Clinical trials: Dental Biofilm Accumulation
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
The purpose of the study is to assess the effect of enzyme containing lozenges on dental plaque accumulation in healthy adults.
- Trial name
- NCT05082103
- Testing
- Enzyme lozenge 1, Enzyme lozenge 2
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Gingivitis, Periodontitis
A Clinical and Imaging Study to Evaluate a Novel Dentifrice
There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health.
- Conditions
- Gingivitis, Periodontitis, Dental Plaque
- Trial name
- NCT02271815
- Testing
- Oral Hygiene
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, Irvine
Dental Biofilm Accumulation
Effect of Enzyme-containing Lozenge on Dental Biofilm Formation, Composition and Functionality
A double-blind, placebo-controlled randomized cross-over trial evaluating the effect of enzyme-containing lozenge on in vivo and in situ grown dental biofilm accumulation.
- Trial name
- NCT06142409
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Novozymes A/S
Dental Plaque, Gingivitis
Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.
The purpose of the study is to assess the effect of an enzyme containing lozenge on dental plaque accumulation in healthy adults.
- Conditions
- Dental Plaque, Gingivitis, Microbial Colonization
- Trial name
- NCT05070507
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Mouthwashes, Chlorhexidine
Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining
Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with…
- Conditions
- Mouthwashes, Chlorhexidine, Dental Plaque, Gingival and Periodontal Disease
- Trial name
- NCT07351370
- Testing
- chlorhexidine/ cetylpyridinium chloride/ hydrogen peroxide mouthwash, Chlorhexidine/ cetylpyridinium chloride
- Where
- Greece
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Dental School
Dental Biofilm Accumulation
RCT: Enzyme Blend Toothpaste on Dental Biofilm Plaque Accumulation
The aim of the study is to investigate whether brushing twice a day with a toothpaste (Biofresh Clean) containing a blend of alpha-amylase and gluco-amylase improves oral health outcomes over a 14-day period.
- Trial name
- NCT07079683
- Testing
- Toothpaste Product
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation
Double-blind, placebo-controlled, cross-over study investigating dental biofilm accumulation after 4-days in 28 subjects randomised to receive: Sequence 1: 5 active enzyme-containing lozenges per day for 4-days followed by a…
- Trial name
- NCT05579938
- Testing
- Enzyme-containing lozenge
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Caries
Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances
Caries is a biofilm-mediated global public health problem causing health, social and economic consequences for individuals, communities and countries.
- Trial name
- NCT05033015
- Testing
- Mouth rinse
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Malmö University