Clinical trials: Delayed Bleeding
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
MicroRNA Diagnostics in Subarachnoid Hemorrhage 2
The purpose of this study is to validate results from a related trial (NCT01791257) and to compare the profile of microRNA in blood from patients suffering subarachnoid hemorrhage with and without systemic complications.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Acute Lung Injury, Cardiac Dysfunction
- Trial name
- NCT02320539
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome
Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage
Intracranial hemorrhage is a condition characterized by high mortality rates and suboptimal functional outcomes. It precipitates both direct brain injury and subsequent secondary injuries, including delayed cerebral ischemia…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome, Mass Spectrometry, Heart Failure
- Trial name
- NCT06906432
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Delayed Cerebral Ischemia After Subarachnoid Hemorrhage, Ischemic Stroke of Large or Medium Vessels
Thrombo-inflammation in Acute Neurovascular Diseases: Definition of New Therapeutic Targets (TARGETS)
The objective of this observational study is to compare the relative concentrations of various thrombo-inflammatory markers at different follow-up time points in: patients with or without delayed cerebral ischemia after…
- Trial name
- NCT07354321
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- François Delvoye
Hemorrhage, Coagulation Delay
Evaluation of Novel Point of Care Coagulation System in Pregnant Women
In this study the investigators will evaluate a new point of care Quantra Hemostasis Analyzer system to assess coagulation rapidly with ease.
- Trial name
- CCPW (NCT04301193)
- Testing
- Quantra Analyzer
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Craniocerebral Trauma, Stroke
Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes
This prospective, randomized study aims to comprehensively evaluate the impact of cranioplasty timing on postoperative complications and long-term functional outcomes following decompressive hemicraniectomy (DHC).
- Conditions
- Craniocerebral Trauma, Stroke, Intracranial Hemorrhages
- Trial name
- TIMELY (NCT06632587)
- Testing
- Early cranioplasty, Standard-of-care cranioplasty
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Contraceptive Usage
Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents
The specific aim of this study is to evaluate whether insertion of a long-acting contraceptive implant in postpartum adolescents prior to hospital discharge increases use of this highly effective contraception during the first…
- Trial name
- Implanon (NCT03585504)
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit
The goal of this observational study is to investigate DNA methylation changes in adults with bleeding from brain aneurysm, which is called aneurysmal subarachnoid hemorrhage (aSAH), and their association with delayed ischemic…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm After Subarachnoid Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT06881329
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Acute Kidney Injury
Cystatin c: a Biomarker of AKI in Aneurysmal Subarachnoid Haemorrhage Patients
The goal of this observational study is to assess cystatin c as a predictive biomarker of early acute kidney injury in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT06635408
- Testing
- cystatin c
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage
Management of Large Retained Products of Conception (> 4 cm): Need for an Standardized Procedure.
Collection of relevant data form patients who were treated in the Ghent University Hospital in the context of a placental remnant lager than 4 cm, performing statistical analyzes on the collected data, reviewing the literature on…
- Conditions
- Placenta, Retained, Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage, Placenta; Retention, Fragments, Complicating Puerperium (Delayed Hemorrhage), Pregnancy Related
- Trial name
- NCT04720885
- Testing
- kind of surgery
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Intraventricular Hemorrhage
VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants
The purpose of this study is to determine whether providing ventilatory assistance prior to umbilical cord clamping influences the occurrence of intraventricular hemorrhage (IVH) in extremely preterm (EPT) infants, compared to…
- Trial name
- NCT02742454
- Testing
- Standard 30-60 Seconds Cord Clamping, VentFirst 120 Seconds Cord Clamping
- Where
- 12 sites in United States, Canada
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Procedural Bleeding, Delayed Bleeding
A Comparison of Eleview Versus Hetastarch as Injectate for EMR
EMR is a technique used for the removal of flat or sessile neoplasms confined to the superficial layers of the GI tract using a snare.
- Conditions
- Procedural Bleeding, Delayed Bleeding, Post-Polypectomy Syndrome, Post Procedural Complication
- Trial name
- NCT03350217
- Testing
- Eleview, Hetastarch
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Delivery Delayed, Mode of Delivery
Early Versus Delayed Oxytocin Infusion Following Amniotomy in Nulliparous Women
In UKM Medical Centre (UKMMC), delayed oxytocin augmentation at two hours following amniotomy is the routine obstetric practice in spontaneous or induced labour with intact membranes.
- Conditions
- Delivery Delayed, Mode of Delivery, Post Partum Hemorrhage, Uterine Hyperstimulation
- Trial name
- NCT04200599
- Testing
- duration of initiation of oxytocin
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postpartum Hemorrhage
Postpartum Oxytocin Administration in the Era of Delayed Cord Clamping
Increased blood loss after vaginal or cesarean delivery is one of the top causes of maternal complications. Oxytocin is a common medication given to mothers by IV or an injection to limit the amount of blood loss after delivery.
- Trial name
- PROCEEDING (NCT04632264)
- Testing
- Initiation of standard postpartum oxytocin immediately following fetal shoulder delivery, Initiation of standard postpartum oxytocin immediately following placenta delivery
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Columbia University
Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage
Timing of Umbilical Cord Occlusion in Premature Babies( <33 w). Delayed vs Early.
Early cord clamping after delivery has been common practice for many decades as part of the active management of the third stage of labour.
- Conditions
- Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage, Intraventricular Haemorrhage
- Trial name
- CODE-P (NCT02187874)
- Testing
- delayed umbilical cord occlusion, early umbilical cord occlusion, Oxytocin
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Traumatic Brain Injury, Intracerebral Hemorrhage
Near Infra-red Spectroscopy for Detection of Intracranial Haematoma
Fall with head injury is becoming an epidemic challenge especially with the ageing population. Contributing factors for mortality and poor functional outcome included development of cerebral contusion and delayed traumatic…
- Trial name
- NCT03653728
- Testing
- Near infrared spectroscopy
- Where
- Hong Kong
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Delayed Cord Clamping, Hemoglobin
The Effect of Time Window for Umbilical Cord Clamping During Cesareans on Offspring Hemoglobin and Maternal Blood Loss
This is a randomized controlled trial, aiming to evaluate the effects of time window for umbilical cord clamping during cesarean section on the health outcomes of offspring hemoglobin，maternal blood loss，and children's growth and…
- Conditions
- Delayed Cord Clamping, Hemoglobin, Blood Loss
- Trial name
- NCT05492214
- Testing
- Delayed cord clamping (30s), Delayed cord clamping (60s), Delayed cord clamping (90s)
- Where
- 2 sites in China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Peking University
Patient Comfort, Postpartum Hemorrhage
The Effect of Skin-to-skin Contact on Placental Separation Time, Type, Postpartum Hemorrhage and Comfort
It is aimed to determine the late cord clamping with early skin-to-skin contact in primiparous pregnant women who delivered vaginally, according to placental separation time, separation method, amount of postpartum bleeding and…
- Conditions
- Patient Comfort, Postpartum Hemorrhage, Midwifery, Placenta
- Trial name
- NCT06011096
- Testing
- skin-to-skin contact and delayed cord clamping, avoiding skin-to-skin contact and early cord clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bahar GÖBEL