Clinical trials: Dental Diseases
Tooth Loss
Study Comparing Osseodensification With Standard Drilling
The purpose of this study is to examine how Osseodensification, a well-defined bone preparation procedure utilizing special densifying burs (a tool to prepare bone) compares to the standard drilling procedure utilizing regular…
- Trial name
- OD/SD (NCT04779203)
- Testing
- Osseodensification Densah Bur
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Jackson Implant Surgery
Vitamin D Deficiency, Osseointegration Failure of Dental Implant
Vitamin-D Insufficiency and Implants
Vitamin D is important for bone health, immune function, and inflammation, along with dental implant success. The study aimed to assess bone markers and cytokine levels in patients with and without vitamin D insufficiency to…
- Conditions
- Vitamin D Deficiency, Osseointegration Failure of Dental Implant, Peri-Implantitis
- Trial name
- NCT06452251
- Testing
- OPG, OC, RANKL, IL-10, IL-1β, Ca, TNF-α and Caspase-1 ELISA, Resonance Frequency Analysis, Periodontal clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vesile Elif Toy
Aerosol Disease, Caries,Dental
Quantitative Evaluation of Aerosols Produced in the Dental Office
Background: Maintaining biosafety in dental practice requires an efficient elimination of aerosols produced during dental treatment.
- Trial name
- NCT05988359
- Testing
- Caries treatment with a dental turbine, Caries treatment with Er:YAG laser
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Dental Caries
Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Despite the availability of free health dental service in Sri Lanka, the prevalence and severity of dental caries among 6year old school children stand at a very high level according to the results of national oral health survey…
- Trial name
- NCT02877888
- Testing
- fluoride varnish 22600ppm
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
Molar Incisor Hypomineralization
Clinical Efficacy of Calcium and Sodium Phosphosilicate (Novamin) in the Treatment of MIH (Molar Incisor Hypolimineralization) in Pediatric Patients
The aim of the following study is to evaluate the clinical efficacy of a toothpaste with calcium and sodium phosphosilicate in the treatment of demineralization of the dental enamel of molars and incisors in pediatric patients.
- Trial name
- NCT06396988
- Testing
- Novamin application, Parodontax application
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Pavia
Dental Caries
Microbial Testing for Caries Risk Assessment
Specific Aims 1) Assess CG (Cariogenic) Saliva-Check Mutans® saliva testing for identification of high caries risk patients
- Trial name
- NCT03389373
- Testing
- GC Strep Mutans Saliva Sampling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety, Dental
Virtual Reality Technology on Pain Perception and Anxiety Levels in Adolescents and Young Adults During Third Molar Germ Avulsion Surgery (VIDAMO)
For a long time, the fear of the dental surgeon has been the main reason why a percentage of the population avoids regular consultation.
- Trial name
- VIDAMO (NCT04609956)
- Testing
- Virtual reality, Standard
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chemotherapy Effect, Dental Caries
Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors.
- Conditions
- Chemotherapy Effect, Dental Caries, Malocclusion, Childhood Cancer
- Trial name
- NCT06517927
- Testing
- Clinical and radiographic dental examination
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Dental Caries, Secondary Dental Caries
A Comparative Study of Papacarie® and the Conventional Method for Dental Caries Treatment
The purpose study are to evaluate the efficacy of Papacarie® for caries removal in comparison to the conventional drilling method.
- Conditions
- Dental Caries, Secondary Dental Caries, Personal Satisfaction
- Trial name
- NCT01641861
- Testing
- Papacarie®, Conventional method
- Where
- Thailand
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Bone Resorption, Bacteria Caused Disease
0.2% Chx Gel vs Implant Bacterial Contamination
The objective of this human randomized, double blind, placebo-control (RDBPC) study is to evaluate the efficacy of a 0.2% chlorhexidine (CHX) gel on reducing bacterial load and peri-implant inflammation at implant-abutment…
- Trial name
- NCT03431766
- Testing
- 0.20% chlorhexidine gel
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Dental Caries
Clinical Performance of a Highly-filled Flowable Composite in Class III Restorations.
The aim of this study was to evaluate the 12-month clinical performance of a highly filled flowable composite resin in anterior teeth.
- Trial name
- NCT07051551
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
Reversible Pulpitis, Irreversible Pulpitis
Evaluation of Pulpal Biomarkers in Vital Pulp Therapy
This prospective clinical study aims to evaluate the association between the levels of selected pulpal biomarkers and the clinical success of vital pulp therapy in permanent teeth.
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Vital Pulp Therapy, Dental Pulp Diseases
- Trial name
- NCT07073573
- Testing
- Vital pulp therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- ertuğrul karataş
Patient Satisfaction, Dental Prosthesis
Correlation of Length of Index Finger to Vertical Dimensions of Occlusion for Edentulous Patients
This study is a randomized clinical trial comparing the conventional method of recording occlusal vertical dimension using Willis gauge from the base of the nose to the base of the chin with the other method using vernier caliper…
- Conditions
- Patient Satisfaction, Dental Prosthesis, Edentulous Jaw
- Trial name
- NCT05153213
- Testing
- Finger lengths, Conventional method
- Where
- Pakistan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Pain, Sensation Disorders
Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients
Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of…
- Trial name
- NCT06704113
- Testing
- meloxicam 7,5mg
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Tooth Loss
Ti-Mesh Frame Comparison for Alveolar Bone Augmentation
This research compares a chairside Titanium Mesh frame fabrication used during bone grafting procedures with the use of a computer-aided design/computer-assisted manufacture (CAD-CAM) Titanium Mesh frame.
- Trial name
- NCT06077513
- Testing
- CAD-CAM designed and preprinted Ti-Mesh frame, Conventional chairside fabrication of Ti-Mesh frame
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University
Dental Diseases
Evaluation of the Initial Color Match of Different Single-shade Composites
The aim of this study was to evaluate the initial colour match of anterior non-carious cervical lesions restored with different single-shade resin composites, namely Omnichroma (Tokuyama) and Charisma Topaz One (Kulzer).
- Trial name
- NCT06473727
- Testing
- Omnichoroma, Charisma Topaz One
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Caries,Dental
Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars
Stainless steel crowns have shown high success in restoring carious primary molars over a longer period of time than conventional restorations.
- Trial name
- NCT06597669
- Testing
- Placement of stainless steel crowns on primary molars
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Plaque, Denture Stomatitis
Efficacy of a Propolis-based Denture Cleanser
The purpose of this study is to assess if a propolis solution is able to remove plaque and kill microbes from complete dentures.
- Conditions
- Dental Plaque, Denture Stomatitis, Oral Candidiasis, Oral Hygiene
- Trial name
- NCT01237782
- Testing
- Denture soaking solution, Saline solution
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Raphael Freitas de Souza
This Study Aims to Evaluate the Effectiveness of the INJEX Device in Administering Local Anesthesia
Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia.
Local anesthesia is a common and essential procedure for the majority of dental treatments. The most frequently used method of administration is needle injection.
- Trial name
- NCT07426523
- Testing
- INJEX 30, Traditional syringe
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
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