Clinical trials: Dental Materials
Immediate Implant Placement, Gap Filling With e-PRF
Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material
Twenty-eight patients seeking prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant will be selected from the outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of…
- Conditions
- Immediate Implant Placement, Gap Filling With e-PRF, Gap Filling With Allograft
- Trial name
- NCT07445776
- Testing
- Allograft, e-PRF
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Decay
Effect of Aging on Micro-tensile Bond Strength and Color Stability of Self-adhesive Resin Composite
The objective of this study is to evaluate the micro-tensile bond strength of a newly self-adhesive resinous restorative material to dentin with and without application of universal bonding system (in-vitro) and to examine it's…
- Trial name
- NCT06463574
- Testing
- self-adhesive resin restoration
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Caries
Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal
The evolution of conservative dentistry that adopts the preservation of tooth structure and affected dentin that can remineralize and save the pulp from exposure, in addition to pain and fear that companies' traditional caries…
- Trial name
- NCT05733923
- Testing
- Traditional Escavation, Excavation with Sodium Hypochlorite Gel 2.5%., Excavation with Papacarie Duo
- Where
- Syria
- Volunteers
- 90 people
- Sponsor
- Damascus University
Dental Caries
DPBRN Longitudinal Study of Dental Restorations Placed on Previously Un-restored Surfaces
The purpose of this study is to assess the quality and expected lifespan of fillings recorded in the DPBRN "Reasons for placing the first restoration on permanent tooth surfaces" study, and the factors affecting how long the…
- Trial name
- NCT01201408
- Where
- 7 sites in United States, Denmark
- Volunteers
- 9,291 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Pulp Disease, Dental
Evaluation of Different Materials in Pulpotomy of Primary Molars
The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized…
- Trial name
- NCT05981352
- Testing
- mineral trioxide aggregate pulpotomy, Dehydrated amniotic membrane pulpotomy, Hyaluronic acid pulpotomy
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Pulp Disease, Dental
Sodiumhexametaphosphate as Pulp Capping Material for Primary Teeth
Sodiumhexametaphosphate will be tested as pulp capping material in comparison to MTA for primary teeth pulp therapy
- Trial name
- NCT06170775
- Testing
- Pulp therapy, Sodiumhexametaphosphate, MTA
- Volunteers
- 100 people
- Sponsor
- Minia University
Immediate Dental Implant, Socket Sealing
Socket Sealing Abutment With Immediate Implant
This study aimed to evaluate bone and soft tissue changes clinically and radio-graphically after using socket sealing abutment with or without bone graft material.
- Conditions
- Immediate Dental Implant, Socket Sealing, Molar Teeth
- Trial name
- NCT07748494
- Testing
- Immediate Molar Implant Placement with Grafting Material, Immediate Molar Implant Placement without Grafting Material
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Wear Comfort, Retention
3D Printed vs. Milled Occlusal Splints in Dentistry
This crossover study aims to evaluate the wear comfort, retention, and stability of 3D-printed and milled occlusal splints in healthy subjects.
- Conditions
- Wear Comfort, Retention, Stability
- Trial name
- Splints (NCT07236294)
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Prostheses, Endosseous Dental Implant Failure
Pink Esthetic Score Around Immediate Implants Using PDDM as Jumping Gap Filling Material.
Will there be a difference in Pink Esthetic score and soft tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix compared with xenograft?
- Trial name
- NCT05952765
- Testing
- Immediate implant
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apexogenesis, Pulp Exposure, Dental
Bioceramic Repair Materials in Apexogenesis of Immature Permanent Molars
The present study was conducted to compare the clinical, radiographic, and tomographic outcomes of apexogenesis using Bio-C Repair and Biofactor MTA in immature permanent first molars with vital asymptomatic pulp exposure.
- Conditions
- Apexogenesis, Pulp Exposure, Dental, MTA Vital Tooth Pulpotomy, Cone Beam Computed Tomography
- Trial name
- NCT07883239
- Testing
- Bioceramic Repair Pulpotomy (BIO-C® REPAIR), Mineral Trioxide Aggregate Pulpotomy (Biofactor MTA)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Pulpitis
A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies
Internal resorption in the most common cause of failure in FS pulpotomies in primary molars. This has been attributed to the release of free eugenol from the zinc and eugenol mixture of the base material over the pulp tissue.
- Trial name
- NCT05557812
- Testing
- non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies, eugenol based zinc oxide and Ferric Sulfate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Dental Restoration Failures
An In-vivo Survival Rate of Different Onlay Materials Placed Over Endodontically Treated Molar Teeth
This study aims to evaluate the survival rates of onlays placed over posterior endodontically treated teeth restored with zirconia, lithium disilicate and lithium disilicate reinforced with zirconia.
- Trial name
- NCT07753941
- Testing
- Monolithic zirconia partial coverage onlays, Lithium disilicate partial coverage onlays, zirconia-reinforced lithium disilicate partial coverage onlays
- Where
- Jordan
- Volunteers
- 39 people
- Sponsor
- Yousef Mahmoud Salem
Endodontically Treated Teeth, Postoperative Pain
Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life
Objective: The objective of this study will be to evaluate the effectiveness of different endodontic treatment techniques in postoperative symptoms, apical repair, longevity of rehabilitations, and oral health-related quality of…
- Conditions
- Endodontically Treated Teeth, Postoperative Pain, Edema, Photochemotherapy
- Trial name
- NCT03704857
- Testing
- Foraminal Enlargement / Irrigating solutions / Filling materials, Photobiomodulation, Passive ultrasonic irrigation
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Pulp Diseases, Dental Pulp Necrosis
Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy
The purpose of this study is to to compare root canal therapy success between two root canal filler materials: 1) gutta percha (GP), 2) gutta percha modified with nanodiamonds and amoxicillin (NDGX).
- Conditions
- Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
- Trial name
- NDGX (NCT03376984)
- Testing
- ND and AMOX modified Gutta Percha, Gutta Percha
- Where
- United States
- Sponsor
- University of California, Los Angeles
Nanotechnology, Dental Materials, Composites
Nano Composites and Light Cure Composites - A Comparative Assessment of Bond Failure Rates
This randomized clinical trial is aimed to evaluate the bond failure rates of the brackets bonded with nano-hybrid composites (Filtek Z250) to that of conventional composites (Transbond XT)
- Trial name
- NCT05644860
- Testing
- Nanohybrid Compisite Group (Filtek Z250), Conventional Composite Group (Transbond XT)
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Alveolar Bone Loss, Edentulism Nos
The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation
Pneumatization of the maxillary sinus may lead to insufficient bone volume for dental implant placement in the edentulous posterior maxilla.
- Trial name
- NCT06533397
- Testing
- Sinus floor elevation (SFE), preoperative cone beam computed tomography (CBCT), postoperative CBCT
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge
Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.
The purpose of the study is to compare soft tissue volume changes in terms of volume gain and stability around dental implants and PROMS in cases where a sub-epithelial connective tissue graft (SCTG) from the palate, Porcine…
- Conditions
- Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge, Edentulous Alveolar Ridge
- Trial name
- NCT04766255
- Testing
- Soft Tissue graft augmentation, Implant Placement
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Endodontic Treatment, Irreversible Pulpitis
A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment
The effect of Antibacterial Nanoparticles, Incorporated in root canal sealer material and in provisional restoration is going to be examined.
- Conditions
- Endodontic Treatment, Irreversible Pulpitis, Health Pulp, Infected Pulp
- Trial name
- IABN (NCT01167985)
- Testing
- IABN
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Implant
Effect of Bone Graft Material ON Peri-Implant Phenotype .
This prospective three-arm controlled interventional clinical study evaluates the effects of NanoBone alone and NanoBone combined with platelet-rich fibrin (PRF) on peri-implant hard and soft tissue phenotype after dental implant…
- Trial name
- NCT07835451
- Testing
- Dental implant placement, NanoBone, NanoBone sticky bone plus CGF/PRF membrane
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University