Clinical trials: Dentofacial Deformities
Dentofacial Deformities
Stability of Two Designs of Patient Specific Osteosynthesis For Fixation of LeFort 1 Osteotomy in Orthognathic Surgery
A comparison of the stability of two different designs of patient specific fixation devices for the performance of splintless computer guided le fort 1 osteotomy in orthognathic surgery workflow for the correction of a variety of…
- Trial name
- NCT05522348
- Testing
- Stability of a two piece PSI deign in splintless maxillary orthognathic surgery, Stability of a one piece PSI deign in splintless maxillary orthognathic surgery
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentofacial Deformity
Lower Laser Therapy in Orthognathics Surgery
This study will examine the use of lower laser therapy to reduce edema and pain in orthognathics surgery.
- Trial name
- NCT01530100
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentofacial Deformities
Custom Titanium Plates vs. 3D Splints in LeFort I Osteotomy
This randomized comparative study evaluates the accuracy and feasibility of two techniques for maxillary repositioning in Le Fort I osteotomy: Customized titanium plates (splintless technique) Three-dimensional (3D)-printed…
- Trial name
- NCT06933628
- Testing
- Patient-Specific Titanium Plates, 3D-Printed Intermediate Splint
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Malocclusion, Craniofacial Morphology
Research on Deep Learning-Based Intelligent Diagnosis and Treatment
This study aims to develop and evaluate deep learning-based artificial intelligence models for craniomaxillofacial multi-modal imaging analysis and clinical decision support.
- Conditions
- Malocclusion, Craniofacial Morphology, Dentofacial Deformities
- Trial name
- NCT07551622
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Dentofacial Deformities, Analgesia
Effects of Local Ketamine in Orthognathic Procedures
Orthognathic surgery is performed to correct congenital, developmental, or trauma-related skeletal deformities of the maxilla and mandible.
- Conditions
- Dentofacial Deformities, Analgesia, Vomiting, Postoperative, Nausea, Postoperative
- Trial name
- NCT07066306
- Testing
- Ketamine, Articaine Hydrochloride + Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Dentofacial Abnormalities, Dentofacial Deformities
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but…
- Conditions
- Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion
- Trial name
- OSP (NCT04117360)
- Testing
- Orthognathic surgery and Orthodontics
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Joint Disorders
Nasal Septum Autologous Chondrocytes Transplantation for Condylar Resorption After Orthognathic Surgery
This clinical study has as main objective to evaluate if the Nasal Septum Autologous Chondrocytes Transplantation for Condylar Resorption is safe and effective in the treatment of degenerative lesions of temporomandibular joint…
- Trial name
- NCT03137914
- Testing
- Autologous chondrocyte transplantation, orthognathic surgery
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Faculdade de Medicina de Petrópolis Faculdade Arthur Sá Earp Neto
Maxillary Deficiency
Comparative Results of Maxillary Deficiency Treatment by Fixed Tongue Appliance and Fixed Facemask in Growing Patients
A new fixed appliance will be used to transfer the tongue force during its physiological activity to advance the nasomaxillary complex; this method will be compared with the traditional method which uses a facemask with a fixed…
- Trial name
- NCT00916084
- Testing
- Fixed Tongue Appliance, Fixed Face Mask
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Dentofacial Deformities
Patient-Specific vs. Conventional Positioning in Sagittal Split Ramus Osteotomy
This study aims to evaluate the clinical efficacy and positioning accuracy of a custom-made proximal segment positioning appliance designed for use in sagittal split ramus osteotomy (SSRO).
- Trial name
- NCT07125963
- Testing
- Custom-made positioning appliance-assisted mandibular segment repositioning, Conventional Manual Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sümer Münevveroğlu
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dentofacial Deformities
Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis
Accuracy assessment through three-dimensional superposition of the post-operative volumetric CT and the digital therapeutic project files.
- Trial name
- MandiFirst (NCT06907745)
- Testing
- Bimaxillary Osteotomy
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Ankyloglossia, Speech Delay
Frenuloplasty for Speech and Myofunctional Outcomes
Children with ankyloglossia (tongue tie) can have abnormal tongue function, putting them at a disadvantage when it comes to speech and articulation.
- Conditions
- Ankyloglossia, Speech Delay, Dentofacial Abnormalities
- Trial name
- NCT06089629
- Testing
- Lingual frenuloplasty
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Oregon Clinic
Dentofacial Deformities
Correlation Between Dental Inclination and Bone Thickness in Patients With Class III Dentofacial Deformities
The correlation between tooth inclination and bone thickness and the comparison between thickness measurements and buccolingual inclination before and after dental decompensation will be evaluated through tridimensional images in…
- Trial name
- NCT02491619
- Testing
- orthodontic decompensation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Michelle Sendyk
Health-related Quality of Life, Dentofacial Deformities
Cross Cultural Adaptation and Validation of Orthognathic Quality of Life Questionnaire (OQLQ)
The aim of this study was to develop a Spanish version of the Orthognathic Quality of Life Questionnaire (OQLQ) that is conceptually equivalent to the original questionnaire, as well as acceptable, reliable, valid, and responsive…
- Trial name
- NCT04863170
- Testing
- orthognathic surgery
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malocclusion, Dentofacial Deformities
Augmented Reality for Orthognatic Surgery Patient Education
To evaluate whether the use of augmented reality (AR) for visualizing 3D models can be a valuable addition to patient education regarding orthognathic procedures compared to using only 2D visualization (on a computer screen).
- Conditions
- Malocclusion, Dentofacial Deformities, Patient Satisfaction, Informed Consent
- Trial name
- NARRATE (NCT06140043)
- Testing
- Patient consultation
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Class III Malocclusion, Skeletal Malocclusion
Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol
This study investigated two different methods of maxillary protraction in growing patients with skeletal Class III malocclusion characterized by maxillary deficiency.
- Conditions
- Class III Malocclusion, Skeletal Malocclusion, Maxillary Deficiency
- Trial name
- MiniFM (NCT07279662)
- Testing
- Skeletal Anchorage Supported Maxillary Protraction, Tooth-Borne Maxillary Protraction Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Murat Kaan Erdem
Class II Malocclusion, Dentofacial Deformities
Comparative Evaluation of Functional and Aesthetic Outcomes of Box and Mini-Wing Genioplasty Techniques
This retrospective cohort study aims to compare the effects of Mini Wing and Box genioplasty performed in conjunction with bimaxillary orthognathic surgery on upper airway area and soft tissue profile in adult patients with…
- Conditions
- Class II Malocclusion, Dentofacial Deformities, Retrognathia
- Trial name
- MWBOX (NCT07724743)
- Testing
- Mini Wing Genioplasty, Box Genioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital