial assessment and care, quality-of-life assessment
- Where
- 113 sites in United States
- Volunteers
- 146 people
- Sponsor
- SWOG Cancer Research Network
Surgical Site Infection
Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery
The purpose of the study is to assess the effectiveness of a single dose of preoperative antibiotic in reducing surgical site infections in certain dermatological procedures.
- Trial name
- NCT04580472
- Testing
- Cephalexin
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- Carilion Clinic
Type 1 Diabetes, Dermatologic Complication
Prevention of Skin Problems With Diabetes Devices in Pediatric Patients
A Cluster-controlled Intervention Trial regarding Prevention of Dermatological Complications towards use of Continuous glucose monitoring and insulin pumps in pediatric patients with Type 1 Diabetes.
- Trial name
- NCT04258904
- Testing
- Skin Care Program
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Copenhagen University Hospital at Herlev
Surgical Site Infection, Patient Satisfaction
Effect of Surgical Site Infections on Patient Reported Cosmetic Outcomes in Dermatologic Surgery
This study involves surveying two matched groups of patients that underwent dermatologic surgery at our department. One group had a documented surgical site infection and the other didn't.
- Trial name
- NCT04744961
- Testing
- SCAR-Q survey
- Where
- Sweden
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Region Skane
Dermatologic Disease, Onychomycosis of Toenail
Photodynamic Therapy and Topical Antifungal for Onychomycosis in Patients With Diabetes.
There are different therapeutic alternatives for onychomycosis. Systemic therapy is widely used due to its easy accessibility, low cost and high efficacy, but may be associated with systemic adverse events and drug-drug…
- Conditions
- Dermatologic Disease, Onychomycosis of Toenail, Diabetic Foot, Diabetes Mellitus
- Trial name
- NCT06485050
- Testing
- Photodynamic therapy
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Dermatologic Complications
Preliminary Study of Peel Force and Discomfort of Removal of Adhesive Barriers in Normal and Peristomal Skin
This purpose of this study is to look at three commercially available ostomy barriers on peristomal (around the stoma) skin. Repeated barrier application and removal over years causes changes to the skin that the investigators…
- Trial name
- NCT02003404
- Testing
- Control Abdominal Skin, Peristomal Abdominal Skin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hollister Incorporated
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Dermatologic Complications, Malignant Neoplasm
Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab
This clinical trial studies menadione topical lotion in treating skin discomfort and psychological distress in patients with cancer receiving panitumumab, erlotinib hydrochloride, or cetuximab.
- Conditions
- Dermatologic Complications, Malignant Neoplasm, Pain
- Trial name
- NCT01393821
- Testing
- menadione topical lotion, questionnaire administration, management of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Local Anaesthetic Complication, Pain
Kinetic Anesthesia Device Study
Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices (KAD) have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, though no studies of lidocaine…
- Trial name
- NCT03344510
- Testing
- Kinetic Anesthesia Device, Control
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Acanthosis Nigricans, Polycystic Ovary Syndrome
Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
OBJECTIVES: I. Evaluate insulin resistance in thin and obese hyperandrogenic women with polycystic ovarian disease or hyperandrogenism insulin resistance acanthosis nigricans syndrome and in thin and obese controls, using an…
- Trial name
- NCT00004311
- Testing
- leuprolide acetate, spironolactone
- Sponsor
- National Center for Research Resources (NCRR)
Surgical Wound Infection
Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries
Patients are often counseled to keep a surgical wound dry for 2 to 3 days. The rationale is likely to decrease the risk of infection and bleeding. However, this has never been formally studied.
- Trial name
- NCT01773694
- Testing
- Early Water Exposure
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- Milton S. Hershey Medical Center
Long Covid-19
LOng COvid COmorbidities: Endocrine,Metabolic,Neuropsychiatric,Muscle,Cardiovascular,Pulmonary,Dermatologic Dysfunctions
Considering the compelling amount of studies focused on patients in the active phase of COVID-19 disease and the scarcity of studies focused on patient cured from disease aimed at evaluating the sequelae of SARS-CoV-2 infection…
- Trial name
- LO-COCO (NCT05293366)
- Testing
- Assessments of endocrinological phenotypes of LO-COCO patients, Assessment of muscular phenotypes of LO-COCO patients, Assessment of neuropsychiatric phenotypes of LO-COCO patients
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT03848962
- Where
- 2 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Dermatologic Complications, Pain
Scrambler Therapy in Treating Chronic Pain in Patients With Rash From Varicella Zoster Virus Infection
This pilot clinical trial studies how well scrambler therapy works treating chronic pain in patients with rash from varicella zoster virus infection.
- Conditions
- Dermatologic Complications, Pain, Viral Infection
- Trial name
- NCT01347736
- Testing
- scrambler therapy, questionnaire administration, dermatologic complications management/prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Biotherapy, Chronic Inflammatory Disease
Skin Adverse Reactions Occuring in Children Treated by Biotherapy for Chronic Inflammatory Disease
Biological treatments (BT) are commonly prescribed to treat chronic inflammatory diseases in children. Paradoxical reactions during treatment with a biological agent can be defined as the appearance or exacerbation of a…
- Conditions
- Biotherapy, Chronic Inflammatory Disease, Allergic Skin Reaction, Pediatric Disorder
- Trial name
- MDEBMIC (NCT04327752)
- Testing
- dermatological consultation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Healthy, Lupus
Direct to Patient Minimal Risk Biospecimen and Data Collection Research
This study aims to help researchers better understand health conditions and develop improved tests, treatments, and cures for diseases.
- Conditions
- Healthy, Lupus, Celiac, Kidney Disease
- Trial name
- JBMR (NCT07128966)
- Testing
- Observation
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Joined Bio
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT05080907
- Testing
- Observational
- Where
- 7 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc