Clinical trials: Dependence Addictive
Alcoholism
Oxytocin in Alcohol Use Disorder
Background: Oxytocin is a naturally occurring substance in the body. Studies show that oxytocin may affect how the body responds to alcohol. Researchers believe oxytocin may be a possible treatment for alcoholism.
- Trial name
- NCT02711189
- Testing
- Oxytocin
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Technology Addiction, Musculoskeletal System
Relationship Between Academic Achievement, Musculoskeletal System, Quality of Life and Technology Addiction
The increasing use of technological devices such as mobile phones and computers has become indispensable elements of daily life.
- Conditions
- Technology Addiction, Musculoskeletal System, Quality of Life, Youth
- Trial name
- NCT04790721
- Where
- Turkey (Türkiye)
- Volunteers
- 473 people
- Sponsor
- Pamukkale University
Non-Small Cell Lung Cancer
Exercise in Extended Oncogene Addicted Lung Cancer in Active Treatment
This is an interventional, non-pharmacologic, randomized controlled study evaluating the impact on quality of life of a personalized exercise program in oncogene addicted lung cancer patients undergoing active treatment.
- Trial name
- EXcellenT (NCT05306652)
- Testing
- Supervised physical activity, Unsupervised physical activity
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- AUSL Romagna Rimini
Focus: Effects of Nicotine and Alcohol on Brain Circuits
Neural Mechanisms Underlying Nicotine and Alcohol Combinations
Nicotine and alcohol are frequently used together and their combined use contributes to more than half a million deaths each year, with more alcoholics dying from smoking-related diseases than from alcohol-related diseases.
- Trial name
- QfMRI (NCT02049268)
- Testing
- Nicotine + Alcohol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Internet Gaming Disorder
The Effect of Repetitive Transcranial Magnetic Stimulation for Internet Gaming Disorder
This study aims to investigate the intervention effects of navigated repetitive transcranial magnetic stimulation (rTMS) on craving regulation in individuals with internet gaming disorder (IGD).
- Trial name
- NCT06634498
- Testing
- real rTMS on the dlPFC
- Where
- 2 sites in China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jin-tao Zhang
Alcohol Abuse, Alcohol Addiction
Guided and Unguided Internet Treatment for Problematic Alcohol Use
The purpose of this study was to determine whether a 10-week internet-based program based on cognitive behavioral therapy (CBT) is effective in the treatment of alcohol problems, and if having therapist guidance leads to greater…
- Trial name
- NCT02384304
- Testing
- Choice, Messages, Self help
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Opiate Dependence
Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From Jail
This pilot study's primary aim is to compare rates of sustained opioid relapse, defined as self-reported opioid use >50% (>15 of 30) of days during the first 30 days following release from jail, among persons treated with XR-NTX…
- Trial name
- NCT01180647
- Testing
- Extended-Release Naltrexone, Motivational Enhancement Counseling
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Chronic Neck Pain, Exercise Addiction
Effect of Cervical Stabilization and Oculomotor Exercises on Position Sense With Chronic Neck Pain
The aim of this study is to compare the effectiveness of Cervical Stabilization and Oculomotor Exercises in addition to the classical physiotherapy on pain severity, cervical joint position sense, posture, cervical joint range of…
- Trial name
- NCT05083858
- Testing
- Classical Physiotherapy Program + Cervical Stabilization Exercises, Classical Physiotherapy Program + Oculomotor Exercises, Classical Physiotherapy Program
- Where
- Cyprus
- Volunteers
- 72 people
- Sponsor
- Eastern Mediterranean University
Alcohol-Related Disorders, Alcoholism
Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction
This clinical study is being conducted to compare the effectiveness of two psychological treatments for alcohol addiction: Combined Behavioral Intervention (CBI) and Ericksonian Hypnotherapy (EH).
- Conditions
- Alcohol-Related Disorders, Alcoholism, Substance-related Disorders
- Trial name
- NCT06916754
- Testing
- Combined Behavioral Intervention, Ericksonian Hypnotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Beykoz University
Methamphetamine Dependence, Treatment Seeking
A Clinical Trial of Acamprosate for Treatment of Methamphetamine Addiction
This clinical trial will compare 10 week treatment with acamprosate (2 gr/day) versus placebo, combined with weekly abstinence oriented individual counseling, in methamphetamine dependent patients, 72 subjects will be enrolled…
- Trial name
- AcampMet (NCT00571922)
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Sleep Disorder
Targeted Intervention on Sleep Disorders During Tobacco or Cannabis Cessation Therapy
During a cessation therapy for tobacco or cannabis, sleep disorders are one of the main risk factors of relapse, and a symptom of substance withdrawing.
