Clinical trials: Depressive Disorders
Perinatal Depression
Responsive e-Health Intervention for Perinatal Depression in Healthcare Settings
Perinatal depression is experienced by at least 14-20% of pregnant and postpartum women, and is recognized as the most common complication of childbirth.
- Trial name
- MMB (NCT03995316)
- Testing
- Treatment As Usual + MMB 2.0, Treatment As Usual Only
- Where
- 2 sites in United States
- Volunteers
- 191 people
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Depression
Accelerated Transcranial Magnetic Stimulation (aTBS) to Treat Depression
The primary aims of this study are to investigate the efficacy of L DLPFC accelerated TMS (aTMS) in patients with depression in Singapore and to assess the whether a 1-week course of treatment is as effective as a 4-week course…
- Trial name
- NCT03941106
- Testing
- Accelerated repetitive transcranial magnetic stimulation
- Where
- 2 sites in Singapore
- Volunteers
- 38 people
- Sponsor
- Institute of Mental Health, Singapore
Major Depressive Disorder
Changes in Cerebral Glucose Metabolism After Electroconvulsive Therapy (ECT)
There exist already a few studies that have measured changes of brain metabolism pre and post Electroconvulsive Therapy (ECT) by Positron emission tomography (PET) but these were all performed in a small number of patients and…
- Trial name
- NCT01514435
- Testing
- Electroconvulsive therapy, 18-Fluoro-desoxy-glucose positron emission tomography
- Where
- Austria
- Volunteers
- 13 people
- Sponsor
- Medical University of Graz
Parkinson's Disease, Depression
Magnetic Stimulation for Parkinson Disease
During transcranial magnetic stimulation (TMS), a magnetic coil is placed on the front part of the head. Electric current passes through the coil in brief pulses.
- Trial name
- NCT00029276
- Testing
- Prefrontal transcranial magnetic brain stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Major Depressive Disorder
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression
Major depressive disorder (MDD) is a prevalent and disabling mental health condition. A recent meta-analysis shows that across all forms of psychotherapy, only 43% of all depressive patients fully recover from MDD and relapse…
- Trial name
- VR-Moodboost (NCT05486676)
- Testing
- VR-Moodboost; a Virtual Reality intervention for depression to enhance positive affect and reduce depressive symptoms.
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Claudi Bockting
Overweight, Glucose Metabolism Disorders
The Physical Activity and Nutrition in Children (PANIC) Study
The Physical Activity and Nutrition in Children (PANIC) Study is a single-centre controlled trial on the effects of a combined physical activity and dietary intervention on cardiometabolic risk factors and other health outcomes…
- Conditions
- Overweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood Pressure
- Trial name
- PANIC (NCT01803776)
- Testing
- lifestyle counseling
- Where
- Finland
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Major Depressive Disorder
Comparison of Tianeptine Versus Escitalopram Patients Major Depressive Disorder
The primary object of this study is to confirm the superiority of tianeptine compared to escitalopram on effects that improves subjective and objective cognitive impairments in patients suffering from major depressive disorder.
- Trial name
- CAMPION (NCT01309776)
- Testing
- Tianeptine, Escitalopram
- Where
- 6 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Samsung Medical Center
Mental Health, Anxiety
RCT for Latina Mental Health Using Web-Based Apps
This study compares a choice-driven, interactive, evidence-informed storytelling web-based app intervention with links to resources and treatment (Tx) recommendations (made by a character via her blog) and Tx locator, to a…
- Conditions
- Mental Health, Anxiety, Depression, Well-Being, Psychological
- Trial name
- NCT06874790
- Testing
- Catalina, Control webpage
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Epilepsy
Epilepsy and Mood Regulation Disorder in Children
Epilepsy is a multifaceted disorder and a major public health problem. In addition to recurrent and unpredictable seizures, abnormalities in psychiatric status, cognition and social-adaptive behaviors are potential major sources…
- Trial name
- EPILETRE (NCT02568813)
- Testing
- Multiscore Depression Inventory for Children scale
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Spinal Cord Injuries, Depression
Telepsychology in Spinal Cord Injury
This study will determine the effectiveness of tele-psychology in treating persons with spinal cord injury (SCI) with depressed mood in the early period post-rehabilitation discharge.
- Trial name
- NCT03711760
- Testing
- telepsychology
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Santa Clara Valley Health & Hospital System
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Depression Disorders
Efficacy and Safety of tACS for Depression: a Multicenter RCT Study
Transcranial alternating current stimulation (tACS) is a promising non-invasive technique for major depression, because of its advantage of lower risks and expenses compared to other therapies such as deep brain stimulation…
- Trial name
- NCT06891326
- Testing
- active tACS
- Where
- 2 sites in China
- Volunteers
- 72 people
- Sponsor
- Ruijin Hospital
Transcranial Direct Current Stimulation, Major Depressive Disorder
tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder
Study of tDCS intervention on motivational anhedonia of Major Depressive Disorder
- Conditions
- Transcranial Direct Current Stimulation, Major Depressive Disorder, Event-Related Potentials
- Trial name
- NCT04425278
- Testing
- transcranial direct current stimulation with real current
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Major Depressive Disorder, Borderline Personality Disorder
Triage Survey for Psychiatry Research Eligibility
TRIAGE-Psych is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored psychiatry clinical trials.
- Conditions
- Major Depressive Disorder, Borderline Personality Disorder, Generalized Anxiety Disorder
- Trial name
- TRIAGE-Psych (NCT05800925)
- Testing
- Survey
- Where
- 6 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Adams Clinical
Covid19, Depression
Depression and Anxiety in Long Term Coronavirus Disease COVID-19
Background : Depression and Anxiety are linked to COVID (Coronavirus Disease)-19 long-term impact through several mechanisms. The possible way is the alteration of neurotransmitter regulation from the interaction of severe acute…
- Conditions
- Covid19, Depression, Anxiety
- Trial name
- DALT-COV (NCT04893668)
- Testing
- Depression, Anxiety
- Where
- Indonesia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Maternal Distress, Prenatal Stress
Laughter Yoga's Impact on Traumatic Childbirth Preparation
This study will be conducted as a single-center, parallel-group, randomized controlled intervention trial to determine the effects of birth preparation training supported by laughter yoga on the perception of traumatic birth…
- Conditions
- Maternal Distress, Prenatal Stress, Pregnancy Related
- Trial name
- NCT06663397
- Testing
- Laughter Yoga, Standard Childbirth Preparation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stress, Depression
Evaluation of the Efficacy and Mechanisms of Change of Compassion Cultivation Training in Medical Students
The aim of this randomized, waitlist controlled trial is to examine the efficacy of the Compassion Cultivation Training (CCT©) in reducing psychological distress (i.e., stress, anxiety and depression) and burnout symptoms while…
- Conditions
- Stress, Depression, Anxiety, Burn Out
- Trial name
- NCT04690452
- Testing
- Compassion Cultivation Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depression
Efficacy of Blue Light Treatment in Patients With Nonseasonal Major Depressive Disorder
To compare the efficacy of blue light, bright light and dim light in the treatment of with nonseasonal major depression disorder(MDD) in adults.
- Trial name
- NCT04555408
- Testing
- blue light, bright light, dim light
- Volunteers
- 162 people
- Sponsor
- Shanghai Zhongshan Hospital
Depressive Disorder, Major, Suicide
Rapid Acting TMS for Suicide Ideation in Depression
This study evaluates the effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), on the neural networks underlying explicit and implicit suicidal cognition…
- Trial name
- NCT05100004
- Testing
- Accelerated Theta Burst Stimulation
- Where
- United States
- Sponsor
- Stanford University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.