- Trial name
- ISAC (NCT07202351)
- Testing
- Screening and management of sleep disorders
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier St Anne
Social Media Addiction
Effect Of Social Media On Body Weight And Eating Behaviour In Housewife Versus Worker Postmenopausal Women
The purpose of this study is to determine the effect of social media on body weight and eating behaviour in housewife versus worker postmenopausal women.
- Trial name
- NCT06612905
- Testing
- Detection of the time spent on social media, Evaluation of body composition and basal metabolic rate, Evaluation of eating behavior among social media users
- Where
- Egypt
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nomofobia, Body Image Disturbance
Relationships Between Nomophobia Levels and Perceived Stress, Body Image and Food Addiction Among University Students
The purpose of this study is to examine the effects of nomophobia levels on stress, food addiction, and body image among undergraduate students aged 18-30 at Bahçeşehir University, Faculty of Health Sciences.
- Conditions
- Nomofobia, Body Image Disturbance, Body Image, Body Image Disorder
- Trial name
- NCT07518056
- Testing
- Questionnaires on Nomophobia, Perceived Stress, Body Image, and Food Addiction; Body Composition and Anthropometric Measurements via Bioelectrical Impedance Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bahçeşehir University
Cocaine Related Disorders
Contingency Management Treatment for Crack Addiction - Study With Brazilian Population
Crack addiction has become a severe health problem in Brazil. Today, crack addiction is the primary cause for inpatient treatment for all illicit substances.
- Trial name
- NCT01815645
- Testing
- ST+CM, standard treatment
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Federal University of São Paulo
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Opioid Use Disorder
Following Outcomes Remotely Within Addiction Recovery Domains
The aim of this study is to describe outcome of people with opioid use disorder over the long-term by collecting monthly and yearly data on their recovery.
- Trial name
- FORWARD (NCT06001437)
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Mclean Hospital
Opioid Related Disorders, Opiate Addiction
Monitoring Patterns of Prescribing to Identify Changes in Access to ER/LA Opioid Analgesics
Changes in prescribing will be compared in prescribers from specialties whose prescribing is hypothesized to be relatively unaffected by the REMS (such as oncologists and hospice providers) versus those for whom the REMS could…
- Conditions
- Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02920775
- Testing
- Non-interventional study - retrospective database review
- Volunteers
- 360,000 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Nicotine Dependence
Adaptive Pharmacotherapy for Smoking Cessation
The purpose of this study is to assess an "adaptive" approach to smoking cessation pharmacotherapy. The protocol is designed to compare adaptive vs.
- Trial name
- NCT02501265
- Testing
- Varenicline Standard Protocol, Nicotine Patch Standard Protocol, Varenicline Adaptive Protocol
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Duke University
Substance Abuse Disorder, Addiction
Cross-sectional Functional Stratification Based on Psychometric Profiling and Machine Learning in Patients With Substance Use Disorders (SUD)
Substance use disorders (SUDs) show considerable clinical heterogeneity that limits the usefulness of traditional categorical diagnoses.
- Conditions
- Substance Abuse Disorder, Addiction, Clinical Stratification, Substance-related Disorders
- Trial name
- SISAP-TUS (NCT07590154)
- Testing
- No intervention (observational only)
- Where
- Mexico
- Volunteers
- 155 people
- Sponsor
- Lauro Gutiérrez Castro
Opioid-use Disorder, Opioid-related Disorders
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
The RECOVER Study will examine clinical, environmental and socioeconomic factors in recovery from opioid use disorder (OUD) over a 24-month period following exit from a Phase III clinical program for a buprenorphine…
- Trial name
- RECOVER® (NCT03604861)
- Testing
- Not applicable - no defined intervention
- Where
- 35 sites in United States
- Volunteers
- 534 people
- Sponsor
- Indivior Inc.